Jobs in Cambridge

Senior Global Clinical Operations Director

This role leads the operational strategy and end-to-end delivery of global clinical programs in oncology, spanning early and late-phase development. The director will drive trial design, cross-functional collaboration, and regulatory readiness while managing complex multinational studies, CRO partnerships, and high-performing teams. Emphasis is placed on innovation, efficiency, and patient impact through advanced trial methodologies and strategic leadership.

AstraZeneca Cambridge, United Kingdom

Hybrid Permanent

Senior Scientist or Associate Principal Scientist Metabolist Team

This role involves conducting advanced in vitro and ex vivo research to identify and validate therapeutic targets for obesity. The successful candidate will work in a dynamic, collaborative environment, designing and implementing experiments, analyzing data, and contributing to drug discovery projects across multiple sites.

AstraZeneca Cambridge, United Kingdom

On-site Permanent

Head of Precision Diagnostics External Engagement

This senior role involves leading business development and transactions in biomarker and diagnostics for GSK's Oncology R&D. Responsibilities include negotiating deals, aligning with R&D strategy, and collaborating with internal and external stakeholders to drive successful collaborations.

GSK United States £242,250 – £403,750 pa

On-site Permanent

Head of Precision Diagnostics External Engagement

This senior role involves leading business development and transactions in biomarker and diagnostics for GSK's Oncology R&D. Responsibilities include negotiating deals, aligning with R&D strategy, and collaborating with internal and external stakeholders to drive strategic alliances and complex collaborations.

GSK £242,250 pa

On-site Permanent

Director, Medical Insights

The Director, Medical Insights role involves shaping and implementing processes to generate high-quality medical insights. Key responsibilities include developing strategies, prioritizing use cases, and applying advanced analytics and AI to inform medical decision-making. The role also focuses on embedding insights into core medical processes and collaborating with various stakeholders to ensure effective use of insights.

Pfizer

On-site Permanent

Director, Medical Insights

The Director, Medical Insights role involves shaping and implementing Medical Insights processes, collaborating with various stakeholders to generate actionable insights, and embedding these insights into medical decision-making. The role focuses on leveraging advanced analytics and AI to translate complex medical data into strategic decisions, ensuring consistency and value across Pfizer’s medical portfolio.

Pfizer

On-site Permanent

Senior Director, Portfolio Integration Lead - Hematology

This role leads cross-programme scientific strategy and integration across GSK’s oncology portfolio, with a focus on hematology. The Senior Director ensures alignment in clinical development, biomarker strategy, and trial innovation across multiple assets, acting as a scientific partner to Clinical Development Leads and shaping portfolio-level decision-making. The position emphasizes data-driven innovation, external engagement, and strategic coherence in a matrixed R&D environment.

GSK US$242,250 – US$403,750 pa

Hybrid Permanent

Senior Director, Portfolio Integration Lead - Hematology

This role involves providing scientific leadership across GSK's hematology oncology portfolio, ensuring strategic alignment and integration across multiple clinical development programs. The Senior Director will drive innovation in trial design, biomarker strategies, and data-driven decision-making while serving as a key advisor to clinical teams and external stakeholders. The position requires deep expertise in oncology drug development and the ability to shape cross-asset portfolio strategy.

GSK US$242,250 – US$403,750 pa

Hybrid Permanent

Senior Director, Portfolio Integration Lead - Hematology

Leads cross-programme scientific strategy and integration for GSK's hematology oncology portfolio, ensuring alignment across clinical development, biomarker strategies, and innovation initiatives. Acts as a senior scientific partner to clinical teams, drives portfolio-level decision-making, and shapes engagement with external experts and regulatory bodies. Focuses on advancing novel therapies through data-driven insights, clinical trial innovation, and precision medicine approaches.

GSK US$242,250 – US$403,750 pa

Hybrid Permanent

Senior Manager - CMC Regulatory Affairs Biopharm Development Projects

This role involves leading CMC regulatory activities for GSK's investigational, late development, and early commercial products. Responsibilities include driving CMC strategy, preparing regulatory documents, managing project activities, mentoring staff, and engaging with external agencies to ensure compliance and expedite submissions.

GSK Canterbury, United Kingdom

On-site Permanent

Senior Director Clinical Operations Asset Lead - Hepatology, renal and cardiovascular disease

This role leads clinical operations for high-impact, complex global trials in hepatology, renal, and cardiovascular disease, with a focus on late-phase outcomes studies and rare diseases. The position shapes operational strategy, drives innovation in trial design, and ensures delivery across a diverse asset portfolio. It involves leading vendor partnerships, managing regulatory and quality compliance, and developing clinical teams within a patient-ambitious, data-driven environment.

GSK Stevenage, United Kingdom US$242,550 – US$404,250 pa

Hybrid Permanent

Executive Medical Director, Clinical Development Lead - Oncology - Lung & Head/Neck Cancers

This role leads clinical strategy and scientific vision for oncology assets focused on lung and head/neck cancers, shaping end-to-end development from discovery to approval. The Executive Medical Director acts as the principal clinical authority, integrating advanced analytics and AI-driven insights to accelerate decision-making, while representing Clinical Development in governance, regulatory interactions, and external collaborations. They will mentor talent and drive innovation across a dynamic, matrixed R&D environment.

GSK Stevenage, United Kingdom US$242,250 – US$403,750 pa

Hybrid Permanent

Senior Manager - CMC Regulatory Affairs Biopharm Development Projects

This role involves leading CMC regulatory activities for GSK's investigational, late development, and early commercial products. Responsibilities include driving CMC strategy, preparing regulatory documents, managing project activities, and mentoring staff. The position requires a strong understanding of regulatory requirements and the ability to communicate complex issues across departments and with external agencies.

GSK

On-site Permanent

Senior Director Clinical Operations Asset Lead - Hepatology, renal and cardiovascular disease

This role leads clinical operations for complex, multi-indication assets in hepatology, renal, and cardiovascular disease, with strategic oversight of global Phase III trials, rare disease programmes, and co-development partnerships. The position involves shaping operational strategy, managing high-level vendor relationships, and driving innovation in trial design including decentralised and hybrid models. It requires leadership in risk management, data-driven decision-making, and team development within a global regulatory and compliance framework.

GSK United Kingdom US$242,550 – US$404,250 pa

On-site Permanent

Senior Director Clinical Operations Asset Lead - Hepatology, renal and cardiovascular disease

This role leads clinical operations for high-complexity assets in hepatology, renal, and cardiovascular disease, with a focus on global Phase III outcomes trials, rare disease programmes, and co-development partnerships. The position drives end-to-end operational strategy, including country and site selection, patient recruitment, risk management, and vendor oversight, while ensuring alignment with clinical development and evidence generation plans. It also involves direct leadership of clinical teams, fostering innovation in trial design, and maintaining inspection readiness across the portfolio.

GSK US$242,550 – US$404,250 pa

On-site Permanent