Biotechnology Jobs

• Oxford
• On-site
• Senior
• Permanent

Lead the development of a plant cell-based screening platform to evaluate carbon fixation, using quantitative methods and CRISPR-based genome editing in suspension cultures. Apply iterative design-build-test-learn cycles to identify improved photosynthesis enzyme variants and engineered pathways, advancing promising candidates into whole plants. Contribute to IP generation and collaborate across multidisciplinary teams.

CRISPR

• Oxford
• On-site
• Entry level
• Permanent

Design and conduct experiments on nanopore technologies, single-molecule analysis, and 3D tissue engineering, spanning chemistry, biology, physics and engineering. Postdocs lead development of emerging biotech methods, publish impactful research, and mentor junior researchers within a 100+ researcher institute.

3D Printing

• London
• Hybrid
• US$188,100 – US$313,500 pa
• Director
• Permanent

Leads quantitative systems pharmacology and QST modelling within a clinical pharmacology and quantitative medicine group, building mechanistic models of disease and drug action and running simulations to inform trial design. Defines and coordinates MIDD strategies across respiratory, immunology and inflammation programmes, working with biologists, clinicians, pharmacometricians and AI/ML specialists. The role sits in a newly formed centre of excellence and involves representing QSP on internal advisory boards.

• Durham Blackwell Street
• US$188,100 – US$313,500 pa
• Director

Leads quantitative systems pharmacology and QST modelling within a clinical pharmacology and quantitative medicine group, building mechanistic models of disease and drug action and running simulations to assess trial design. Defines and coordinates MIDD strategies across respiratory, immunology and inflammation programmes, working with biologists, clinicians, pharmacometricians and AI/ML specialists. The role sits in a newly established Centre of Excellence for model-informed drug development.

• USA - Pennsylvania - Upper Providence
• Hybrid
• Lead

Lead complex oncology projects, designing and interpreting scientific and clinical strategies while collaborating with cross-functional teams and external partners. Provide expert guidance on scientific, technical and regulatory matters, drive innovation in methodologies, and mentor colleagues. Hybrid role split between London and Upper Providence, Pennsylvania.

• Waltham, United States
• Hybrid · 2 days in office
• US$242,250 – US$403,750 pa
• Director · manages people

Owns the clinical strategy, scientific narrative and benefit-risk framework for a genitourinary oncology asset, acting as the senior clinical voice on the Medicine Development Team core quad. Leads governance and investment discussions, Health Authority interactions and evidence-generation strategy, while directing Senior Scientists who handle study-level delivery. Hybrid role with at least two days per week on-site.

AI-enabled Insights · Data Platforms

• Stevenage
• Hybrid · 2 days in office
• US$242,250 – US$403,750 pa
• Director · manages people

Owns the clinical strategy, scientific narrative and benefit-risk framework for a genitourinary oncology asset, acting as the senior clinical voice on the Medicine Development Team core quad. Leads governance and health authority interactions while directing Senior Scientists who handle study-level delivery, and mentors clinical development talent.

AI

• Zug, Switzerland
• Hybrid · 2 days in office
• US$242,250 – US$403,750 pa
• Director · manages people

Owns the clinical strategy, scientific narrative and benefit-risk framework for a genitourinary oncology asset, acting as the senior clinical authority on the Medicine Development Team core quad. Leads governance and investment discussions, Health Authority interactions and evidence-generation strategy, while mentoring clinical development talent and applying AI-enabled analytics to speed decision-making.

AI · Advanced Analytics

• London
• Hybrid · 2 days in office
• US$242,250 – US$403,750 pa
• Director · manages people

Owns the clinical strategy, scientific narrative and benefit-risk framework for a genitourinary oncology asset, acting as the senior clinical authority within the Medicine Development Team. Leads governance and investment discussions, health authority interactions and evidence-generation strategy, while mentoring clinical development talent and applying AI-enabled analytics to speed decision-making.

AI

• Stevenage
• Hybrid
• £119,250 – £198,750 pa
• Director

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late pre-candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work across small molecules, biologics and antibody drug conjugates, applying AI/ML and quantitative systems pharmacology methods. Presents and defends modelling outcomes to governance boards and regulators, and contributes to protocols, analysis plans and submissions.

NONMEM · R

• USA - Pennsylvania - Upper Providence
• Hybrid · 2 days in office
• US$242,250 – US$403,750 pa
• Director · manages people

Owns the clinical strategy, scientific narrative and benefit-risk framework for genitourinary cancer assets, acting as the senior clinical authority on the Medicine Development Team core quad. Sets asset-level evidence-generation and governance direction while Senior Scientists handle study-level delivery, and represents Clinical Development in health authority and external engagements. Hybrid role with at least two on-site days per week.

AI · Advanced Analytics

• Waltham, United States
• Hybrid
• £188,100 – £313,500 pa
• Director

Leads model-informed drug development for oncology programs, defining and executing model-based strategies from late discovery through lifecycle management. Conducts population PK, exposure-response, simulation-based trial design and dose selection, applying AI/ML, quantitative systems pharmacology and model-based meta-analysis. Presents to governance boards and regulators and works across matrix teams on small molecules, biologics and antibody drug conjugates.

NONMEM · R

• London
• Hybrid
• £119,250 – £198,750 pa
• Director

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work, applying AI/ML and quantitative systems pharmacology methods, and defends results to governance boards and regulators. Sits within Oncology Translational Medicine's Clinical Pharmacology Modelling and Simulation group, working across small molecules, biologics and antibody drug conjugates.

NONMEM · R

• Belgium-Wavre
• Hybrid
• €119,250 – €198,750 pa
• Director

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work, applying AI/ML, quantitative systems pharmacology and model-based meta-analysis to small molecules, biologics and antibody drug conjugates. Presents and defends modelling outcomes to governance boards and regulators, and contributes to protocols, analysis plans and submissions.

NONMEM · R

• USA - Pennsylvania - Upper Providence
• Hybrid
• US$188,100 – US$313,500 pa
• Director

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work across small molecules, biologics and antibody drug conjugates, applying AI/ML and quantitative systems pharmacology methods. Presents and defends modelling outcomes to governance boards and regulators, and contributes to protocols, analysis plans and submissions.

NONMEM · R