Latest Drug Discovery Jobs

Medical Director, Clinical Development (Oncology), Cambridge, MA

This role involves leading the clinical development of oncology drug candidates derived from AI-driven insights, translating them into actionable trial strategies, and ensuring scientific and regulatory rigor. The Medical Director will act as the primary medical monitor, guide cross-functional teams, and represent the company in interactions with regulators and key opinion leaders. The position emphasizes patient safety, protocol compliance, and strategic input from discovery through clinical proof-of-concept.

Isomorphic Labs Cambridge, United Kingdom

Hybrid Permanent

CMC Project Lead (Next Generation Biologics and ADCs), London

Lead the CMC strategy for next-generation biologics and Antibody-Drug Conjugates (ADCs), driving end-to-end technical development from AI-designed candidates to clinical manufacturing. Orchestrate complex processes including cell line development, conjugation chemistry, analytical characterization, and regulatory filings, while managing global CDMO partnerships and ensuring compliance with cGMP and global regulatory standards.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Research Scientist, Immunology

This role involves designing and executing complex in vitro assays using primary human immune cells and patient-derived tissues to support drug discovery in immunology. The scientist will contribute to target validation, mechanism of action studies, and small molecule screening, leveraging advanced technologies like flow cytometry and high-content imaging. Working within cross-functional teams, they will integrate immunology expertise into both in vitro and in vivo workstreams across the therapeutic pipeline.

Recursion Crathes, Alba / Scotland, United Kingdom £52,000 – £70,400 pa

On-site Permanent

Research Synthesis Chemist

Your work will change lives. Including your own.The Impact You’ll MakeWe are growing our chemistry team at Recursion and are seeking a Research Synthetic Chemist to join our Automated Chemistry group. We are looking for an individual that thrives in...

Recursion Crathes, Alba / Scotland, United Kingdom

AI Strategy Director, Development Operations

The AI Strategy Director role involves driving the AI-native Development Operations strategy at GSK, focusing on identifying and deploying AI solutions that accelerate clinical trials and improve patient outcomes. Responsibilities include prioritizing AI opportunities, evaluating external capabilities, and leading cross-functional teams to prototype and deploy AI-enabled workflows.

GSK Stevenage, United Kingdom

On-site Permanent

Manager, Translational Biomarker Data Pathways & Re-use

This role involves leading the setup, stabilization, and scaling of end-to-end translational data pathways, ensuring biomarker datasets are reusable and accessible. Key responsibilities include resolving systemic barriers, aligning data delivery with decision timelines, and developing repeatable processes for data re-use across multiple functions.

GSK Stevenage, United Kingdom

Hybrid Permanent

Director, HTA, Value & Evidence (HV&E), PCOA

Develops and executes patient-centered outcomes assessment (PCOA) strategies in clinical and observational studies to support regulatory approval, market access, and reimbursement of Pfizer’s innovative therapies. Acts as a subject matter expert, collaborating with cross-functional teams and external stakeholders to ensure patient experience data are integrated as scientific evidence. Leads research, manages consultants, and ensures alignment with evolving regulatory and HTA standards.

Pfizer US$176,600 – US$294,300 pa

Hybrid Permanent

Director, HTA, Value & Evidence (HV&E), PCOA

Develops and executes patient-centered outcomes assessment strategies to support clinical development, regulatory approval, and market access for Pfizer’s innovative therapies. Leads evidence generation using clinical outcome assessments and collaborates across R&D, regulatory, and commercial teams to ensure patient experience data informs decision-making. Provides technical leadership in COA methodology, regulatory dossiers, and global evidence planning.

Pfizer US$176,600 – US$294,300 pa

Hybrid Permanent

Executive Director, Strategy, Oncology R&D

This role involves owning and driving the global Oncology R&D strategy, setting priorities for the senior executive team, and transforming the approach to deliver impact for patients. The Executive Director will lead the creation of comprehensive therapeutic area strategies, provide strategic recommendations to senior leadership, and collaborate across functions to drive innovation and impact.

AstraZeneca Cambridge, United Kingdom

On-site Permanent

Executive Director, Strategy, Oncology R&D

This role involves crafting and driving the global Oncology R&D strategy, integrating clinical, scientific, and commercial insights to shape portfolio priorities. You will advise senior leadership, optimize investment decisions, and collaborate across functions to deliver high-impact strategic outcomes.

AstraZeneca United States US$270,222 – US$405,332 pa

On-site Permanent

Senior Data Strategy & Analytics Specialist

This role involves designing and executing data strategies that integrate clinical, operational, and real-world data to support drug development. The specialist will act as a subject matter expert in data curation and analytics, working closely with scientific teams to improve data accessibility and usability. The position emphasizes the application of FAIR data principles and production-grade analytical workflows within a regulated environment.

Roche Welwyn Hatfield, United Kingdom

Hybrid Permanent

Principal Scientist, Immunogenicity and Ligand Binding Assays

This role involves leading scientific strategy and execution for immunogenicity and ligand binding assays in support of Moderna’s mRNA-LNP therapeutic programs. The Principal Scientist will oversee regulated bioanalytical activities including assay development, validation, and sample analysis, ensuring compliance with GcLP, GLP, and regulatory standards. The position emphasizes data integrity, cross-functional collaboration, and integration of emerging technologies, including AI-enabled data analysis, to accelerate clinical development.

Moderna Oxford, United Kingdom

Hybrid Permanent

Senior Group Director, Safety Development & Processes

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive...

Roche Welwyn Hatfield, United Kingdom

Senior Project Specialist, Clinical Supplies

This role involves managing end-to-end clinical supply operations for Moderna’s mRNA-based therapies, ensuring investigational products are labeled, packaged, and distributed efficiently and in compliance with regulatory standards. The specialist coordinates with CROs, vendors, and internal teams to maintain supply chain continuity, troubleshoot logistics, and support digital innovation in supply systems, including AI-enabled tools and IRT platforms.

Moderna

Hybrid Permanent

Global Program Safety Team Lead - Neuroscience

This role involves leading medical safety strategy for neuroscience drug development programs at Novartis, managing global cross-functional teams, and ensuring robust benefit-risk evaluation throughout the product lifecycle. The position requires deep expertise in safety signal detection, regulatory submissions, and mentoring safety professionals, with a strong focus on clinical development and lifecycle management. Based in London or remotely, the role plays a key part in shaping global safety standards and driving patient-centric innovation.

Novartis London, United Kingdom £104,790 – £194,610 pa

Hybrid Permanent