292 jobs for “Director Ta Portfolio Delivery Lead”
Leads strategic sourcing and evaluation of late-stage external clinical assets in Immunology, from Phase 2 through marketed drugs, as the senior S&E leader within the Therapy Area Leadership Team. Drives proactive sourcing, cross-functional due diligence, and KOL engagement, partnering with BD to advance high-priority opportunities through negotiation and deal close.
GSK · 10000+ people · Public
Leads the design and delivery of real-world evidence and health outcomes studies across oncology assets, managing protocols, budgets, timelines and vendor deliverables. Partners with medical, market access, R&D and commercial teams plus external experts to shape evidence for HTA submissions, reimbursement and value-based pricing. Requires deep knowledge of RWD sources and payer evidence requirements.
GSK · 10000+ people · Public
Leads the design and delivery of real-world evidence and health outcomes studies for oncology assets, managing protocols, budgets, vendors and reporting from concept to publication. Advises medical, market access and commercial teams on payer and HTA evidence needs, and builds relationships with external experts and data partners.
Leads the full statistical contribution to a clinical development programme, defining statistical strategy for trial design, analysis and regulatory submissions, and representing Biostatistics in interactions with the FDA, EMA and PMDA. Also manages outsourcing to CROs/FSPs and contributes to governance and development-plan decisions across therapeutic areas.
SAS · R
Acts as a QA liaison between clinical trial teams and third parties, providing expert support through due diligence, qualification, governance and ongoing monitoring. Focuses on technology-enabled vendors such as digital health tools, medical devices and AI, covering risk assessment, audit support, inspection readiness and escalation of quality issues.
DHT · SaMD · SaaS +1
Acts as the primary interface between business stakeholders, biostatisticians, statistical programmers and technical delivery teams, translating clinical and statistical requirements into scalable R-based analytics, automation workflows and enterprise reporting. Leads requirement workshops, manages a small team and oversees releases with end-to-end traceability, regulatory compliance and audit readiness across development, validation and deployment.
Bristol Myers Squibb
Owns the clinical strategy for one or more neuropsychiatry programs, serving as Clinical Trial Physician and clinical point of accountability for the Clinical Development Team. Leads trial design, data interpretation, regulatory submissions and health authority interactions, with matrix leadership across global scientific teams.
AstraZeneca · 10000+ people · Public
Leads an integrated Business Continuity and Crisis Management capability across Oncology R&D, owning the framework, risk registers and BIAs while designing executive-level crisis exercises. Drives emerging-risk assessment, supply-chain nth-tier visibility and the practical use of AI in resilience practice, acting as the audit and regulatory interface for standards such as NIS2.
NIS2 · Business Continuity Software
AstraZeneca · 10000+ people · Public
Leads three mandates for an infectious disease portfolio: defining end-to-end publication strategy from target selection to clinical development, securing grants and partnerships with NGOs and philanthropic funders, and horizon-scanning emerging biotechnology. Partners with discovery, clinical, data and external academic stakeholders, coaching teams and influencing senior decision-makers.
Moderna · 1001–5000 people · Late stage
Lead CMC regulatory strategy for UK-manufactured and UK-licensed mRNA products across development, registration and post-approval lifecycle. Act as primary point of contact with the MHRA, oversee submissions and manufacturing change assessments, and shape global regulatory approaches across cross-functional matrix teams.
MHRA · Generative AI
Fortrea
Owns product strategy, roadmap and innovation for clinical pharmacology clinics and bioanalytical labs, spanning early-phase platforms like ClinSpark, LIMS/LIS, ELN, instrument connectivity and lab automation. Builds business cases and secures funding, governs a regulated portfolio, and leads multidisciplinary product teams and vendors across distributed sites.
ClinSpark · LIMS · LIS +7
Bristol Myers Squibb
Serves as primary medical accountability for Phase 1–3 clinical trials in neuroscience, leading medical monitoring, safety assessment and benefit/risk analysis within a matrixed study delivery team. Partners with clinical scientists on protocol design, site interactions and health authority submissions, and builds relationships with principal investigators and thought leaders.
Moderna · 1001–5000 people · Late stage
Shape global CMC regulatory strategy for an innovative mRNA medicines portfolio, driving international submissions and health authority interactions. Prepare and review CMC sections of regulatory filings, advise Manufacturing and Quality teams, and oversee multiple development programs. An individual contributor role with global reach, working alongside teams using digital and Generative AI tools.
Generative AI
Gilead Sciences
Leads end-to-end Clinical Systems migration initiatives such as CTMS, eTMF and study startup, from strategy and due diligence through implementation, cutover and legacy decommissioning. Oversees data migration programs, CRO integrations and GxP validation, managing vendors, stakeholders and a team of professionals while shaping the Clinical Systems roadmap.
CTMS · eTMF
Parexel
Provides statistical consulting and strategic advice on optimal study designs and analyses across drug, device, and diagnostic clinical development, including preparation for regulatory authority interactions. Serves as a leader in innovative study designs for client accounts and supports new business through proposals, bids, and client presentations, representing clients at key regulatory meetings.
FDA · EMEA · MHRA +2
