Lead the strategy and governance of the Description data domain for structured regulatory submissions, aligning product, material, and CMC data across R&D, Supply Chain, Regulatory, and Quality. Define standards, business requirements, and data products to support SPQS, IDMP, and digital regulatory capabilities, working closely with technology teams on SAP PLM and future system-of-record solutions.
A Safety Scientist in GSK's Safety Evaluation and Risk Management (SERM) team leads signal detection, safety evaluations, and risk management for pharmaceutical products in clinical development and post-marketing. The role involves authoring safety reports, contributing to Risk Management Plans, and collaborating across global teams to ensure patient safety. The position supports governance activities and requires strong scientific, medical, and pharmacovigilance expertise.
The role involves leading the development and execution of precision medicine strategies within global clinical programs, focusing on biomarker and diagnostic initiatives for patient selection and regulatory support. It requires close collaboration with cross-functional teams and external partners, ensuring compliance with medical device regulations and high-quality scientific delivery. The position is embedded in the Neuroscience disease area, emphasizing strategic input into clinical trial design and regulatory submissions.
The Precision Medicine Director leads the development and execution of biomarker and diagnostic strategies within global clinical programs, focusing on patient selection and regulatory-aligned trial design. This role acts as a scientific expert, guiding cross-functional teams in neuroscience-focused initiatives and ensuring compliance with medical device regulations. The position emphasizes strategic leadership in precision medicine, with strong collaboration across clinical development, diagnostics, and external research partners.
This role involves designing and executing biological screening cascades to validate computational predictions in drug discovery. The scientist will lead biophysical, biochemical, and cellular assay development, collaborate with CROs, and bridge AI-driven insights with experimental validation across oncology and immunology programs. Close collaboration with medicinal chemistry, structural biology, and machine learning teams ensures data informs rational drug design.
This role involves leading and implementing regional regulatory strategies for oncology products in the Rest of World (ROW) region, ensuring alignment with global objectives and commercial goals. The individual will represent the region on the Global Regulatory Strategic Team, manage submissions and approvals, and shape interactions with health authorities. A key focus is ensuring compliance while influencing the regulatory environment to accelerate patient access to medicines.
Leads regional regulatory strategy for oncology products across the Rest of World (ROW), ensuring alignment with global objectives and timely submissions to health authorities. Works closely with cross-functional teams and external agencies to shape regulatory pathways, influence policy, and secure commercially viable labeling. Focuses on compliance, risk mitigation, and strategic engagement in a dynamic regulatory environment.
This role involves developing machine learning models grounded in quantum chemistry to accelerate small-molecule drug discovery. The scientist will create synthetic datasets using quantum mechanical methods, build scalable and reproducible ML pipelines, and collaborate with computational and experimental teams to model molecular energetics and protein–ligand interactions. Work contributes directly to drug design tools at Roche, with opportunities for scientific publication and open-source contributions.
Develop machine learning models grounded in quantum chemistry to accelerate small-molecule drug discovery. Create synthetic datasets using quantum mechanics and build scalable, deployable pipelines integrated into molecular design tools. Collaborate with computational and experimental scientists to advance drug discovery through publications and open-source contributions.
Lead clinical pharmacology strategy for small molecule programs in oncology and non-oncology areas, designing and executing studies from Phase 1 through late development. Utilize AI-driven models for PK/PD prediction, dose optimization, and regulatory submissions, while managing CROs and translating preclinical data into human dosing strategies.
Medical Devices Consultant - Senior Mechanical Engineer - CambridgeDue to the growth of a leading Medical Devices organisation, we are currently seeking a Senior Mechanical Engineer, Project Manager, Medical Devices Inventor, or Mechanical Design Consultant for a newly approved role....
Leads end-to-end translational strategies for respiratory disease programmes, integrating human biology, multi-omics data, and biomarker development to de-risk clinical decisions. Designs and implements target validation, patient stratification, and precision medicine approaches while collaborating across discovery, clinical, and data science teams. Drives biomarker strategy into clinical protocols and regulatory submissions, using AI/ML and innovative assays to generate actionable insights.
This role involves designing and delivering biomarker strategies and assays to support clinical development in respiratory and immunologic diseases. The scientist will lead biomarker studies using human biospecimens, interpret complex datasets, and provide evidence-based recommendations to guide trial design and patient selection. Working at the interface of lab science and clinical development, the role emphasizes assay development, cross-functional collaboration, and the application of advanced translational technologies.
Lead the end-to-end operational execution of Clinical Trial Applications (CTAs) outside the US, ensuring regulatory compliance and timely submissions across global markets. Serve as the subject matter expert on UK clinical trial regulations, including MHRA requirements and evolving legislation, while leveraging digital tools and AI-enabled technologies to enhance regulatory operations. Collaborate with cross-functional teams and CROs to maintain inspection-ready documentation and drive continuous improvement in regulatory processes.
Lead the operational execution of Clinical Trial Applications (CTAs) globally outside the US, with a focus on compliance, submission excellence, and cross-functional coordination. Serve as the subject matter expert for the UK clinical trial regulatory landscape, including MHRA requirements and evolving legislation. Leverage digital platforms and AI-enabled tools to enhance regulatory operations and submission efficiency across international markets.
