Biotechnology Jobs

• Macclesfield
• On-site
• Senior · manages people
• Permanent

Acts as the key analytical point of contact for clients, leading the transfer of commercial analytical methods across multiple laboratory sites and ensuring their robustness, performance and compliance for drug substances. Coordinates analytical activities, supports change programmes and market access projects, and leads a small team of scientists while working with Quality, Regulatory and Manufacturing. Based at a pharmaceutical client facility in Macclesfield.

• Macclesfield
• On-site
• Permanent

Develops, optimises and validates trace analysis methods using LC-MS and Orbitrap technologies to detect and quantify trace-level small molecules in raw materials, intermediates and drug substances. Provides technical expertise on mutagenic impurities and nitrosamines at parts-per-billion levels, performing complex analytical investigations and authoring method development reports and validation protocols. Based at a client pharmaceutical facility, collaborating with multidisciplinary internal and external teams.

LC-MS · Orbitrap · GC-MS +6

• United Kingdom
• Remote
• Lead · manages people

Leads global regulatory strategy for Phase 1-4 clinical trials, preparing and assembling CTA submissions and acting as the client-facing liaison with sponsors and regulatory agencies. Represents the regulatory department in bid defense and launch meetings, managing project teams and reviewing clinical and scientific documentation.

Microsoft Word · Microsoft Excel · PowerPoint

• Oxford
• On-site
• Senior

Sole-contributor scientist role developing and executing biochemical and molecular biology assays for PK/PD analysis, spanning genomic DNA/RNA isolation, qPCR, ddPCR, RNA sequencing, MSD, ELISA and immunoblotting. Works within Moderna's Clinical Bioanalytical team at Harwell, Oxfordshire, ensuring GcLP-compliant assay qualification and validation, troubleshooting with external CRO partners, and building internal and external mRNA-based bioanalytical capability.

MSD · LIMS · eLNB +1

• United Kingdom
• Remote
• Mid-level

Independently manages basic project tasks including budgets, timelines and client correspondence, while supporting protocol and report development under senior supervision. Conducts qualitative data collection such as cognitive interviews and focus groups, performs literature reviews and data analysis, and assists with scientific publications. Requires 10-30% travel and works within a multidisciplinary patient-centered research team.

Microsoft Word · PowerPoint · Excel +5

• Exeter
• Entry level
• Contract

A cross-institutional PhD studentship analysing whole genome sequencing data from millions of individuals across UK Biobank, All of Us and Our Future Health to identify rare causal variants for musculoskeletal disorders, then functionally validating them in human cell and tissue models using CRISPR-Cas9, transcriptomics and cellular phenotyping. Split between computational genomics at Exeter and laboratory work at Oxford, it develops a dual skill set in statistical genetics and experimental validation.

UK Biobank · All of Us · Our Future Health +4

• Oxford
• On-site
• Senior

Provides hands-on MS&T engineering expertise across drug substance manufacturing and label, packaging and final-storage operations at the Harwell site. Leads technology transfer, process start-up, validation, continued process verification and troubleshooting, authoring protocols and reports as an individual contributor. Works cross-functionally with Manufacturing, Quality and Supply Chain, with on-call or shift coverage as required.

SAP · VEEVA · DeltaV +4

• United Kingdom
• £55,000 – £70,000 pa

This role involves leading in-vitro toxicology studies within a regulated preclinical environment, focusing on assay development and execution for product safety assessment. The scientist will apply advanced cell-based methods including Neutral Red, Ames, and micronucleus assays, interpret complex biological data, and support regulatory submissions. Collaboration with internal teams and external partners is key, alongside method validation and scientific reporting in a quality-assured laboratory setting.

• London
• Hybrid
• Senior

Oversees quality control testing for a genetically edited cell therapy, acting as lead point of contact for external CDMOs and QC labs on GMP release, stability and method lifecycle work. Leads OOS/OOT investigations, reference standards and assay controls programmes, authoring and approving SOPs, COAs and protocols. Hybrid role based in London requiring close collaboration with contract test labs and management on compliance risks.

LIMS

• Edinburgh
• Mid-level · manages people

Oversee a transgenic facility producing around 100 genetically modified animal models annually, advising researchers on project design and methodologies. Lead and develop three specialist technical staff while managing cryobanks, budgets, cost-recovery and regulatory compliance. The role combines hands-on molecular biology and transgenesis expertise with operational leadership in a university-linked biomedical research setting.

• Exeter
• £21,805 pa
• Entry level
• Contract

A PhD studentship developing and applying multiplexed Variable Dose Analysis (mVDA) to map genetic interactions in human cells, adapting the technology from Drosophila. The student will integrate mVDA with live-cell microscopy or single-cell sequencing and apply the platform to investigate NF1-associated gene networks, working across functional genomics, imaging, bioinformatics and statistics.

CRISPR · mVDA · Drosophila

• Oxford
• On-site
• Permanent

Designs and runs experiments on photosynthesis, carbon assimilation and yield-related pathways, using gas exchange, chlorophyll fluorescence and field work to assess plant physiology under varied conditions. Works in an interdisciplinary team on a stage-gated plant engineering programme, developing protocols and translating results into publications, IP and commercial opportunities.

• Oxford
• On-site
• Mid-level
• Permanent

Designs and runs evolution campaigns and selection schemes to optimise photosynthetic proteins, applying genome editing, directed evolution and protein engineering within a stage-gated plant engineering programme. Works in an interdisciplinary team translating photosynthesis, carbon fixation and yield findings into commercial and IP opportunities.

• Salt Lake City, United States
• Mid-level
• Contract

Develop, optimize and validate cell-based and biochemical assays for automated high-throughput screening, running workflows at scale across 384- and 1536-well formats. Work in a cross-disciplinary team with biologists, automation and data scientists, documenting methods so assays transfer reliably. A 9-month contractor role, Monday to Friday, 9am-5pm.

Liquid Handlers · Plate Readers · Imagers +5

• London
• On-site
• £47,500 pa
• Entry level
• Contract

Lead a research project investigating how cortical cell types respond to 3D visual stimuli, using multiphoton calcium imaging in virtual reality, correlative in situ sequencing and molecular connectomics. Combines systems and molecular neuroscience approaches, with responsibility for experiment design, data analysis in Python or MATLAB, and supervising junior staff.

Python · MATLAB