Jobs in Cambridge

Research Leader / Senior Scientist (Medicinal Drug Design), Cambridge, MA

Lead or contribute to drug discovery projects at the intersection of medicinal chemistry and AI, guiding programs from initiation to candidate selection. Collaborate closely with machine learning scientists to refine AI-driven drug design models and drive innovation in synthetic organic chemistry. Play a key role in shaping next-generation therapeutic development through strategic input, CRO management, and intellectual property generation.

Isomorphic Labs Cambridge, United Kingdom

Research Leader / Senior Scientist (Computational Drug Design), Cambridge, MA

Lead or contribute to drug discovery programs using AI-first approaches, integrating computational chemistry with machine learning to design novel therapeutics. Guide project strategy from hit identification through candidate selection, while collaborating closely with ML scientists and cross-functional teams. Help shape and refine AI models for drug design, with opportunities to lead teams and drive innovation in a dynamic, interdisciplinary environment.

Isomorphic Labs Cambridge, United Kingdom

Clinical Development Medical Director- Hepatology

Lead clinical development strategy and execution for hepatology assets within GSK’s R&D pipeline, driving early-phase programs from target identification through proof of concept. Provide medical oversight, design translational studies, and guide cross-functional teams to deliver innovative therapies for liver disease with a focus on scientific rigor and patient impact.

GSK

Hybrid Permanent

Medical Director, Oncology Clinical Development - Lung & Head/Neck Cancers

The Medical Director, Oncology Clinical Development is responsible for providing medical expertise in the design, conduct, and interpretation of clinical studies for lung and head/neck cancers. Key responsibilities include medical monitoring, safety oversight, protocol development, and collaboration with cross-functional teams and external experts.

GSK United States £222,750 – £371,250 pa

Director, Quantitative Systems Pharmacology

This role involves leading the development and application of quantitative systems pharmacology (QSP) models to advance drug discovery and development. Responsibilities include building mechanistic models, collaborating with cross-functional teams, and driving model-informed drug development strategies.

GSK

Associate Director, Pipeline Project Management for BD

The Associate Director, Pipeline Project Management for Business Development at GSK manages R&D projects from early diligence through integration and transition to business as usual. Key responsibilities include cross-functional planning, risk management, and ensuring smooth knowledge transfer and execution of BD transactions.

GSK Canterbury, United Kingdom

Associate Director, Global Program Management (Oncology)

The Associate Director, Global Program Management (Oncology) at GSK will lead the development and execution of integrated project plans for R&D pipeline projects. Key responsibilities include facilitating asset strategy, managing project risks, and ensuring high-quality data and reporting. The role involves working closely with cross-functional teams to optimize project delivery and drive strategic decisions.

GSK United States £139,425 – £232,375 pa

Associate Director, Global Program Management (Oncology)

The Associate Director, Global Program Management (Oncology) at GSK will lead the development and execution of integrated project plans for R&D pipeline projects. Key responsibilities include facilitating asset strategy, managing project risks, and ensuring high-quality data and reporting. The role involves working closely with cross-functional teams to optimize project delivery and drive strategic decisions.

GSK

Director, Clinical Operations Asset Lead

Leads clinical operations for a key asset across its full lifecycle, setting the operational strategy and ensuring high-quality, on-time delivery of clinical studies. Works cross-functionally to align study execution with scientific and regulatory goals, driving innovation and efficiency while managing risk and stakeholder engagement. Focuses on patient-centric approaches and inspection readiness within a global, matrixed environment.

GSK Stevenage, United Kingdom US$189,750 – US$316,250 pa

Director, Clinical Operations Asset Lead

Leads clinical operations strategy and execution across the full lifecycle of a key asset, ensuring operational feasibility, regulatory compliance, and high-quality delivery of clinical studies. Works cross-functionally to align study design with scientific vision, manages vendor and resourcing strategies, and drives innovation in patient-centric trial execution. Serves as primary point of accountability for global clinical operations at the asset level.

GSK Canterbury, United Kingdom

Hybrid Permanent

Director, Clinical Science – Oncology Clinical Development

Lead scientific input into oncology clinical trial design, data interpretation, and regulatory documentation within a global pharmaceutical environment. Contribute to study-level execution and strategic insights while collaborating across multidisciplinary teams. Focus on advancing cancer therapies with high unmet need through rigorous clinical science and cross-functional partnership.

GSK Stevenage, United Kingdom PLN 472,500 – PLN 787,500 pa

Hybrid Permanent

Product Director, DevOps & CMO Performance

The Product Director, DevOps & CMO Performance role at GSK involves leading the development and delivery of Mission Control, a flagship AI-driven platform for optimizing clinical trial operations. Responsibilities include setting the technical roadmap, managing AI applications, ensuring compliance, and leading a multi-vendor delivery ecosystem.

GSK Stevenage, United Kingdom

AI Transformation & Enablement Director

The AI Transformation and Enablement Director role at GSK involves driving the adoption of AI across clinical operations, defining the strategy and roadmap, and ensuring measurable improvements in clinical trial outcomes. The role requires deep expertise in AI, pharmaceutical clinical development, and strategic planning.

GSK Stevenage, United Kingdom

AI Transformation & Enablement Director

This role involves driving the adoption of AI across GSK's clinical operations, shaping the strategy and roadmap for AI transformation, and defining how AI will change the function's operating model. The Director will lead a team, manage stakeholder relationships, and ensure the deployment of AI tools that improve clinical trial outcomes and patient care.

GSK United Kingdom

Director, Clinical Science – Oncology Clinical Development

Lead scientific strategy for oncology clinical studies, contributing to protocol design, data interpretation, and regulatory deliverables within a global pharmaceutical environment. Collaborate across functions to ensure scientific rigor and alignment with clinical development goals, while engaging with external experts and supporting regulatory submissions. The role emphasizes innovation, data-driven decision-making, and continuous improvement in clinical development processes.

GSK £189,750 – £316,250 pa

Hybrid Permanent