Latest Drug Discovery Jobs

Research Leader (DMPK), Cambridge, MA

Lead DMPK strategy for drug discovery projects using an AI-first approach, integrating quantitative pharmacology and ADME data to guide candidate selection. Collaborate with chemistry, pharmacology, and machine learning teams to optimise molecule design and advance predictive models. Contribute to regulatory documentation and drive innovation in human PK prediction and biotransformation understanding.

Isomorphic Labs Cambridge, United Kingdom

Research Leader (Toxicology), Cambridge, MA

This role involves leading toxicology strategy in drug discovery with an AI-first approach, designing safety assessment frameworks, and guiding the development of predictive AI models for toxicity. The candidate will work across small molecules and biologics, collaborate with machine learning teams, oversee outsourced wet-lab studies via CROs, and mentor junior scientists. A key focus is reducing reliance on animal testing through innovative, data-driven toxicology solutions.

Isomorphic Labs Cambridge, United Kingdom

Executive Director, Asset Team Lead

The Executive Director, Asset Team Lead, will drive the strategic positioning of clinical assets in oncology and immunology, leveraging Recursion's proprietary OS and ClinTech insights. This role involves cross-functional collaboration to ensure the advancement of transformative medicines, with a focus on competitive positioning and patient benefit.

Recursion United Kingdom

Executive Director, Clinical Pharmacology/Pharmacometrics

This role involves leading clinical pharmacology and pharmacometrics strategies for rare disease and oncology programs, designing clinical studies, and interfacing with regulatory authorities. The position requires extensive experience in drug development, proficiency with modeling software, and collaboration with cross-functional teams.

Recursion United Kingdom

Executive Medical Director, Clinical Development Lead - Oncology GU

This role involves leading the clinical development of oncology drugs, specifically in genitourinary cancers. Responsibilities include defining clinical strategies, leading governance discussions, and representing the company in health authority interactions. The role emphasizes data-driven decision-making and leveraging advanced analytics to enhance clinical development.

GSK United States

Executive Medical Director, Clinical Development Lead - Oncology GU

This role involves leading the clinical development of oncology drugs, specifically in genitourinary cancers. Responsibilities include defining clinical strategies, leading governance discussions, and representing the company in health authority interactions. The position requires strong scientific and leadership skills, with a focus on leveraging data and technology to drive clinical development.

GSK

Principal Scientist, Bioanalytical & Molecular Assays

Lead the development and validation of molecular assays including RT-qPCR, dPCR, and NGS for clinical biomarker programs across Moderna's therapeutic pipeline. Drive end-to-end assay lifecycle management, ensure regulatory compliance with GCLP standards, and collaborate with cross-functional teams to deliver high-quality genomic data. Mentor scientists and integrate advanced analytics and AI-enabled tools to accelerate discovery and translational research.

Moderna Oxford, United Kingdom

Hybrid Permanent

Principal Scientist, Bioanalytical & Molecular Assays

This role involves leading the development and validation of advanced molecular assays—including RT-qPCR, dPCR, and NGS-based methods—for clinical biomarker programs at Moderna. The scientist will drive end-to-end assay lifecycle management, ensure compliance with GCLP and regulatory standards, and collaborate across multidisciplinary teams to generate high-quality genomic data. A key focus is integrating genomics, bioinformatics, and clinical insights to support drug development and inform future pipeline strategies.

Moderna

Hybrid Permanent

Associate Manager (Pharmaceutical Development)

This role involves leading and managing a team of scientists in the development of inhalation and respiratory drug products. Responsibilities include providing technical expertise, mentoring team members, and ensuring project success and regulatory compliance.

Smart4Sciences Cwmbran, Gwent, United Kingdom

Embedded Software Engineer - Medical Devices

This role involves developing embedded C and C++ software for medical devices, ranging from lab and hospital equipment to personal use sensors. You will work through all project stages, from concept to manufacture, and interact closely with clients and team members.

ECM Selection Cambridge, Cambridgeshire, United Kingdom £45,000 – £55,000 pa

TCTU Portfolio Trial Manager (BE-GENOMICS)

This role involves managing clinical trials, including providing support on approval processes, trial management, recruitment strategies, and data quality. The position is part of the Tayside Clinical Trials Unit (TCTU) and focuses on both new and established drug and complex intervention trials, with a lead role in the BE-Genomics trial.

University of Dundee Dundee, United Kingdom £37 – £46 pa

On-site Contract Part-time

Associate Director, Statistical Programming

Lead a global team of statistical programmers, driving standardization, innovation, and quality in clinical trial data analysis. Develop programming strategies using modern tools like R, Git, and AI-enabled technologies, ensuring audit-ready deliverables and alignment with biostatistics and data management. Provide technical leadership and influence global drug development strategy across phases I–IV studies.

Novartis London, United Kingdom £67,900 – £126,100 pa

Hybrid Permanent

Senior Postdoctoral Immunologist

This role involves conducting advanced immunological research on vaccine responses, using techniques like flow cytometry, cell culture, and single-cell RNA sequencing. You will work independently, manage data, and train junior team members in a leading research group.

University of Oxford Oxford, South East England, United Kingdom £49 – £58 pa

Contract

Innovation Capability Director - Global Clinical Operations (GCO)

This role involves leading the identification, implementation, and scaling of innovative patient recruitment solutions for clinical trials. The director will work with global teams and technology partners to improve clinical trial participation, focusing on digital marketing and AI-driven approaches.

Novartis London, United Kingdom

Associate Operator / Operator I

This hands-on manufacturing role involves executing production processes in a GMP cleanroom environment, operating cell-processing equipment, and maintaining cleanroom standards. The role supports continuous improvement and quality assurance, with a focus on delivering autologous cell therapy products.

Autolus Stevenage, United Kingdom