Biotechnology Jobs

• USA - Pennsylvania - Upper Providence
• Hybrid · 2–3 days in office
• US$187,275 – US$312,125 pa
• Director

Leads the scientific design and execution of interventional clinical studies within Medical Affairs, providing medical governance, safety oversight and scientific interpretation of protocols and analysis plans. Collaborates with cross-functional teams, investigators and regulators, and presents results for publications and submissions. Hybrid role with two to three days per week in office.

• USA - Pennsylvania - Upper Providence
• Hybrid
• US$204,000 – US$340,000 pa
• Director

Leads the design and execution of real-world evidence and health outcomes studies across oncology assets, managing timelines, budgets and vendor deliverables. Reviews protocols, analysis plans and publications, and advises medical, market access and commercial teams on payer and HTA evidence needs. Builds relationships with external experts and maintains knowledge of real-world data sources.

• Bath
• Mid-level

Conducts site qualification, initiation, monitoring and close-out visits for a CRO embedded within pharmaceutical sponsor teams, ensuring GCP compliance, patient safety and data integrity. Manages site relationships, recruitment strategies, TMF/ISF documentation and risk escalation, with mentoring of junior staff and up to 40-60% regional travel.

Investigator Site Files · Trial Master Files

• Livingston
• Mid-level

Conducts site qualification, initiation, monitoring and close-out visits for a dedicated clinical trial program, ensuring GCP compliance, patient safety and data integrity. Builds relationships with investigators, resolves data queries, mentors junior staff and travels up to 40-60% within the region.

Investigator Site Files · Trial Master Files

• London
• Hybrid
• PLN 419,250 – PLN 698,750 pa
• Director

Provides medical and scientific leadership in pharmacovigilance and risk management for Respiratory, Inflammation and Immunology assets in clinical development. Interprets safety data, detects and escalates signals, and delivers evidence-based benefit-risk recommendations to senior governance. Works in a global cross-functional matrix, representing Safety on clinical teams and with regulators.

• Warsaw, Poland
• Hybrid
• PLN 419,250 – PLN 698,750 pa
• Director

Provides medical and scientific leadership in pharmacovigilance and risk management for Respiratory, Inflammation and Immunology assets in clinical development. Interprets safety data, detects and escalates signals, and delivers evidence-based benefit-risk recommendations to senior governance. Leads Safety Review Teams and represents Safety on cross-functional clinical matrix teams in a global hybrid environment.

• USA - Pennsylvania - Upper Providence
• Hybrid
• Director

Provides strategic statistical leadership for global medical affairs and market access across GSK's oncology portfolio, designing and analysing non-registrational studies, secondary publications and ISR reviews. Partners with R&D, medical, commercial, RWE and Health Outcomes teams on HTA and payer evidence, applying methods in R, Python or SAS. Hybrid working, based in Stevenage (relocating to Cambridge) or Upper Providence, USA.

R · Python · SAS

• Baar Onyx
• Hybrid
• US$189,750 – US$316,250 pa
• Director

Leads the design and execution of clinical biomarker and translational medicine strategies for late-stage oncology assets, defining patient segmentation and decision criteria within Clinical Matrix Teams. Validates predictive, pharmacodynamic and resistance biomarkers using platforms such as NGS, FISH, PCR, IHC/IF, flow cytometry, liquid biopsy/ctDNA and multi-omic analyses, and oversees sample testing plans and biomarker data packages for clinical and regulatory decisions.

NGS · FISH · PCR +6

• USA - Pennsylvania - Upper Providence
• Hybrid
• US$189,750 – US$316,250 pa
• Director

Leads the design and execution of clinical biomarker and translational medicine strategies for late-stage oncology assets, defining patient segmentation and decision criteria within Clinical Matrix Teams. Validates predictive, pharmacodynamic and resistance biomarkers using platforms such as NGS, ctDNA, flow cytometry and multi-omic analyses to inform dose selection and go/no-go decisions.

IHC/IF · Liquid Biopsy · ctDNA +3

• London
• Hybrid
• US$189,750 – US$316,250 pa
• Director

Leads the design and execution of clinical biomarker and translational medicine strategies for late-stage oncology assets, defining patient segmentation and decision criteria within Clinical Matrix Teams. Oversees biomarker assay development, sample testing plans and data packages across platforms such as NGS, IHC, flow cytometry and ctDNA, working with internal and external partners.

IHC/IF · Liquid Biopsy · ctDNA +3

• Baar Onyx
• Hybrid
• US$222,750 – US$371,250 pa
• Director

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Coordinates CPMS activities across assets, approves study designs and regulatory documents, and partners with digital medicine, translational imaging and modelling specialists. Reports into the Respiratory, Immunology & Inflammation Research Unit within the new CPQM organisation.

MIDD · QSP · AI/ML

• USA - Pennsylvania - Upper Providence
• Hybrid
• US$222,750 – US$371,250 pa
• Director

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Coordinates CPMS activities across assets, approves study designs and regulatory documents, and partners with digital medicine, translational imaging, biostatistics and AI/ML teams. Sits in the newly formed Clinical Pharmacology and Quantitative Medicine organisation, reporting into the Respiratory, Immunology & Inflammation Research Unit.

AI/ML · Digital Medicine · Translational Imaging +2

• Baar Onyx
• US$188,100 – US$313,500 pa
• Director

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Sits in the Clinical Pharmacology and Quantitative Medicine organisation, partnering with digital medicine, translational imaging, modelling and biostatistics teams, and drafting regulatory content for FDA, EMA and ICH submissions.

MIDD · QSP · AI/ML

• USA - Pennsylvania - Upper Providence
• US$188,100 – US$313,500 pa
• Director

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Designs MIDD and ClinPharm evidence strategies, drafts regulatory content for FDA, EMA, CDE, PMDA and ICH, and partners with digital medicine, translational imaging, modelling and data science teams. Sits in the newly formed Clinical Pharmacology and Quantitative Medicine organisation.

MIDD · QSP · AI/ML

• Durham
• Hybrid · 2–3 days in office
• €87,000 – €145,000 pa
• Director

Provides medical and scientific expertise in safety evaluation and risk management for GSK assets across clinical development and post-marketing settings. Leads signal detection, regulatory periodic reports, and benefit-risk assessments while collaborating with cross-functional teams including Clinical Operations, Regulatory, and Biostatistics. Involves presenting complex safety issues to senior governance committees and contributing to global regulatory submissions.

ICH · GVP · CIOMS