Biotechnology Jobs

• Waltham, United States
• Hybrid · 2 days in office
• US$284,250 – US$473,750 pa
• Director · manages people

Leads a team of early clinical development medical directors and clinical scientists, owning Phase I/II clinical development plans including first-in-human, dose-escalation and proof-of-concept studies in lung and head/neck cancers. Bridges preclinical discovery and clinical development, driving translational and biomarker strategy, regulatory submissions and cross-functional matrix teams.

AI/ML

• Stevenage
• Hybrid · 2 days in office
• US$284,250 – US$473,750 pa
• Director · manages people

Leads a team of medical directors and clinical scientists designing and executing early-phase oncology trials, including first-in-human, dose-escalation and proof-of-concept studies, while bridging preclinical discovery and clinical development. Accountable for clinical development plans, benefit-risk, regulatory submissions and translational biomarker strategy across lung and head/neck cancer assets.

AI/ML

• USA - Pennsylvania - Upper Providence
• On-site
• US$222,750 – US$371,250 pa
• Director

Serves as the physician within oncology clinical programme teams for lung and head/neck cancers, leading medical monitoring, safety oversight and clinical data interpretation across Phase I–III studies. Partners with a Senior Scientist and cross-functional matrix teams on protocol development, regulatory interactions and investigator engagement, with on-site presence 2–3 days per week.

AI-enabled Insights

• USA - Pennsylvania - Upper Providence
• On-site
• US$284,250 – US$473,750 pa
• Director

Leads clinical development of GU oncology assets, designing and executing Phase 1-3 interventional trials and serving as a core member of the Clinical Matrix Team. Provides real-time medical monitoring, safety data review with pharmacovigilance, and authors clinical study reports and regulatory responses. Builds key external expert relationships and contributes to business development diligence.

• USA - Pennsylvania - Upper Providence
• Hybrid · 2 days in office
• US$189,750 – US$316,250 pa
• Director

Serves as the physician within a clinical program team, leading medical monitoring and safety oversight for genitourinary oncology studies. Interprets clinical and safety data, contributes to protocol development and regulatory interactions, and acts as a core member of the Clinical Matrix Team. May guide other physicians on complex multi-study programs.

AI

• USA - Pennsylvania - Upper Providence
• On-site
• US$284,250 – US$473,750 pa
• Director · manages people

Senior physician leader providing medical oversight, safety monitoring and clinical data interpretation across sarcoma oncology studies, from protocol design through regulatory interactions. Serves as a senior member of the Clinical Matrix Team, mentoring Medical Directors and engaging external experts, advisory boards and health authorities.

Real World Evidence (RWE)

• USA - Pennsylvania - Upper Providence
• Hybrid · 2 days in office
• US$242,250 – US$403,750 pa
• Director · manages people

Accountable for end-to-end clinical development strategy for an antibody-drug conjugate asset across multiple tumour types, from first-in-human through registrational trials and launch. Acts as senior clinical representative at governance forums and leads cross-functional, matrixed teams spanning research, precision medicine, medical affairs and commercial.

• Waltham, United States
• Hybrid · 2 days in office
• US$222,750 – US$371,250 pa
• Director

Serves as the physician on a clinical program team, leading medical monitoring, safety oversight and data interpretation for oncology and hematology studies. Partners with a Senior Scientist and cross-functional groups on protocol development, regulatory interactions and investigator engagement within a matrix team. May guide other physicians on complex multi-study programs.

AI

• Stevenage
• Hybrid · 2 days in office
• Director

Serves as the physician on a clinical program team, leading medical monitoring and safety oversight for oncology and hematology studies. Interprets clinical and safety data, contributes to protocol development and regulatory interactions, and acts as a core member of the Clinical Matrix Team. May mentor other physicians on complex multi-study programs.

AI

• London
• Hybrid · 2 days in office
• Director

Serves as the physician on a clinical program team, leading medical monitoring and safety oversight for oncology and hematology studies. Interprets clinical and safety data, contributes to protocol development, and engages investigators, regulators and cross-functional matrix teams. May guide other physicians on complex multi-study programs.

AI

• Mississauga, Canada
• Hybrid · 2 days in office
• US$222,750 – US$371,250 pa
• Director

Serves as the physician on a clinical program team, leading medical monitoring and safety oversight for oncology and hematology studies. Interprets clinical and safety data, contributes to protocol development, and engages with investigators, regulators, and cross-functional matrix teams. May guide other physicians on complex multi-study programs.

AI

• USA - Pennsylvania - Upper Providence
• Hybrid · 2 days in office
• US$222,750 – US$371,250 pa
• Director

Serves as the physician within oncology clinical program teams, leading medical monitoring, safety oversight, and clinical data interpretation across studies. Partners with Senior Scientists and cross-functional matrix teams on protocol development, regulatory interactions, and investigator engagement. May guide other physicians on complex multi-study programs within the clinical strategy set by the Clinical Development Lead.

AI

• Baar Onyx
• Hybrid · 2 days in office
• US$222,750 – US$371,250 pa
• Director

Serves as the physician within oncology clinical program teams, leading medical monitoring, safety oversight and clinical data interpretation for hematology studies. Partners with a Senior Scientist and cross-functional matrix teams on protocol development, regulatory interactions and investigator engagement, with hybrid working at least two days on-site.

AI

• Stevenage
• Hybrid
• £119,250 – £198,750 pa
• Director

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late pre-candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work across small molecules, biologics and antibody drug conjugates, applying AI/ML and quantitative systems pharmacology methods. Presents and defends modelling outcomes to governance boards and regulators, and contributes to protocols, analysis plans and submissions.

NONMEM · R

• Waltham, United States
• Hybrid
• £188,100 – £313,500 pa
• Director

Leads model-informed drug development for oncology programs, defining and executing model-based strategies from late discovery through lifecycle management. Conducts population PK, exposure-response, simulation-based trial design and dose selection, applying AI/ML, quantitative systems pharmacology and model-based meta-analysis. Presents to governance boards and regulators and works across matrix teams on small molecules, biologics and antibody drug conjugates.

NONMEM · R