Latest Therapeutics Jobs

Director, Oncology Translational Medicine, Clinical Biomarkers

Leads the design and execution of clinical biomarker and translational medicine strategies for late-stage oncology assets, defining patient segmentation and decision criteria within Clinical Matrix Teams. Oversees biomarker assay development, sample testing plans and data packages across platforms such as NGS, IHC, flow cytometry and ctDNA, working with internal and external partners.

GSK Grimsby US$189,750 – US$316,250 pa

Hybrid

Director, AI/ML MIDD Oncology Clinical Pharmacology, Modeling and Simulation

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late pre-candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work across small molecules, biologics and antibody drug conjugates, applying AI/ML and quantitative systems pharmacology methods. Presents and defends modelling outcomes to governance boards and regulators, and contributes to protocols, analysis plans and submissions.

GSK Stevenage £119,250 – £198,750 pa

Hybrid

Staff Software Engineer (Inference Platform), London

Lead the hardening and scaling of an inference platform serving fleets of cutting-edge ML models for scientific applications. Set strategy and roadmaps, architect next-generation services to solve scaling limits, and partner with research, product and operations teams to align infrastructure with biotech R&D cycles.

Isomorphic Labs London

Hybrid

General Application - Register Your Interest

A general expression-of-interest pipeline for experienced software engineers, ML researchers and engineers, computational chemists and technical program managers. The interdisciplinary team builds predictive and generative AI models for drug design, working across therapeutic areas and modalities. Hybrid working requires three days a week in the London office.

Isomorphic Labs London

Hybrid

Head, Oncology Clinical Development - ADCs

Accountable for end-to-end clinical development strategy for an antibody-drug conjugate asset across multiple tumour types, from first-in-human through registrational trials and launch. Acts as senior clinical representative at governance forums and leads cross-functional, matrixed teams spanning research, precision medicine, medical affairs and commercial.

GSK USA - Pennsylvania - Upper Providence US$242,250 – US$403,750 pa

Hybrid

Medical Director Clinical Development- Respiratory

Provides clinical and scientific leadership across early and late-stage respiratory programs, shaping clinical development plans, study designs and regulatory documents. Leads a cross-functional Clinical Matrix Team, oversees medical monitoring and safety, and partners with biology, regulatory, commercial and biostatistics colleagues. Hybrid working with at least two days per week on-site.

GSK Stevenage US$222,750 – US$371,250 pa

Hybrid

Medical Director, Oncology Clinical Development - Hematology

Serves as the physician on a clinical program team, leading medical monitoring, safety oversight and data interpretation for oncology and hematology studies. Partners with a Senior Scientist and cross-functional groups on protocol development, regulatory interactions and investigator engagement within a matrix team. May guide other physicians on complex multi-study programs.

GSK Waltham, United States US$222,750 – US$371,250 pa

Hybrid

Medical Director, Oncology Clinical Development - Hematology

Serves as the physician on a clinical program team, leading medical monitoring and safety oversight for oncology and hematology studies. Interprets clinical and safety data, contributes to protocol development and regulatory interactions, and acts as a core member of the Clinical Matrix Team. May mentor other physicians on complex multi-study programs.

GSK Stevenage

Hybrid

Medical Director, Oncology Clinical Development - Hematology

Serves as the physician on a clinical program team, leading medical monitoring and safety oversight for oncology and hematology studies. Interprets clinical and safety data, contributes to protocol development, and engages investigators, regulators and cross-functional matrix teams. May guide other physicians on complex multi-study programs.

GSK London

Hybrid

Medical Director, Oncology Clinical Development - Hematology

Serves as the physician on a clinical program team, leading medical monitoring and safety oversight for oncology and hematology studies. Interprets clinical and safety data, contributes to protocol development, and engages with investigators, regulators, and cross-functional matrix teams. May guide other physicians on complex multi-study programs.

GSK Mississauga, Canada US$222,750 – US$371,250 pa

Hybrid

Medical Director Clinical Development- Respiratory

Provides clinical and scientific leadership across early and late-stage respiratory development programmes, shaping clinical development plans, study designs and regulatory documents. Leads a cross-functional Clinical Matrix Team, oversees medical monitoring and safety governance, and partners with biology, translational sciences, regulatory and commercial colleagues. Distinct for its focus on pulmonary hypertension and translational biomarker work within GSK's Respiratory, Immunology & Inflammation Research Unit.

GSK London US$222,750 – US$371,250 pa

Hybrid

Medical Director Clinical Development- Respiratory

Provides clinical and scientific leadership across respiratory and immunology clinical development programmes, shaping clinical development plans, study designs and regulatory documents. Leads a cross-functional Clinical Matrix Team, oversees medical monitoring and safety governance, and acts as the clinical point of contact for regulators, investigators and key external experts. Hybrid working with at least two days per week on-site.

GSK Waltham, United States US$222,750 – US$371,250 pa

Hybrid

Medical Director Clinical Development- Respiratory

Provides clinical and scientific leadership across early and late-stage respiratory programmes, shaping clinical development plans, study designs and regulatory documents. Leads a cross-functional Clinical Matrix Team, oversees medical monitoring and safety governance, and partners with biology, regulatory, commercial and statistics groups to advance differentiated medicines.

GSK Stevenage US$222,750 – US$371,250 pa

Hybrid

Medical Director, Oncology Clinical Development - Hematology

Serves as the physician within oncology clinical program teams, leading medical monitoring, safety oversight, and clinical data interpretation across studies. Partners with Senior Scientists and cross-functional matrix teams on protocol development, regulatory interactions, and investigator engagement. May guide other physicians on complex multi-study programs within the clinical strategy set by the Clinical Development Lead.

GSK USA - Pennsylvania - Upper Providence US$222,750 – US$371,250 pa

Hybrid

Medical Director, Oncology Clinical Development - Hematology

Serves as the physician within oncology clinical program teams, leading medical monitoring, safety oversight and clinical data interpretation for hematology studies. Partners with a Senior Scientist and cross-functional matrix teams on protocol development, regulatory interactions and investigator engagement, with hybrid working at least two days on-site.

GSK Baar Onyx US$222,750 – US$371,250 pa

Hybrid