Biotechnology Jobs

GSK · Baar Onyx · US$188,100 – US$313,500 pa

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Sits in the Clinical Pharmacology and Quantitative Medicine organisation, partnering with digital medicine, translational imaging, modelling and biostatistics teams, and drafting regulatory content for FDA, EMA and ICH submissions.

GSK · USA - Pennsylvania - Upper Providence · US$188,100 – US$313,500 pa

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Designs MIDD and ClinPharm evidence strategies, drafts regulatory content for FDA, EMA, CDE, PMDA and ICH, and partners with digital medicine, translational imaging, modelling and data science teams. Sits in the newly formed Clinical Pharmacology and Quantitative Medicine organisation.

GSK · Stevenage · US$242,250 – US$403,750 pa

Leads the global development of a medicine from clinical Proof of Concept to approval in first major markets, acting as single point of accountability. Builds and directs a matrixed Medicine Development Team spanning clinical, medical, commercial and manufacturing, driving strategy, governance and go/no-go decisions. Hybrid role with at least two days on-site per week.

GSK · Stevenage · £119,250 – £198,750 pa

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late pre-candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work across small molecules, biologics and antibody drug conjugates, applying AI/ML and quantitative systems pharmacology methods. Presents and defends modelling outcomes to governance boards and regulators, and contributes to protocols, analysis plans and submissions.

GSK · Stevenage

Leads Quantitative Systems Pharmacology and QST modelling within GSK's Clinical Pharmacology and Quantitative Medicine group, building mechanistic mathematical models of disease, drug action and trial design. Defines clinical pharmacology strategy across the Respiratory, Immunology and Inflammation portfolio, working with biologists, clinicians, statisticians and AI/ML colleagues. The role sits in a newly formed Centre of Excellence for Model-Informed Drug Development, initially in Stevenage with a planned move to Cambridge.

GSK · Grimsby · US$188,100 – US$313,500 pa

Leads quantitative systems pharmacology and QST modelling within a clinical pharmacology and quantitative medicine group, building mechanistic models of disease and drug action and running simulations to inform trial design. Defines and coordinates MIDD strategies across respiratory, immunology and inflammation programmes, working with biologists, clinicians, pharmacometricians and statisticians. Combines inverse-problem modelling, scientific ML and statistical methods to support decisions from exploratory research through clinical development.

GSK · Stevenage

Embedded with chemical manufacturing teams, you build in-silico process models, digital twins and optimization solutions, taking proofs of concept to deployed MVPs at a days-to-weeks cadence. Work is AI-augmented, with coding agents handling routine development while you focus on model identification, scenario planning and handing proven solutions to solutions engineers.

GSK · London

Leads GSK's Forward Deployed Engineering function for CMC R&D, setting strategy, hiring and mentoring engineers, and owning senior BU sponsor relationships. Personally contributes to strategic engagements building digital twins, physical AI and self-driving lab capability, using AI coding agents as the primary development mode.

GSK · London · €81,000 – €135,000 pa

Owns defined planning process areas within GSK's ERP Evolution Programme, ensuring the global S/4 Planning template integrates with OMP, APO and other planning tools across Rx and Vx supply chains. Leads design, configuration input, documentation, testing, data migration and business readiness for UAT, cutover and post-go-live support, working with SAP functional experts, GPO, PLM, Quality and site teams.

GSK · London

Leads a team of risk and compliance business partners supporting GSK's R&D technology, covering clinical, discovery and regulatory systems. Combines hands-on cyber risk consulting and assurance with team leadership, owning the risk register, GxP/SOX compliance, audit readiness and stakeholder engagement across Ware and London sites.

GSK · USA - Pennsylvania - Upper Providence

Individual-contributor alliance lead owning an established central laboratory partnership, balancing strategic direction with hands-on governance. Runs governance forums, monitors KPIs and study delivery, resolves urgent operational issues, and embeds a new operating model, using AI tools to analyse large datasets.

GSK · USA - Pennsylvania - Upper Providence · US$242,250 – US$403,750 pa

Owns the clinical strategy, scientific narrative and benefit-risk framework for genitourinary cancer assets, acting as the senior clinical authority on the Medicine Development Team core quad. Sets asset-level evidence-generation and governance direction while Senior Scientists handle study-level delivery, and represents Clinical Development in health authority and external engagements. Hybrid role with at least two on-site days per week.

GSK · Baar Onyx · US$222,750 – US$371,250 pa

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Coordinates CPMS activities across assets, approves study designs and regulatory documents, and partners with digital medicine, translational imaging and modelling specialists. Reports into the Respiratory, Immunology & Inflammation Research Unit within the new CPQM organisation.

GSK · USA - Pennsylvania - Upper Providence · US$222,750 – US$371,250 pa

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Coordinates CPMS activities across assets, approves study designs and regulatory documents, and partners with digital medicine, translational imaging, biostatistics and AI/ML teams. Sits in the newly formed Clinical Pharmacology and Quantitative Medicine organisation, reporting into the Respiratory, Immunology & Inflammation Research Unit.

GSK · Durham · €87,000 – €145,000 pa

Provides medical and scientific expertise in safety evaluation and risk management for GSK assets across clinical development and post-marketing settings. Leads signal detection, regulatory periodic reports, and benefit-risk assessments while collaborating with cross-functional teams including Clinical Operations, Regulatory, and Biostatistics. Involves presenting complex safety issues to senior governance committees and contributing to global regulatory submissions.