Biotechnology Jobs

GSK · Baar Onyx · US$222,750 – US$371,250 pa

Serves as the physician within oncology clinical program teams, leading medical monitoring, safety oversight and clinical data interpretation for hematology studies. Partners with a Senior Scientist and cross-functional matrix teams on protocol development, regulatory interactions and investigator engagement, with hybrid working at least two days on-site.

GSK · USA - Pennsylvania - Upper Providence · £174,750 – £291,250 pa

Leads respiratory epidemiology and real-world evidence programs that inform vaccine development, accountable for at least one asset or disease area and its Global Epidemiology Plan. Designs and oversees complex observational studies using claims, EHR and registry data, advises clinical, safety and regulatory matrix teams, and manages external partnerships and scientific dissemination. Also mentors junior epidemiologists and represents the company with regulators and at international conferences.

GSK · Durham, United States · US$188,100 – US$313,500 pa

Leads end-to-end application of Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Partners with digital medicine, translational imaging, modelling and biostatistics teams, and drafts regulatory content for FDA, EMA, CDE, PMDA and ICH submissions. Based in the newly formed Clinical Pharmacology and Quantitative Medicine organisation, with a strong publication and scientific leadership remit.

GSK · Stevenage

Leads Quantitative Systems Pharmacology and QST modelling within GSK's Clinical Pharmacology and Quantitative Medicine group, building mechanistic mathematical models of disease, drug action and trial design. Defines clinical pharmacology strategy across the Respiratory, Immunology and Inflammation portfolio, working with biologists, clinicians, statisticians and AI/ML colleagues. The role sits in a newly formed Centre of Excellence for Model-Informed Drug Development, initially in Stevenage with a planned move to Cambridge.

GSK · Grimsby · US$188,100 – US$313,500 pa

Leads quantitative systems pharmacology and QST modelling within a clinical pharmacology and quantitative medicine group, building mechanistic models of disease and drug action and running simulations to inform trial design. Defines and coordinates MIDD strategies across respiratory, immunology and inflammation programmes, working with biologists, clinicians, pharmacometricians and statisticians. Combines inverse-problem modelling, scientific ML and statistical methods to support decisions from exploratory research through clinical development.

GSK · London

Leads GSK's Forward Deployed Engineering function for CMC R&D, setting strategy, hiring and mentoring engineers, and owning senior BU sponsor relationships. Personally contributes to strategic engagements building digital twins, physical AI and self-driving lab capability, using AI coding agents as the primary development mode.

GSK · USA - Pennsylvania - Upper Providence · US$189,750 – US$316,250 pa

Leads the design and execution of clinical biomarker and translational medicine strategies for late-stage oncology assets, defining patient segmentation and decision criteria within Clinical Matrix Teams. Validates predictive, pharmacodynamic and resistance biomarkers using platforms such as NGS, ctDNA, flow cytometry and multi-omic analyses to inform dose selection and go/no-go decisions.

GSK · London · US$189,750 – US$316,250 pa

Leads the design and execution of clinical biomarker and translational medicine strategies for late-stage oncology assets, defining patient segmentation and decision criteria within Clinical Matrix Teams. Oversees biomarker assay development, sample testing plans and data packages across platforms such as NGS, IHC, flow cytometry and ctDNA, working with internal and external partners.

GSK · Baar Onyx · US$222,750 – US$371,250 pa

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Coordinates CPMS activities across assets, approves study designs and regulatory documents, and partners with digital medicine, translational imaging and modelling specialists. Reports into the Respiratory, Immunology & Inflammation Research Unit within the new CPQM organisation.

GSK · USA - Pennsylvania - Upper Providence · US$222,750 – US$371,250 pa

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Coordinates CPMS activities across assets, approves study designs and regulatory documents, and partners with digital medicine, translational imaging, biostatistics and AI/ML teams. Sits in the newly formed Clinical Pharmacology and Quantitative Medicine organisation, reporting into the Respiratory, Immunology & Inflammation Research Unit.

GSK · Baar Onyx · US$188,100 – US$313,500 pa

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Sits in the Clinical Pharmacology and Quantitative Medicine organisation, partnering with digital medicine, translational imaging, modelling and biostatistics teams, and drafting regulatory content for FDA, EMA and ICH submissions.

GSK · USA - Pennsylvania - Upper Providence · US$188,100 – US$313,500 pa

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Designs MIDD and ClinPharm evidence strategies, drafts regulatory content for FDA, EMA, CDE, PMDA and ICH, and partners with digital medicine, translational imaging, modelling and data science teams. Sits in the newly formed Clinical Pharmacology and Quantitative Medicine organisation.

GSK · USA - Pennsylvania - Upper Providence · US$188,100 – US$313,500 pa

Leads quantitative systems pharmacology and QST modelling within a clinical pharmacology and quantitative medicine group, building mechanistic mathematical models of disease and drug action to inform trial design and MIDD strategy. Collaborates with biologists, clinicians, pharmacometricians and AI/ML teams, and represents the function on internal advisory boards.

GSK · London · US$188,100 – US$313,500 pa

Leads quantitative systems pharmacology and QST modelling within a clinical pharmacology and quantitative medicine group, building mechanistic models of disease and drug action and running simulations to inform trial design. Defines and coordinates MIDD strategies across respiratory, immunology and inflammation programmes, working with biologists, clinicians, pharmacometricians and AI/ML specialists. The role sits in a newly formed centre of excellence and involves representing QSP on internal advisory boards.

GSK · Durham, United States · US$188,100 – US$313,500 pa

Leads quantitative systems pharmacology and QST modelling within a clinical pharmacology and quantitative medicine group, building mechanistic models of disease and drug action and running simulations to assess trial design. Defines and coordinates MIDD strategies across respiratory, immunology and inflammation programmes, working with biologists, clinicians, pharmacometricians and AI/ML specialists. The role sits in a newly established Centre of Excellence for model-informed drug development.