Biotechnology Jobs

• Oxford
• Hybrid
• Senior
• Permanent

Develops AI and machine learning systems for synthetic biology, genome design and molecular evolution, with a focus on genome-scale metabolic modelling. Works in a Technology Hub ML engineering team alongside wet-lab scientists, bioinformatics and scientific compute groups, building reproducible training pipelines and MLOps for biological design and discovery.

• Oxford
• On-site
• Lead
• Permanent

Leads vector design strategy for gene edited and transgenic crop programmes, covering expression cassette architecture, guide RNA modules, donor templates and multiplex editing configurations. Owns the design-to-vector-release process, including construct QC, sequence management, vendor workflows and handover packages for transformation teams. Builds an industrial-grade vector design capability for corn, wheat and other strategic species, with SOPs, LIMS/ELN tracking and mentoring of scientists.

ELN · LIMS

• Waltham, United States
• Hybrid
• US$222,750 – US$371,250 pa
• Director

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Coordinates CPMS activities across assets, approves study designs and regulatory documents, and works with cross-functional partners in digital medicine, translational imaging and systems modelling. Based in the newly established Clinical Pharmacology and Quantitative Medicine organisation.

MIDD · QSP · AI/ML

• London
• Hybrid
• US$222,750 – US$371,250 pa
• Director

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Coordinates CPMS activities across assets, approves study designs and regulatory documents, and works with digital medicine, imaging, modelling and data science partners. Reports into the Respiratory, Immunology & Inflammation Research Unit.

AI/ML · Digital Medicine · Translational Imaging +3

• Cambridge
• Director
• Permanent · Flexible

A senior scientific leadership role shaping and delivering a drug discovery strategy, driving adoption of AI-assisted design, predictive modelling, automation and computational science across a diverse portfolio. The post-holder mentors multidisciplinary teams spanning biology, chemistry, protein design, pharmacology and translational sciences, and acts as a scientific ambassador in client engagements, proposals and partnerships.

• Reading
• Remote
• Senior
• Permanent

Supports Pharmacometrics by programming, validating and delivering NONMEM-ready PK/PD datasets from SDTM/ADaM sources using advanced R, covering pre-lock and post-lock clinical data. Includes QC of datasets from external partners and of custom R packages, plus liaison with Data Management, Biostatistics and Bioanalytical teams and regulatory submission deliverables.

R · NONMEM · SDTM +1

• Oxford
• Remote
• £60,000 – £80,000 pa

Serve as the primary scientific resource for customers after instrument installation, guiding onboarding, training and advanced fluorescence imaging workflows. Troubleshoot sample preparation, image acquisition and data analysis issues, build training materials, and feed customer insights to product teams. Remote-based with around 25% travel across the UK and Europe for installations.

• USA - Pennsylvania - Upper Providence
• Hybrid · 2 days in office
• US$189,750 – US$316,250 pa
• Director

Serves as the physician within a clinical program team, leading medical monitoring and safety oversight for genitourinary oncology studies. Interprets clinical and safety data, contributes to protocol development and regulatory interactions, and acts as a core member of the Clinical Matrix Team. May guide other physicians on complex multi-study programs.

AI

• USA - Pennsylvania - Upper Providence
• On-site
• US$222,750 – US$371,250 pa
• Director

Serves as the physician within an oncology clinical programme team, leading medical monitoring and safety oversight for GI cancer studies. Interprets clinical and safety data, contributes to protocol development, and engages investigators, KEEs and health authorities. A core member of the Clinical Matrix Team, providing medical guidance within a matrixed pharma R&D environment.

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