Jobs in London

Compound Coordinator (Chemistry Data Generation, Drug Discovery), London

This role involves coordinating compound management and supply across external CROs to support drug discovery data generation efforts. The coordinator will streamline processes, ensure timely chemical procurement, and support internal registration systems. It sits at the intersection of chemistry operations and AI-driven drug design, requiring strong organisational skills and collaboration with both scientific and technical teams.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Head of Medicinal Chemistry, Drug Design, London

Lead and strategically guide a team of 25 medicinal chemists in redefining drug discovery through deep integration with AI and machine learning. Shape the scientific direction of projects from hit identification to candidate nomination, while fostering collaboration across computational design, biology, and pre-clinical development teams. Drive innovation by challenging traditional paradigms and embedding an AI-first culture across the chemistry function.

Isomorphic Labs London, United Kingdom

On-site Permanent

Senior Manager, PV Operations

This role leads global pharmacovigilance operations for a gene therapy company, overseeing safety case management, regulatory reporting, and compliance across clinical and post-marketing portfolios. The individual ensures robust, scalable processes and systems, including vendor oversight, safety database administration, and audit readiness. They play a key technical and operational role in SOP development, inspection preparedness, and cross-functional collaboration to support signal detection and risk management.

Orchard Therapeutics London, United Kingdom

Hybrid Permanent

Director, Pharmacovigilance

Leads global pharmacovigilance and safety strategy for gene therapy products, overseeing signal management, risk assessment, and benefit-risk profiling across investigational and marketed phases. Provides medical oversight for clinical trials, including safety data review, SAE evaluation, and regulatory submissions. Collaborates cross-functionally to ensure compliance with global safety regulations and supports health authority interactions on product safety matters.

Orchard Therapeutics London, United Kingdom

Hybrid Permanent

Global Labelling Associate Director, Content (Established Products)

Leads the development and maintenance of global labelling strategies and core documents for established pharmaceutical products, ensuring scientific accuracy and regulatory compliance. Facilitates cross-functional alignment and contributes to responses to health authority queries. Works within a hybrid or remote model depending on location, supporting consistent labelling across global markets.

Novartis London, United Kingdom

Hybrid Permanent

Global Labelling Associate Director, Content (Oncology)

This role involves developing and maintaining global labelling strategies and core documentation for oncology products across their lifecycle. The individual will lead cross-functional alignment on labelling content, interpret clinical data, and ensure compliance with global regulatory standards. They will also support health authority interactions and contribute to strategic planning and risk mitigation.

Novartis London, United Kingdom

Hybrid Permanent

Senior Medical Director, Oncology Clinical Development - Lung

This role involves leading oncology clinical development for lung cancer programmes, providing medical oversight across study design, execution, and data interpretation. The Senior Medical Director ensures patient safety, guides cross-functional teams, and represents the programme in regulatory and scientific forums. Based on-site with a future relocation to Cambridge, UK, the position emphasizes strategic clinical leadership within a global biopharma environment.

GSK

On-site Permanent

Senior Medical Director, Oncology Clinical Development - Lung

This role involves leading oncology clinical development for lung cancer programmes, providing medical oversight across study design, execution, and data interpretation. The Senior Medical Director ensures patient safety, contributes to regulatory engagements, and mentors medical teams within a cross-functional environment. The position integrates physician expertise into clinical strategy and external scientific forums, focusing on advancing care in high unmet need cancers.

GSK

On-site Permanent

Forward Deployed AI Engineer

This role involves deploying and integrating generative AI models into pharmaceutical and biotech customers' scientific workflows. The engineer will lead end-to-end technical deployments, build production-grade API integrations and data pipelines, and act as a technical liaison between customers and internal research teams. A strong background in ML infrastructure, cloud platforms, and customer-facing delivery in life sciences is essential.

Latent Labs London, United Kingdom, United Kingdom

Hybrid Permanent

Manager, Computational Biology (Early Oncology)

Lead a team of computational biologists to integrate multi-omics data for oncology target discovery and validation, while actively contributing to data analysis and cross-functional decision-making. Develop biomarker strategies and patient stratification approaches to guide therapeutic development. Collaborate closely with biologists, chemists, and clinical teams to advance drug programs using high-dimensional datasets and scalable computational methods.

Recursion United Kingdom US$151,800 – US$230,000 pa

Hybrid Permanent

Director, Clinical Science

Lead clinical strategy and execution for early-phase trials, authoring key clinical documents and overseeing medical monitoring. Serve as primary liaison with investigative sites and internal teams, ensuring data integrity across multiple oncology and hematology studies. Operate in a fast-paced, AI-driven drug discovery environment with cross-functional collaboration.

Recursion United Kingdom US$212,900 – US$287,980 pa

Remote Permanent

Global Medical Affairs Director, Immunology, Rap-cel (CAR-T)

Leads global medical strategy for a novel CAR-T therapy in autoimmune diseases, driving evidence generation and scientific engagement with key opinion leaders, patient groups, and research institutions. Oversees real-world evidence, registries, and investigator-initiated studies while ensuring compliance and medical governance. Collaborates cross-functionally to shape clinical development, regulatory, and launch strategies in a rapidly evolving immunology landscape.

Novartis London, United Kingdom £93,870 – £174,330 pa

Hybrid Permanent

Global Program Safety Lead - CRM

This role involves leading the end-to-end safety strategy for priority pharmaceutical programs in the Cardio Renal Metabolism (CRM) therapeutic area, from development through lifecycle management. The individual will serve as the scientific safety leader, driving safety governance, benefit-risk assessments, and regulatory interactions, while mentoring teams and embedding safety insights across global functions. It requires deep expertise in pharmacovigilance, cross-functional leadership, and clear communication of complex safety data.

Novartis London, United Kingdom £83,510 – £155,090 pa

Clinical Development Director - Renal

The Clinical Development Director leads and supports clinical development activities within a global program, focusing on strategy, trial execution, data analysis, and regulatory documentation. This role involves close collaboration with cross-functional teams, ensuring scientific rigor and data quality across phases I–IV trials, particularly in late-phase development. The position requires strong scientific expertise, leadership in clinical operations, and active participation in safety and regulatory initiatives.

Novartis London, United Kingdom

Hybrid Permanent

Director, Clinical Pharmacology

Lead clinical pharmacology and pharmacometrics strategy for rare disease and oncology programs, designing studies and guiding regulatory submissions. Oversee modeling and simulation to inform dose selection and accelerate drug development. Collaborate across translational, clinical, and preclinical teams in a tech-driven biopharma environment.

Recursion United Kingdom US$212,900 – US$297,000 pa

Hybrid Permanent