Biotechnology Jobs

• USA - Pennsylvania - Upper Providence
• Hybrid
• US$123,000 – US$205,000 pa
• Lead

Owns operational delivery of diagnostics across early and late-stage oncology trials, from biosample collection and clinical trial assays at reference and central labs to analysis-ready, audit-ready data. Works in a matrix with strategy, biomarker, clinical operations, data management, regulatory, quality and procurement teams, plus external CROs, labs and vendors, and mentors colleagues as a subject matter expert.

CRO · Central Labs · Reference Labs

• London
• Director

Provides advanced scientific expertise in safety evaluation and risk management for key oncology assets in clinical development, leading signal detection, benefit-risk assessment and regulatory safety submissions. Represents the Safety Evaluation & Risk Management function on cross-functional clinical matrix and project teams, escalating emerging safety issues to senior governance. Mentors junior staff and partners with Safety Physicians to shape long-term safety strategy.

• New York, United States
• Hybrid · 2–3 days in office
• US$151,800 – US$220,660 pa
• Senior

Integrate phenomics, transcriptomics, genomics and proteomics data to nominate novel targets and validate immunology and inflammation disease biology, piloting new methods for target discovery and early patient population hypotheses. Partner cross-functionally with biologists, chemists, data scientists and engineers to build data packages that drive program milestones and investment decisions.

Python · R · CRISPR

• New York, United States
• Hybrid · 2–3 days in office
• US$151,800 – US$220,660 pa
• Senior

Integrates phenomics, transcriptomics, genomics and proteomics data to nominate and validate oncology targets and define precision oncology patient strategies. Partners cross-functionally with biologists, chemists, engineers and translational experts to build target data packages and pilot novel discovery methods, including agentic target packages and mechanism-of-action work.

CRISPR

• USA - Pennsylvania - Upper Providence
• Hybrid · 2 days in office
• US$242,250 – US$403,750 pa
• Director · manages people

Leads the global development of a medicine from clinical Proof of Concept to approval in first major markets, acting as the single point of accountability. Builds and directs a matrixed Medicine Development Team spanning clinical, medical, commercial and manufacturing, and owns the asset budget and resourcing plan. Hybrid role requiring at least two days per week on-site at a US or UK GSK site.

• Waltham, United States
• Hybrid · 2 days in office
• US$242,250 – US$403,750 pa
• Director · manages people

Leads the global development of a medicine from clinical Proof of Concept through first major-market approval, acting as the single point of accountability. Builds and directs a matrixed Medicine Development Team spanning clinical, medical, commercial and manufacturing, and owns the asset's strategy, budget and governance decisions.

• London
• Hybrid · 2 days in office
• US$242,250 – US$403,750 pa
• Director · manages people

Leads the global development of a medicine from clinical Proof of Concept to approval in first major markets, acting as single point of accountability. Builds and directs a matrixed Medicine Development Team spanning clinical, medical, commercial and manufacturing, driving strategy, governance and go/no-go decisions. Hybrid role with at least two days per week on-site.

• Waltham, United States
• Hybrid
• £188,100 – £313,500 pa
• Director

Leads model-informed drug development for oncology programs, defining and executing model-based strategies from late discovery through lifecycle management. Conducts population PK, exposure-response, simulation-based trial design and dose selection, applying AI/ML, quantitative systems pharmacology and model-based meta-analysis. Presents to governance boards and regulators and works across matrix teams on small molecules, biologics and antibody drug conjugates.

NONMEM · R

• London
• Hybrid
• £119,250 – £198,750 pa
• Director

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work, applying AI/ML and quantitative systems pharmacology methods, and defends results to governance boards and regulators. Sits within Oncology Translational Medicine's Clinical Pharmacology Modelling and Simulation group, working across small molecules, biologics and antibody drug conjugates.

NONMEM · R

• Belgium-Wavre
• Hybrid
• €119,250 – €198,750 pa
• Director

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work, applying AI/ML, quantitative systems pharmacology and model-based meta-analysis to small molecules, biologics and antibody drug conjugates. Presents and defends modelling outcomes to governance boards and regulators, and contributes to protocols, analysis plans and submissions.

NONMEM · R

• USA - Pennsylvania - Upper Providence
• Hybrid
• US$188,100 – US$313,500 pa
• Director

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work across small molecules, biologics and antibody drug conjugates, applying AI/ML and quantitative systems pharmacology methods. Presents and defends modelling outcomes to governance boards and regulators, and contributes to protocols, analysis plans and submissions.

NONMEM · R

• Durham Blackwell Street
• Hybrid
• US$188,100 – US$313,500 pa
• Director

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work, applying AI/ML and quantitative systems pharmacology methods, and defends results to governance boards and regulators. Sits within a matrixed Clinical Pharmacology Modelling and Simulation group working across small molecules, biologics and antibody drug conjugates.

NONMEM · R

• Zug, Switzerland
• Hybrid · 2–3 days in office
• US$222,750 – US$371,250 pa
• Director

Serves as the physician within a clinical programme team, leading medical monitoring, safety oversight and data interpretation for GI oncology studies. Partners with a Senior Scientist and cross-functional matrix teams on protocol development, regulatory interactions and investigator engagement. Requires an on-site presence 2-3 days a week across UK, Swiss or US sites.

AI-enabled Insights

• USA - Pennsylvania - Upper Providence
• Hybrid · 2 days in office
• US$266,250 – US$443,750 pa
• Director · manages people

Strategically leads global development of an oncology medicine from clinical Proof of Concept to approval in first major markets, acting as single point of accountability. Builds and leads a matrixed Medicine Development Team spanning clinical, medical, commercial and manufacturing, driving evidence packages, governance decisions and lifecycle plans.

• Waltham, United States
• Hybrid · 2 days in office
• US$284,250 – US$473,750 pa
• Director · manages people

Leads a team of early clinical development medical directors and clinical scientists, owning Phase I/II clinical development plans including first-in-human, dose-escalation and proof-of-concept studies in lung and head/neck cancers. Bridges preclinical discovery and clinical development, driving translational and biomarker strategy, regulatory submissions and cross-functional matrix teams.

AI/ML