Latest Drug Discovery Jobs

Director, Regulatory Affairs

Lead the development and execution of global regulatory strategies for drug discovery programs, ensuring compliance across jurisdictions including the US, UK, and EU. Collaborate with cross-functional teams to manage regulatory submissions, engage with health authorities, and support clinical development from IND-enabling stages through approval and lifecycle management. Drive regulatory innovation by applying AI-driven platforms to accelerate drug development pathways.

Recursion United Kingdom £111,100 – £141,800 pa

Manager, Computational Biology (Early Oncology)

Lead a team of computational biologists to integrate multi-omics data for oncology target discovery and validation, while actively contributing to data analysis and cross-functional decision-making. Develop biomarker strategies and patient stratification approaches to guide therapeutic development. Collaborate closely with biologists, chemists, and clinical teams to advance drug programs using high-dimensional datasets and scalable computational methods.

Recursion United Kingdom US$151,800 – US$230,000 pa

Hybrid Permanent

Senior Scientist (In vitro / Cellular Pharmacology), Cambridge, MA

This role involves designing and executing biological screening cascades to validate computational predictions in drug discovery. The scientist will lead biophysical, biochemical, and cellular assay development, collaborate with CROs, and bridge AI-driven insights with experimental validation across oncology and immunology programs. Close collaboration with medicinal chemistry, structural biology, and machine learning teams ensures data informs rational drug design.

Isomorphic Labs England

Hybrid Permanent

Senior Scientist (In vivo Pharmacology & Translational Sciences), Cambridge, MA

Lead translational strategies for oncology and immunology programs by designing in vivo pharmacology and PK/PD studies to validate AI-designed drug candidates. Bridge computational predictions with experimental validation through CRO partnerships and biomarker-driven approaches. Drive preclinical data generation to inform clinical trial design and regulatory filings.

Isomorphic Labs England

Hybrid Permanent

Translational Science Lead

Leads end-to-end translational strategies for respiratory disease programmes, integrating human biology, multi-omics data, and biomarker development to de-risk clinical decisions. Designs and implements target validation, patient stratification, and precision medicine approaches while collaborating across discovery, clinical, and data science teams. Drives biomarker strategy into clinical protocols and regulatory submissions, using AI/ML and innovative assays to generate actionable insights.

AstraZeneca Cambridge, United Kingdom

Associate Principal Scientist, AI and Computational Tools, Oncology R&D (1-year

This role involves designing and deploying AI-powered tools and computational workflows to accelerate oncology drug discovery, with a focus on immuno-oncology. The scientist will build scalable data infrastructure, develop agentic AI and LLM-integrated solutions, and act as a technical leader across dry-lab and wet-lab teams. The position emphasizes translating complex biological data—such as single-cell and spatial transcriptomics—into reproducible, insight-generating systems while mentoring others in AI adoption and best practices.

AstraZeneca Cambridge, United Kingdom

On-site Contract

Principal Scientist, Translational Omics

This role involves leading the analysis and integration of multi-omic data—including single-cell and spatial transcriptomics, proteomics, and metabolomics—to generate actionable insights for drug development. The scientist will work across therapeutic areas with a focus on hepatology, renal, metabolic, and cardiovascular diseases, supporting target identification, biomarker discovery, and patient stratification. The position emphasizes innovation in computational methods, collaboration in cross-functional teams, and scientific impact through publications and pipeline contributions.

GSK United States €74,250 – €123,750 pa

Principal Scientist, Translational Omics

This role involves leading the analysis and integration of complex multi-omic datasets—including single-cell and spatial transcriptomics, proteomics, and metabolomics—to generate actionable biological insights that inform drug development decisions. The scientist will work across hepatology, renal, metabolic, and cardiovascular disease areas, applying advanced computational and statistical methods to support target identification, biomarker discovery, and patient stratification. Collaboration with cross-functional teams and external partners is central, with an emphasis on reproducible, scalable code and scientific innovation.

GSK €74,250 – €123,750 pa

Process Technician 11-Month

Operate and monitor manufacturing processes in a cGMP-regulated biopharmaceutical environment, supporting the production of life-changing medicines. Perform troubleshooting, contribute to process improvements using Lean methodologies, and assist in validation and documentation activities. Work within a rotating shift pattern in a safety-focused, highly regulated team setting.

Appcast Enterprise Dublin, Alba / Scotland, IV17 0YF, United Kingdom

Contract

PDRA in Molecular Biology - Grade 7

This role involves researching the mechanisms of antimicrobial drug resistance in bacteria and fungi, with a focus on mapping pathways to antifungal resistance development and designing strategies to counteract it. The researcher will work within a well-funded group focused on global health challenges related to antibiotic and antifungal resistance. Work will be conducted in a hybrid environment, combining lab-based molecular biology techniques with collaborative research activities.

University of Liverpool Liverpool, Northern England, United Kingdom £39 – £46 pa

Contract

Principal Scientist (Comp. Bio/ML) - Director Level

This role involves leading the scientific evaluation and application of foundation models in drug development and translational research. The individual will act as a key collaborator to research, product, and business teams, translating advanced biology and machine learning into practical customer solutions. Mentoring junior scientists and contributing to real-world discovery workflows are central to the position.

Helical London, United Kingdom

Hybrid Permanent

(Fixed Term) Scientist, Immunogenicity, Bioanalytical and Molecular Assays

This role involves designing and executing bioanalytical and immunogenicity strategies to support mRNA-based therapeutic development. The scientist will lead assay development for clinical programmes using platforms like ELISA, MSD, and cell-based methods, ensuring regulatory compliance and robust data generation. The position emphasizes collaboration across multidisciplinary teams and integration of digital tools and AI to advance Moderna's pipeline.

Moderna Oxford, United Kingdom

On-site Contract

(Fixed Term) Scientist, Immunogenicity, Bioanalytical and Molecular Assays

This role involves designing and executing bioanalytical and immunogenicity strategies to support mRNA-based clinical development programmes. The scientist will lead assay development—including ADA, nAb, PK, and PD assays—using platforms like ELISA, MSD, and cell culture, while ensuring regulatory compliance and contributing to Moderna's expanding capabilities in Harwell. The position emphasizes collaboration across multidisciplinary teams and integration of digital and AI-enabled tools to enhance data interpretation and decision-making.

Moderna

On-site

Software Engineer

Build and maintain scalable AI systems that integrate large language models with biomedical research tools, focusing on agent development, data workflows, and deployment within a multidisciplinary environment. Work on real-time, interactive systems that empower researchers through robust backend engineering and AI integration.

Owkin Paris, France

Remote Permanent

Senior / Principal Bioinformatician

Process and analyse multi-omic clinical datasets including RNAseq, NGS, and proteomics to derive biological insights supporting drug development decisions. Develop and optimise computational pipelines, integrate omics data with clinical variables, and contribute to scientific reporting and publications. Work autonomously within a collaborative, science-driven team across therapy areas such as oncology, neuro, and inflammation.

Hays Life Sciences London, United Kingdom