Biotechnology Jobs

• London
• Hybrid · 3 days in office
• Lead

Lead formulation strategy for small molecules across drug discovery and preclinical development, designing technologies such as solid dispersions and co-crystals to improve solubility, stability and manufacturability. Work within an interdisciplinary team alongside AI/ML drug design platform groups, managing external CRO resources and authoring regulatory submissions.

ASAP

• London
• Hybrid · 3 days in office
• Lead

Drive DMPK strategy across drug discovery projects, designing screening cascades and mechanistic experiments while integrating AI/ML and PBPK modelling to predict human dosing, efficacy and safety windows. Work within an interdisciplinary team of drug design and machine learning specialists, authoring regulatory documents and optimising molecule design with chemistry leads.

R · Python · KNIME

• Oxford
• On-site
• £40,000 pa
• Entry level

Develops generative protein design models that capture enzyme dynamics and function, designing conformationally dynamic catalysts. Runs computational and statistical analyses, publishes findings, and collaborates with in vivo evolution teams across the institute. Also mentors PhD students and research assistants and pursues translational and IP opportunities.

• Oxford
• On-site
• £40,000 pa
• Entry level
• Permanent

Postdoctoral researchers design and execute experiments within the Generative Biology Institute, working at the interface of biology, technology and engineering to make biology engineerable. The role involves contributing to high-impact publications and mentoring junior researchers and students, supported by technology hubs for sequencing, imaging, automation and substantial compute resources. Positions span multiple research groups at a new Oxford Science Park facility.

Mass Spectrometry · Flow Cytometry · Sequencing +5

• Oxford
• On-site
• £39,424 – £47,779 pa
• Entry level
• Contract

Develop novel statistical and machine learning methods for large-scale genomic, phenotypic and health data, covering areas such as genomic language models, multimodal and federated learning, and multi-ancestry methods. Implement reproducible research software, apply it to biobank-scale datasets, evaluate statistical and predictive performance, publish findings and guide junior researchers.

• Oxford
• On-site
• £39,424 – £43,984 pa
• Entry level
• Contract

Carries out laboratory research on synthetic genome DNA assembly, generating constructs and testing new approaches using recombinant DNA methylases. Involves molecular cloning, long DNA molecule extraction, bacterial culture and recombinant protein production and purification, with scope for some bioinformatic analysis. Based in a well-equipped Oxford lab, collaborating on translation of synthetic chloroplast genomes into crop plants such as potato and wheat.

DNA Methylases

• Cambridge
• Senior

Leads stem cell-focused drug discovery projects, designing and optimising human iPSC-derived models, 2D/3D assays and disease models, and applying New Approach Methodologies to client programmes. Partners directly with pharmaceutical and biotech clients, presenting data and shaping project strategy, while mentoring colleagues and contributing to proposals and capability development.

Organoids · Spheroid systems · Co-culture models +4

• Oxford
• Hybrid
• Senior

Perform bioanalytical assays using molecular and cellular techniques such as ddPCR, qPCR, RT-qPCR and gel electrophoresis to quantify RNA in biological matrices. Support phase-appropriate assay development, qualification and validation within a GCLP-compliant clinical framework, partnering with internal and external labs and cross-functional teams. The role blends basic science research, bioanalysis and clinical development, with exposure to digital and automation tools.

Droplet Digital PCR · qPCR · RT-qPCR +2

• Harrow
• Remote
• Senior

Monitors clinical trial sites across the UK as the sole point of contact, conducting qualification, initiation, monitoring and termination visits and producing visit reports. Manages site quality, regulatory documentation and drug accountability while developing recruitment strategies to meet enrolment timelines. Fully decentralised role with less travel and a lower protocol load than industry peers.

Clinical Trial Management System · Electronic Document Management System · Excel +1

• Oxford
• Hybrid · 3–4 days in office
• Senior
• Permanent

Develops, validates and runs ligand-binding and cell-based bioanalytical assays generating pharmacodynamic and immunogenicity data for clinical mRNA programmes. Works in a GcLP-regulated lab using Thermo Watson LIMS and electronic notebooks, handling clinical samples, critical reagents, SOPs and validation reports while partnering with Clinical Operations and Sample Management.

Thermo Watson LIMS · Watson LIMS · LabVantage eLBN +1

• London
• Remote
• Senior

Responsible for the successful delivery of clinical studies at assigned investigator sites, acting as the primary point of contact for site management, monitoring, and study execution. Leads site preparation, initiation, routine monitoring, and close-out, conducting onsite and remote visits, source data review and verification, and CRF review while managing risk-based quality and regulatory compliance. Works within a local study team supporting a key sponsor, with travel across the UK and internationally.

CTMS · eTMF

• Addlestone
• £40,056 pa
• Mid-level
• Permanent

Design and execute scientific investigations into mammalian viral pathogenesis and host-pathogen interactions, ensuring work meets ISO9001, budget and customer requirements. Communicate findings via conferences and peer-reviewed journals, supervise staff and students, and pursue national and international research funding. Includes rostered on-call cover for weekend and Bank Holiday diagnostics.

ISO 9001

• Sheffield
• £32,722 – £37,369 pa
• Senior
• Contract

You will process samples for molecular and genomic analysis, maintain laboratory equipment, and support visiting researchers in a Genomics Laboratory. The role also involves training users new to molecular biology, advising external clients, and contributing to research and development that expands the facility's capabilities.

eDNA

• Reading
• Senior

Monitors clinical trial sites across the UK, handling selection, initiation, monitoring and close-out visits in line with GCP and ICH guidelines. Manages multiple protocols, drives subject recruitment, tracks regulatory submissions and CRF data, and maintains Trial Master File documentation. Based in Reading with regular travel to investigative sites.

• London
• Permanent

Builds and scales generative and predictive models of cellular behaviour, acting as the bridge between ML theory and implementation. Day to day involves optimising large neural networks, distributed multi-GPU training, profiling GPU workloads, and productionising research code for multi-modal biological data.

PyTorch · CUDA · Triton +3