Jobs in Cambridge

Research Leader / Senior Scientist (Medicinal Drug Design), Cambridge, MA

Lead or contribute to drug discovery projects at the intersection of medicinal chemistry and AI, guiding programs from initiation to candidate selection. Collaborate closely with machine learning scientists to refine AI-driven drug design models and drive innovation in synthetic organic chemistry. Play a key role in shaping next-generation therapeutic development through strategic input, CRO management, and intellectual property generation.

Isomorphic Labs Cambridge, United Kingdom

Research Leader / Senior Scientist (Computational Drug Design), Cambridge, MA

Lead or contribute to drug discovery programs using AI-first approaches, integrating computational chemistry with machine learning to design novel therapeutics. Guide project strategy from hit identification through candidate selection, while collaborating closely with ML scientists and cross-functional teams. Help shape and refine AI models for drug design, with opportunities to lead teams and drive innovation in a dynamic, interdisciplinary environment.

Isomorphic Labs Cambridge, United Kingdom

Executive Medical Director, Clinical Development Lead - Oncology GU

This role involves leading the clinical development of oncology drugs, specifically in genitourinary cancers. Responsibilities include defining clinical strategies, leading governance discussions, and representing the company in health authority interactions. The role emphasizes data-driven decision-making and leveraging advanced analytics to enhance clinical development.

GSK United States

Executive Medical Director, Clinical Development Lead - Oncology GU

This role involves leading the clinical development of oncology drugs, specifically in genitourinary cancers. Responsibilities include defining clinical strategies, leading governance discussions, and representing the company in health authority interactions. The position requires strong scientific and leadership skills, with a focus on leveraging data and technology to drive clinical development.

GSK

Medical Director Clinical Development- Aging

This role involves leading clinical development for aging-related therapies within GSK’s Respiratory, Immunology & Inflammation Research Unit. The Medical Director will design and execute clinical development plans, provide medical oversight, and integrate translational and clinical data to advance drug candidates. The position emphasizes cross-functional leadership, regulatory engagement, and innovation in trial design to deliver differentiated medicines.

GSK £189,750 – £316,250 pa

Clinical Development Medical Director- Hepatology

Lead clinical development strategy and execution for hepatology assets within GSK’s Respiratory, Immunology & Inflammation Research Unit. Provide medical oversight across translational and clinical studies, design development plans and protocols, and guide decision-making for early-phase programs. Work cross-functionally to advance novel liver disease treatments from discovery through clinical proof of concept, leveraging biomarker and real-world data to inform development.

GSK United Kingdom US$202,500 – US$337,500 pa

Hybrid Permanent

Clinical Development Medical Director- Hepatology

Lead clinical development strategy and execution for hepatology programs, designing and overseeing translational and clinical studies to advance novel liver disease treatments. Provide medical leadership across cross-functional teams, contribute to regulatory interactions, and drive innovation in drug development. Focus on identifying high-impact targets and delivering differentiated medicines with strong scientific and clinical foundations.

GSK £202,500 – £371,250 pa

Hybrid Permanent

Clinical Development Medical Director- Hepatology

Lead clinical development strategy and execution for hepatology assets within GSK’s R&D pipeline, driving early-phase programs from target identification through proof of concept. Provide medical oversight, design translational studies, and guide cross-functional teams to deliver innovative therapies for liver disease with a focus on scientific rigor and patient impact.

GSK

Hybrid Permanent

Director, Real World Data Strategy and External Partnerships Lead

This role involves leading the strategic execution of external data partnerships to enhance R&D and CPO activities at GSK. Responsibilities include defining and delivering RWD partnerships, ensuring data quality, and fostering relationships with academic institutions, health technology companies, and health systems to support regulatory approval and research.

GSK

Antibody Discovery Scientist

This role involves leading the design and execution of experiments for antibody and protein discovery, using yeast-based and phage display platforms, in silico design tools, and other innovative technologies. The scientist will work in a lab-centric environment, contributing to the development of therapeutic antibodies and proteins, and collaborating with matrix teams on various disease targets.

GSK Stevenage, United Kingdom

Director - Diagnostic Execution (Oncology Translational Medicine)

This role involves leading the operational delivery of biomarker and diagnostic strategies for GSK's oncology portfolio, particularly focusing on Antibody Drug Conjugate (ADC) development. Responsibilities include managing a team, overseeing external testing partners, and ensuring regulatory compliance and successful drug-diagnostic co-development.

GSK Stevenage, United Kingdom

Antibody Discovery Associate Scientist

This role involves working in a lab-centric environment, focusing on antibody discovery and engineering using yeast-based and phage display platforms, combined with in silico design tools. The position offers opportunities to develop skills in molecular biology, AI-driven protein design, and collaboration within a dynamic team of experts.

GSK Stevenage, United Kingdom

Director - Diagnostic Execution (Oncology Translational Medicine)

This role involves leading the operational delivery of biomarker and diagnostic strategies for GSK's oncology portfolio, particularly focusing on Antibody Drug Conjugate (ADC) development. Responsibilities include managing a team, overseeing external testing partners, and ensuring regulatory compliance and successful drug-diagnostic co-development.

GSK

Manager / Associate Director - Global Regulatory Strategy (Respiratory, Immunology & Inflammation)

This role involves developing and executing global and regional regulatory strategies for respiratory, immunology, and inflammation products. Key responsibilities include managing regulatory interactions, ensuring compliance with internal and external requirements, and collaborating with global and regional teams.

GSK

Manager / Associate Director - Global Regulatory Strategy (Respiratory, Immunology & Inflammation)

This role involves developing and executing global and regional regulatory strategies for respiratory, immunology, and inflammation products. Key responsibilities include managing regulatory interactions, ensuring compliance with internal and external requirements, and collaborating with global and regional teams.

GSK United Kingdom