Biotechnology Jobs

• London
• Hybrid
• Director · manages people

Leads GSK's Forward Deployed Engineering function for CMC R&D, setting strategy, hiring and mentoring engineers, and owning senior BU sponsor relationships. Personally contributes to strategic engagements building digital twins, physical AI and self-driving lab capability, using AI coding agents as the primary development mode.

Claude Code · GitHub Copilot · Databricks AI Assistant +3

• Baar Onyx
• Hybrid
• US$189,750 – US$316,250 pa
• Director

Leads the design and execution of clinical biomarker and translational medicine strategies for late-stage oncology assets, defining patient segmentation and decision criteria within Clinical Matrix Teams. Validates predictive, pharmacodynamic and resistance biomarkers using platforms such as NGS, FISH, PCR, IHC/IF, flow cytometry, liquid biopsy/ctDNA and multi-omic analyses, and oversees sample testing plans and biomarker data packages for clinical and regulatory decisions.

NGS · FISH · PCR +6

• Cambridge, United States
• Hybrid · 3 days in office
• Senior · manages people

Lead in vitro and cellular pharmacology strategy for small-molecule drug design programs, defining screening cascades and guiding biophysical, biochemical and cell-based assays from hit identification to candidate selection. Bridge computational AI/ML predictions with laboratory validation, managing CRO partnerships and collaborating with chemistry, structural biology and translational teams.

SPR · ITC · CRO

• Cambridge, United States
• Hybrid · 3 days in office
• Senior · manages people

Designs and implements translational strategies for small molecule oncology and immunology programs, from early discovery through candidate selection and clinical phase. Oversees CRO activities, PK/PD and safety assessments, and biomarker strategies, bridging computational predictions with laboratory validation. Some roles include managing 2-3 in vivo pharmacologists.

Machine Learning · AlphaFold

• London
• Mid-level
• Permanent

Designs and implements generative models that learn intervention effects from single-cell perturbation and multiomic data, focusing on counterfactual prediction and experimental design. Works in interdisciplinary teams alongside experimental biologists to validate computational hypotheses and guide the highest-signal next experiments, with emphasis on causal coherence and real-world utility over benchmark fit.

• London
• Senior
• Permanent

Develops and benchmarks machine learning models for DNA sequence, regulatory elements and genetic variation, including variant effect prediction and representation learning. Integrates sequence-derived representations with transcriptomic, epigenomic and perturbational data to uncover disease mechanisms and support target prioritisation, working within the interdisciplinary Rosalind team.

Transformer · DNA Language Models · Genomic Foundation Models +2

• Stevenage
• On-site
• US$284,250 – US$473,750 pa
• Director · manages people

Senior physician leader providing medical oversight, safety monitoring and clinical data interpretation across sarcoma oncology studies, from protocol design through regulatory interactions. Serves as a senior member of the Clinical Matrix Team, mentoring Medical Directors and engaging external experts, with a minimum two days a week on-site presence.

Real World Evidence (RWE)

• Zug, Switzerland
• On-site
• US$284,250 – US$473,750 pa
• Director · manages people

Senior physician leader providing medical oversight, safety evaluation and clinical data interpretation across sarcoma oncology studies, from protocol design through regulatory interaction. Serves as a senior member of the Clinical Matrix Team, mentoring Medical Directors and engaging external experts, with a minimum two-day on-site office presence.

Real World Evidence

• Waltham, United States
• US$195,525 – US$325,875 pa
• Director

Senior individual contributor shaping GSK's Enterprise AI opportunity portfolio across market research, competitive intelligence and knowledge graphs, deciding where forward-deployed engineering pods focus. Involves hands-on prototyping with LLMs and agentic systems, building business cases, defining success metrics and running executive conversations to fund and scale AI products.

IQVIA · Komodo · Reltio +5

• USA - Pennsylvania - Upper Providence
• On-site
• US$242,550 – US$404,250 pa
• Director · manages people

Senior physician leader providing medical oversight, safety monitoring and clinical insight across lung cancer studies, from protocol design through data interpretation. Serves on the Clinical Matrix Team, contributes to regulatory interactions and external scientific engagement, and mentors Medical Directors within the programme. Requires deep lung cancer drug development expertise, including early phase trials.

• Upper Providence
• Hybrid · 2 days in office
• US$202,500 – US$371,250 pa
• Director · manages people

Leads clinical development strategy for hepatology assets within the Respiratory, Immunology & Inflammation Research Unit, from target identification through proof-of-concept studies. Accountable for clinical matrix team leadership, protocol design, medical monitoring and safety governance, and regulatory interactions across all development phases.

• USA - Pennsylvania - Upper Providence
• On-site
• US$284,250 – US$473,750 pa
• Director · manages people

Senior physician leader providing medical oversight, safety monitoring and clinical data interpretation across sarcoma oncology studies, from protocol design through regulatory interactions. Serves as a senior member of the Clinical Matrix Team, mentoring Medical Directors and engaging external experts, advisory boards and health authorities.

Real World Evidence (RWE)