Latest Clinical Research Associate Jobs

Senior SDTM Statistical Programmer

Technical lead on assigned clinical studies, shaping SDTM strategies from protocol review through to global regulatory submission. Involves root cause analysis, cross-functional collaboration, data integration from CRF and non-CRF sources, and engagement with SDTM automation, metadata-driven processes and agentic AI workflows. Also provides quality oversight to team members and manages CRO and vendor programming activities.

Bristol Myers Squibb Uxbridge

Hybrid

Manager, CMC Documentation

Authoring and coordinating CMC sections of regulatory submissions (INDs, CTAs, NDAs, BLAs) across small molecules, biologics and ADCs, and leading specification activities for small molecules. The role involves verifying data, drafting responses to Health Authority inquiries and collaborating with development, manufacturing and regulatory teams. Distinct for its rare breadth across three molecule modalities and global regulatory exposure.

Bristol Myers Squibb Wirral

Hybrid

Principal Statistical Programmer

Lead statistical programming for clinical trials, turning complex data into submission-ready outputs using SAS, CDISC, and ADaM standards. Embedded in cross-functional teams, you'll review analysis plans, shape programming strategy, and mentor other programmers while supporting major regulatory filings.

Bristol Myers Squibb Uxbridge

Hybrid

Associate Director, CMC Regulatory Science - UK

Lead CMC regulatory strategy for UK-manufactured and UK-licensed mRNA products across development, registration and post-approval lifecycle. Act as primary point of contact with the MHRA, oversee CMC submissions and manufacturing change assessments, and shape global regulatory approaches. Based in London or Harwell with regular travel, working in a 70/30 in-office model.

Moderna Clinical Development

Hybrid Clearance Required

Associate Director, CMC Regulatory Science - UK

Lead CMC regulatory strategy for UK-manufactured and UK-licensed mRNA products across development, registration and post-approval lifecycle. Act as primary point of contact with the MHRA, oversee submissions and manufacturing change assessments, and guide cross-functional teams spanning Technical Development, Manufacturing, Quality and Commercial. Based in London or Harwell with a 70/30 in-office model.

Moderna Didcot

Hybrid Clearance Required

Maintenance Engineering Manager - Packaging

Lead the technical maintenance and engineering setup of a brand-new Label and Secondary Packaging operation at the Harwell site, from URS and FMEA through commissioning, qualification and validation. Develop preventative maintenance strategies, manage external vendors and build the site maintenance team, working with GMP equipment and digital/AI-enabled engineering tools.

Moderna Oxford

Senior Scientist

Drive innovation as a strategic consultant on high-impact drug discovery projects with external pharma and biotech partners. Navigate the full development pipeline from target discovery to patient stratification, applying statistical human genetics and large-scale genomic data analysis in R or Python. Partner-facing role translating complex findings into actionable insights.

Genomics London

Hybrid Permanent

Associate Director, Biostatistics

As a member of cross-functional development teams, you will contribute to trial design, protocol development, analysis planning, and regulatory submissions. The role involves authoring statistical analysis plans and clinical study reports, defending protocols at governance reviews, and providing statistical leadership on health authority requests. It requires 50% onsite presence in Uxbridge and offers the chance to support a specific asset indication.

Bristol Myers Squibb Uxbridge

Hybrid

Biostatistician II

Lead statistician role delivering analysis database creation, statistical analyses, and formatted tables and summaries with minimal oversight, while mentoring junior team members. Involves leading project teams, interacting directly with sponsors, developing statistical analysis plans and randomization schemes, and programming or validating statistical tables with a strong emphasis on efficacy endpoints using SAS.

Thermo Fisher Scientific United Kingdom

Remote

Principal Scientist, Process Engineering

Bridges internal science teams and external CDMOs to scale up small molecule and ADC drug substance processes. Reviews batch records, audits facilities, troubleshoots manufacturing issues and presents risk assessments to leadership. Covers the full range of chemical engineering unit operations with up to 20% international travel.

Bristol Myers Squibb Wirral

Hybrid

Senior Scientist (Solid-State Chemistry & Molecular Materials Science)

Lead solid-state science across drug product projects, focusing on complex amorphous and disordered systems for oral and inhaled medicines. Define critical molecularly driven material attributes, design lab experiments probing drug-excipient interactions, and translate mechanistic insight into control strategies. Combines hands-on characterisation with computational and data-driven approaches, partnering with formulators, engineers and biopharmaceutics experts.

AstraZeneca Macclesfield

Hybrid Permanent

Scientist, Assay Development (Contractor)

Develop, optimize and validate cell-based and biochemical assays for automated high-throughput screening, running workflows at scale across 384- and 1536-well formats. Work in a cross-disciplinary team with biologists, automation and data scientists, documenting methods so assays transfer reliably. A 9-month contractor role, Monday to Friday, 9am-5pm.

Recursion Salt Lake City, United States

Contract

Executive Director, Chemical Biology

Leads chemical biology strategy at a clinical-stage TechBio company, setting direction for chemical probe design and new modalities such as targeted protein degradation and molecular glues. Builds and mentors a team of chemists, manages internal and CRO partners, and partners with biology, computational drug design and data science to link multiomic maps of biology to targets. Blends hands-on chemical biology expertise with program and people leadership.

Recursion Salt Lake City, United States US$237,600 – US$284,900 pa

Hybrid

Head of Operations - Biologics, RNA & MMIC

Lead multidisciplinary operational teams across two sites, covering operations, engineering, facilities and site services. Drive continuous improvement, GMP and H&S compliance, facilities management, budgets and capital projects supporting biologics, RNA and medicines manufacturing. Senior leadership role shaping facility strategy and operational capability.

SRG Darlington £65,000 – £85,000 pa

Permanent

Regulatory Affairs Director

Leads cross-functional teams on major EU regulatory submissions (MAA, CTR, IVDR, CTA), health authority interactions with the EMA and national bodies, label negotiations and approvals. Owns the EU engagement strategy, briefing documents and regulatory strategy for oncology programmes, mentoring the Global Regulatory Strategy Team. Distinct for its focus on late-stage oncology assets and European approval pathways.

AstraZeneca Cambridge

On-site Permanent