Lead and execute model-informed drug development strategies in oncology, applying advanced pharmacometric and AI/ML techniques to optimize clinical trial design, dose selection, and regulatory submissions. Drive innovation in exposure-response analysis, population PK/PD, and quantitative systems pharmacology within a cross-functional R&D environment.
Leads scientific and strategic integration across GSK's hematology oncology portfolio, ensuring cross-program alignment and innovation in clinical development. Provides expert guidance on disease biology, biomarker strategies, and trial design while shaping portfolio-level decision-making. Operates as a senior individual contributor interfacing with clinical teams, external experts, and regulatory bodies.
This role involves managing and monitoring clinical trial sites to ensure compliance with protocols, patient safety, and data quality. The Senior Clinical Research Associate I serves as the primary point of contact for investigator sites, conducts on-site and remote monitoring, resolves protocol issues, and supports enrollment and database release. The position requires extensive knowledge of GCP, regulatory standards, and therapeutic areas such as oncology, with frequent travel expected.
This role involves managing and monitoring clinical trial sites to ensure compliance with Good Clinical Practice, patient safety, and Pfizer's standards. The Clinical Research Associate serves as the primary point of contact for investigator sites, conducts remote and on-site monitoring, supports patient recruitment, and resolves protocol and data issues throughout the trial lifecycle. The position requires close collaboration with study teams and site personnel, with significant travel expected across the UK and internationally.
This role involves designing and implementing end-to-end Variation Planning processes within GSK’s ERP Evolution Programme, focusing on S/4HANA integration across pharmaceutical R&D and supply chain operations. The manager will lead process design, ensure compliance with regulatory and supply chain requirements, and support deployment across global waves, including interim solutions and transition planning. Collaboration with cross-functional teams and governance of change impacts are central to the role.
The role involves designing and implementing Variation Planning processes within GSK’s ERP Evolution Programme using S/4HANA, with a focus on regulatory compliance, supply chain integration, and end-to-end process standardisation across pharmaceutical product lines. The manager will lead process design, testing, and change management across Rx and Vx waves, ensuring alignment with global systems like PLM, Veeva, and RIMS. Collaboration with cross-functional teams is essential to embed robust, scalable solutions and support transition from interim to future-state operations.
Lead clinical pharmacology and modelling & simulation efforts for infectious disease assets, applying pharmacokinetic and pharmacodynamic principles to support drug development from early stages through registration and lifecycle management. Develop population PK/PD and exposure-response models, guide dose selection, and present evidence to regulatory bodies. Work within cross-functional teams while maintaining hands-on involvement in quantitative analysis and strategic decision-making.
This role involves leading oncology clinical development for sarcoma, providing medical oversight across study design, execution, and data interpretation. The Senior Medical Director will guide safety evaluation, contribute to regulatory interactions, and mentor clinical teams, ensuring patient-centred strategies within a global matrix environment. Deep expertise in sarcoma oncology and cross-functional collaboration are central to the position.
Lead clinical pharmacology and modelling & simulation efforts for infectious disease assets, applying pharmacokinetic/pharmacodynamic and exposure-response modelling to inform dose selection, trial design, and regulatory strategy. Work across development phases from early planning to lifecycle management, with a strong emphasis on hands-on quantitative analysis and scientific leadership within a cross-functional environment.
The Variation Planning Process Manager will lead the design and implementation of Variation Planning processes within GSK’s ERP Evolution Programme, focusing on S/4HANA integration across Rx and Vx. The role involves defining end-to-end process frameworks, aligning with cross-functional teams including PLM, Quality, and Regulatory, and ensuring compliance with supply chain and regulatory requirements. Key responsibilities include process documentation, testing, change management, and transition planning from interim to future-state operations.
This role involves leading clinical development in oncology with a focus on sarcoma, providing medical oversight across study design, execution, and data interpretation. The Senior Medical Director will guide safety evaluation, contribute to regulatory interactions, and mentor clinical teams within a matrixed global environment. The position requires deep expertise in oncology drug development and active engagement with external scientific leaders and regulatory authorities.
This role involves leading clinical development for sarcoma within GSK's oncology portfolio, providing medical oversight across study design, execution, and data interpretation. The Senior Medical Director will guide safety monitoring, contribute to regulatory interactions, and represent the programme externally at scientific forums. Based on-site in Waltham, MA, the position requires integration with cross-functional teams and mentorship of clinical staff to ensure patient-centred, scientifically rigorous drug development.
Lead clinical pharmacology, modeling, and simulation efforts for infectious disease assets, driving dose selection and development strategy through population PK/PD and exposure-response modeling. Serve as a scientific leader within cross-functional teams while remaining hands-on with quantitative analyses. Contribute to regulatory submissions and advance model-informed drug development across the R&D lifecycle.
Lead clinical pharmacology and modelling & simulation efforts for infectious disease assets, applying quantitative methods to inform dose selection, trial design, and regulatory strategy. Work across development phases from early planning to lifecycle management, using population PK/PD and exposure-response modelling. Operate as a scientific leader within a cross-functional environment while remaining hands-on with data analysis and model development.
This role involves leading clinical development in oncology with a focus on sarcoma, providing medical oversight and strategic input across study design, execution, and data interpretation. The position ensures patient safety and clinical integrity while guiding cross-functional teams and engaging with external experts. It requires deep expertise in oncology drug development and strong leadership in a matrixed global environment.
