413 jobs for “Operational Excellence”
Lead and develop a global regulatory team delivering clinical trial submissions and approvals, combining people leadership with regulatory expertise. Drive process improvement, simplification and automation while building stakeholder partnerships across Regulatory Affairs. Hybrid role with remote option for UK candidates over 50 miles from the London office.
Lead and develop a global regulatory team delivering clinical trial submissions and approvals, combining people leadership with regulatory expertise. Drive process improvement, simplification and automation while building stakeholder partnerships across Regulatory Affairs. Hybrid or remote working within the UK, with occasional office presence in London.
Moderna · 1001–5000 people · Late stage
Perform bioanalytical assays using molecular and cellular techniques such as ddPCR, qPCR, RT-qPCR and gel electrophoresis to quantify RNA in biological matrices. Support phase-appropriate assay development, qualification and validation within a GCLP-compliant clinical framework, partnering with internal and external labs and cross-functional teams. The role blends basic science research, bioanalysis and clinical development, with exposure to digital and automation tools.
Droplet Digital PCR · qPCR · RT-qPCR +2
IQVIA
Leads complex global and multi-regional clinical trials from start-up through close-out, with accountability for quality, timelines, budgets, regulatory compliance and sponsor objectives. Acts as primary strategic partner to sponsors and directs cross-functional teams across regions, with a focus on renal, obesity and MASH studies.
Parexel
Lead monitoring activities for assigned oncology clinical trial sites, from site activation through closeout, conducting both onsite and remote visits, source data verification and regulatory document oversight. Partner with a dedicated sponsor in an FSP model, driving enrollment, resolving protocol deviations and supporting audit readiness. Requires at least five years of oncology clinical research experience and up to 75% travel.
CTMS · EDC
Moderna · 1001–5000 people · Late stage
Support assay development, qualification, validation and clinical sample testing within Moderna's Immunoassay group, generating bioanalytical data that informs clinical trials. Work is primarily lab-based (≥85% of time) under a study lead, with responsibility for data integrity, reagent preparation, equipment upkeep and compliance with GCP/ISO standards.
GraphPad Prism · LIMS · Word +2
GSK · 10000+ people · Public
Leads end-to-end clinical development of hematology oncology assets from first-in-human studies through registrational trials, regulatory approval and launch. Sets disease-area strategy, chairs governance forums and scientific advisory boards, and line-manages clinical development leads and medical directors within a global matrix team.
AI/ML
GSK · 10000+ people · Public
Leads end-to-end clinical development of hematology oncology assets from first-in-human studies through registrational trials, regulatory approval and launch. Provides portfolio oversight, chairs governance forums and scientific advisory boards, and line-manages Clinical Development Leads and Medical Directors within a global matrix team.
AI/ML
IQVIA
Oversees vendor activities across global clinical trials from study start-up through close-out, managing central lab, eCOA, IRT, ECG, imaging and patient recruitment vendors. Tracks vendor performance, KPIs and KQIs, drives site readiness and activation, and handles risk mapping, contingency planning and cost control. Home-based within Europe, working in a single-sponsor department.
eCOA · IRT · ECG +1
Autolus · 101–500 people · Series C
Serves as the primary point of contact for Advanced Therapy Treatment Centres across South UK, driving appropriate utilisation of CAR T therapies and coordinating site qualification, setup and patient treatment logistics. Works cross-functionally with Marketing, Medical Affairs and Market Access, and is 80% field based with UK travel.
Autolus · 101–500 people · Series C
Accountable for onboarding and ongoing performance management of apheresis and treatment centres supporting clinical and commercial CAR T-cell therapies across the UK and Rest of World. Serves as the technical operations single point of contact, conducting site assessments, training centre staff, supporting quality systems and deviations, and managing process change rollouts. Involves up to 50% travel and possible management of contract employees.
Electronic Data Management Systems
Leads a global team of development and regulatory project managers overseeing complex R&D programs across a therapeutic area, including new product development and life cycle management. Drives portfolio planning, risk assessment, and cross-functional alignment as part of the Portfolio & Operations Excellence leadership team, with hands-on coaching and process improvement.
Microsoft Project · Planview · Smartsheet +1
Pfizer · 10000+ people · Public
Conduct strategic regulatory activities for assigned products and markets, managing Marketing Authorisation applications, variations, renewals and NRA queries. Work with cross-functional teams and above-country hubs to maintain compliance, support clinical trial applications and share regulatory intelligence.
Agilent
Lead a team of software engineers delivering next-generation Raman spectroscopy software from the Laser Spectroscopy Center of Excellence in Oxford (Harwell). The role owns R&D operations across the software product lifecycle, solving engineering challenges and integrating hardware and software with global partners, using modern architectures such as containerisation, Kubernetes, microservices and cloud deployment.
Kubernetes · Linux · Microsoft
Ellison Institute of Technology · 501–1000 people · Non-profit
Supports the smooth operation of research laboratories through cleaning, equipment maintenance, calibration and inventory management of reagents and consumables. Acts as point of contact for external servicing visits, handles and transports biological samples, and helps maintain health and safety compliance including waste disposal and temperature-sensitive storage.
