Biotechnology Jobs

• USA - Pennsylvania - Upper Providence
• Hybrid · 2 days in office
• US$284,250 – US$473,750 pa
• Director · manages people

Leads a team of medical directors and clinical scientists designing and executing early-phase oncology trials, including first-in-human and proof-of-concept studies, while bridging preclinical discovery and clinical development. Accountable for clinical development plans, translational and biomarker strategy, and regulatory submissions across lung and head/neck cancer programmes.

AI/ML · Real World Evidence

• USA - Pennsylvania - Upper Providence
• On-site
• US$242,550 – US$404,250 pa
• Director · manages people

Senior physician leader providing medical oversight, safety monitoring and clinical insight across lung cancer studies, from protocol design through data interpretation. Serves on the Clinical Matrix Team, contributes to regulatory interactions and external scientific engagement, and mentors Medical Directors within the programme. Requires deep lung cancer drug development expertise, including early phase trials.

• London
• US$188,100 – US$313,500 pa
• Director

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Sits in the Clinical Pharmacology and Quantitative Medicine organisation, partnering with digital medicine, translational imaging, modelling and data science teams, and drafting regulatory content for FDA, EMA and ICH submissions.

MIDD · QSP · AI/ML

• Stevenage
• US$188,100 – US$313,500 pa
• Director

Lead end-to-end application of Model-Informed Drug Development across the drug development lifecycle, from first-in-human studies through filing and lifecycle management, providing clinical pharmacology strategy and evidence generation. Draft and review regulatory content for FDA, EMA, CDE, PMDA and ICH, and build cross-functional partnerships across digital medicine, translational imaging, AI/ML and biostatistics. The role sits in the newly established Clinical Pharmacology and Quantitative Medicine organisation, reporting into the Respiratory, Immunology & Inflammation Research Unit.

MIDD · QSP · AI/ML

• Durham, United States
• US$188,100 – US$313,500 pa
• Director

Leads end-to-end application of Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Partners with digital medicine, translational imaging, modelling and biostatistics teams, and drafts regulatory content for FDA, EMA, CDE, PMDA and ICH submissions. Based in the newly formed Clinical Pharmacology and Quantitative Medicine organisation, with a strong publication and scientific leadership remit.

MIDD · QSP · AI/ML

• USA - Pennsylvania - Upper Providence
• Hybrid
• US$189,750 – US$316,250 pa
• Director

Leads the design and execution of clinical biomarker and translational medicine strategies for late-stage oncology assets, defining patient segmentation and decision criteria within Clinical Matrix Teams. Validates predictive, pharmacodynamic and resistance biomarkers using platforms such as NGS, ctDNA, flow cytometry and multi-omic analyses to inform dose selection and go/no-go decisions.

IHC/IF · Liquid Biopsy · ctDNA +3

• London
• Hybrid
• US$189,750 – US$316,250 pa
• Director

Leads the design and execution of clinical biomarker and translational medicine strategies for late-stage oncology assets, defining patient segmentation and decision criteria within Clinical Matrix Teams. Oversees biomarker assay development, sample testing plans and data packages across platforms such as NGS, IHC, flow cytometry and ctDNA, working with internal and external partners.

IHC/IF · Liquid Biopsy · ctDNA +3

• Baar Onyx
• US$188,100 – US$313,500 pa
• Director

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Sits in the Clinical Pharmacology and Quantitative Medicine organisation, partnering with digital medicine, translational imaging, modelling and biostatistics teams, and drafting regulatory content for FDA, EMA and ICH submissions.

MIDD · QSP · AI/ML

• USA - Pennsylvania - Upper Providence
• US$188,100 – US$313,500 pa
• Director

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Designs MIDD and ClinPharm evidence strategies, drafts regulatory content for FDA, EMA, CDE, PMDA and ICH, and partners with digital medicine, translational imaging, modelling and data science teams. Sits in the newly formed Clinical Pharmacology and Quantitative Medicine organisation.

MIDD · QSP · AI/ML

• Durham
• Hybrid · 2–3 days in office
• €87,000 – €145,000 pa
• Director

Provides medical and scientific expertise in safety evaluation and risk management for GSK assets across clinical development and post-marketing settings. Leads signal detection, regulatory periodic reports, and benefit-risk assessments while collaborating with cross-functional teams including Clinical Operations, Regulatory, and Biostatistics. Involves presenting complex safety issues to senior governance committees and contributing to global regulatory submissions.

ICH · GVP · CIOMS

• Greater Poland
• Hybrid · 2–3 days in office
• €87,000 – €145,000 pa
• Director
• Permanent

Provides medical and scientific expertise in safety evaluation and risk management for GSK assets across clinical development and post-marketing settings. Leads signal detection, benefit-risk assessment, regulatory periodic reports and RMPs, working within a global cross-functional matrix alongside Clinical Operations, Regulatory and Biostatistics. Distinct for its strong focus on pharmacovigilance governance, safety strategy and scientific writing.

ICH · GVP · CIOMS

• London
• Hybrid · 2–3 days in office
• €87,000 – €145,000 pa
• Director
• Permanent

Provides medical and scientific expertise in safety evaluation and risk management for GSK assets across clinical development and post-marketing settings. Leads signal detection, periodic regulatory reports, RMPs and benefit-risk assessments within a global cross-functional matrix, presenting complex safety issues to senior governance committees. Distinct for its blend of pharmacovigilance strategy, regulatory writing and matrix leadership.

ICH · GVP · CIOMS

• Belgium-Wavre
• Hybrid · 2–3 days in office
• €87,000 – €145,000 pa
• Director
• Permanent

Provides medical and scientific expertise in safety evaluation and risk management for GSK assets across clinical development and post-marketing settings. Leads signal detection, benefit-risk assessment, regulatory periodic reports and RMPs, and contributes to safety strategy within a global cross-functional matrix. Involves presenting complex safety issues to senior governance committees and mentoring matrix colleagues.

ICH · GVP · CIOMS

• Durham, United States
• Lead

Lead authoring and strategic planning for clinical and regulatory documents, including protocols, clinical study reports, briefing documents and submission dossiers. Manages end-to-end writing projects, coordinating contributors, timelines and quality checks, and acts as subject matter expert on medical writing standards, CTD structure and regulatory expectations while driving process improvement and audit readiness.

• London
• Lead

Lead authoring and strategic planning of clinical and regulatory documents such as protocols, clinical study reports, briefing documents and CTD submission dossiers. Manage end-to-end writing projects, coordinating contributors, timelines and quality checks, and act as subject matter expert on medical writing standards and regulatory expectations while driving process improvement and audit readiness.