495 jobs for “Clinical Database Programmer - Ecoa”
Provides scientific and medical expertise at study level across early- and late-phase hepatology assets, leading protocol and study document development, serving as medical monitor for Phase 1-4 trials, and interpreting efficacy, safety and biomarker data. Works within cross-functional global study teams and mentors less experienced clinical scientists without formal line management.
Provides scientific and medical expertise at study level across early- and late-phase hepatology assets, leading protocol and study document development, serving as medical monitor for Phase 1–4 trials, and interpreting efficacy, safety and biomarker data. Works within cross-functional global study teams and the Clinical Matrix Team, with informal coaching of less experienced clinical scientists and no formal line management.
Lead all statistical work on assigned neuroscience clinical trials, from protocol development and statistical analysis plans to reporting and exploratory analyses. Drive implementation of innovative trial designs and modern statistical methodologies, collaborating with clinical, regulatory, data management and programming teams to support quantitative decision making.
Lead statistical programming for complex global clinical programs from phase I to IV, coordinating internal and external programmers and setting programming strategy with biostatisticians. Drives adoption of R packages, Shiny applications and AI-enabled tools for visualization and reproducible workflows, while managing resources and acting as functional mentor within the therapy area community.
R · Tidyverse · R Shiny +1
IQVIA
Monitors Phase I-IV clinical trials across UK sites, conducting evaluation, initiation, interim and close-out visits in line with GCP and sponsor requirements. Works closely with the Clinical Trial Manager and Lead CRA, handling source verification, eCRF/EDC data review, query resolution and site training. Requires oncology monitoring experience and involves travel plus mentoring of less experienced CRAs.
EDC · eCRF
IQVIA
Perform complex clinical procedures such as ECG, phlebotomy, spirometry, cannulation and cardiac telemetry on trial volunteers, and collect and report data per protocol. Support Phase I-IV studies at a hospital-based research facility, ensuring compliance with GCP and SOPs while orienting volunteers and assisting nursing colleagues.
Microsoft Word · Microsoft Excel · Microsoft PowerPoint
Isomorphic Labs · 201–500 people · Series A
Lead formulation strategy for small molecules across drug discovery and preclinical development, designing technologies such as solid dispersions and co-crystals to improve solubility, stability and manufacturability. Work within an interdisciplinary team alongside AI/ML drug design platform groups, managing external CRO resources and authoring regulatory submissions.
ASAP
Isomorphic Labs · 201–500 people · Series A
Drive DMPK strategy across drug discovery projects, designing screening cascades and mechanistic experiments while integrating AI/ML and PBPK modelling to predict human dosing, efficacy and safety windows. Work within an interdisciplinary team of drug design and machine learning specialists, authoring regulatory documents and optimising molecule design with chemistry leads.
R · Python · KNIME
Recursion · 501–1000 people · Series C
Integrate phenomics, transcriptomics, genomics and proteomics data to nominate novel targets and validate immunology and inflammation disease biology, piloting new methods for target discovery and early patient population hypotheses. Partner cross-functionally with biologists, chemists, data scientists and engineers to build data packages that drive program milestones and investment decisions.
Python · R · CRISPR
Recursion · 501–1000 people · Series C
Integrates phenomics, transcriptomics, genomics and proteomics data to nominate and validate oncology targets and define precision oncology patient strategies. Partners cross-functionally with biologists, chemists, engineers and translational experts to build target data packages and pilot novel discovery methods, including agentic target packages and mechanism-of-action work.
CRISPR
Ipsen
Leads medical evaluation of external innovation and business development opportunities across Ipsen's oncology portfolio, assessing unmet need, clinical value and target product profiles. Sits on the Global Oncology Medical Leadership team, shaping cross-asset strategy and preparing new products for integration, while engaging external experts and scientific societies.
ESMO · ASCO · AACR
Ipsen
Leads global medical strategy for the Neurosciences portfolio, primarily Dysport Movement Disorders indications, defining evidence generation plans, registries and investigator-sponsored research. Acts as Medical functional lead on the global Asset Team, chairs the Medical & Evidence Generation Team, and represents Ipsen with KOLs, societies and advocacy groups. Also leads, coaches and develops Global Medical Directors across the organisation.
Dysport
Vertex Pharmaceuticals
Lead the DMPK team at Vertex's Oxford site, shaping strategy and operations while sitting on both the Global DMPK and Oxford Site leadership teams. The role directs ADME science across discovery and development programmes, partners with Medicinal Chemistry, Biology, Preclinical Safety and Clinical Pharmacology, and oversees regulatory documentation such as INDs and marketing applications. It combines deep small-molecule DMPK expertise with hiring, mentoring and resource planning.
Labcorp
Trainee role in a purpose-built histology lab, trimming and processing animal tissue samples, performing microtomy, staining and microscopic quality control under Good Laboratory Practice. Full training is provided, with cross-training in necropsy and work in a fast-paced, production-intensive environment.
Automated Tissue Processors · Motorised Microtomes
Imperial College London
Lead the harmonisation, integration and analysis of large-scale multi-omics datasets including single-cell transcriptomics, epigenomics and proteomics, building reproducible Nextflow or Snakemake pipelines on HPC or cloud infrastructure. Work with AI and mathematical modelling teams within a multidisciplinary consortium spanning Imperial, UCL and industry partners on an ARIA-funded programme studying innate immune protection against respiratory viral infections.
Nextflow · Snakemake · Unix +3
