Biotechnology Jobs

• Waltham, United States
• Hybrid
• £188,100 – £313,500 pa
• Director

Leads model-informed drug development for oncology programs, defining and executing model-based strategies from late discovery through lifecycle management. Conducts population PK, exposure-response, simulation-based trial design and dose selection, applying AI/ML, quantitative systems pharmacology and model-based meta-analysis. Presents to governance boards and regulators and works across matrix teams on small molecules, biologics and antibody drug conjugates.

NONMEM · R

• London
• Hybrid
• £119,250 – £198,750 pa
• Director

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work, applying AI/ML and quantitative systems pharmacology methods, and defends results to governance boards and regulators. Sits within Oncology Translational Medicine's Clinical Pharmacology Modelling and Simulation group, working across small molecules, biologics and antibody drug conjugates.

NONMEM · R

• Mississauga, Canada
• Hybrid · 2 days in office
• US$222,750 – US$371,250 pa
• Director

Serves as the physician on a clinical program team, leading medical monitoring and safety oversight for oncology and hematology studies. Interprets clinical and safety data, contributes to protocol development, and engages with investigators, regulators, and cross-functional matrix teams. May guide other physicians on complex multi-study programs.

AI

• London
• Hybrid · 2 days in office
• US$222,750 – US$371,250 pa
• Director

Provides clinical and scientific leadership across early and late-stage respiratory development programmes, shaping clinical development plans, study designs and regulatory documents. Leads a cross-functional Clinical Matrix Team, oversees medical monitoring and safety governance, and partners with biology, translational sciences, regulatory and commercial colleagues. Distinct for its focus on pulmonary hypertension and translational biomarker work within GSK's Respiratory, Immunology & Inflammation Research Unit.

• Waltham, United States
• Hybrid · 2 days in office
• US$222,750 – US$371,250 pa
• Director

Provides clinical and scientific leadership across respiratory and immunology clinical development programmes, shaping clinical development plans, study designs and regulatory documents. Leads a cross-functional Clinical Matrix Team, oversees medical monitoring and safety governance, and acts as the clinical point of contact for regulators, investigators and key external experts. Hybrid working with at least two days per week on-site.

• Stevenage
• Hybrid · 2 days in office
• US$222,750 – US$371,250 pa
• Director

Provides clinical and scientific leadership across early and late-stage respiratory programmes, shaping clinical development plans, study designs and regulatory documents. Leads a cross-functional Clinical Matrix Team, oversees medical monitoring and safety governance, and partners with biology, regulatory, commercial and statistics groups to advance differentiated medicines.

• USA - Pennsylvania - Upper Providence
• Hybrid · 2 days in office
• US$222,750 – US$371,250 pa
• Director

Serves as the physician within oncology clinical program teams, leading medical monitoring, safety oversight, and clinical data interpretation across studies. Partners with Senior Scientists and cross-functional matrix teams on protocol development, regulatory interactions, and investigator engagement. May guide other physicians on complex multi-study programs within the clinical strategy set by the Clinical Development Lead.

AI

• Baar Onyx
• Hybrid · 2 days in office
• US$222,750 – US$371,250 pa
• Director

Serves as the physician within oncology clinical program teams, leading medical monitoring, safety oversight and clinical data interpretation for hematology studies. Partners with a Senior Scientist and cross-functional matrix teams on protocol development, regulatory interactions and investigator engagement, with hybrid working at least two days on-site.

AI

• USA - Pennsylvania - Upper Providence
• Hybrid · 2 days in office
• US$222,750 – US$371,250 pa
• Director

Provides clinical and scientific leadership across early and late-stage respiratory programs, designing clinical development plans, protocols and regulatory documents while overseeing medical monitoring and participant safety. Leads a cross-functional Clinical Matrix Team, shaping translational strategy, target validation and evidence generation in partnership with biology, regulatory and commercial groups.

• London
• Director

Provides advanced scientific expertise in safety evaluation and risk management for key oncology assets in clinical development, leading signal detection, benefit-risk assessment and regulatory safety submissions. Represents the Safety Evaluation & Risk Management function on cross-functional clinical matrix and project teams, escalating emerging safety issues to senior governance. Mentors junior staff and partners with Safety Physicians to shape long-term safety strategy.

• Poznan Grunwaldzka
• PLN 525,750 – PLN 876,250 pa
• Director

Provides advanced scientific expertise in safety evaluation and risk management for key oncology assets in clinical development, leading signal detection, benefit-risk assessment and regulatory safety submissions. Represents SERM on cross-functional clinical matrix teams, escalates emerging safety issues to governance bodies and mentors junior staff within a global matrix environment.

• Belgium-Wavre
• €141,000 – €235,000 pa
• Director

Provides advanced scientific expertise in safety evaluation and risk management for key oncology assets in clinical development, leading signal detection, benefit-risk assessment and regulatory safety submissions. Represents SERM on cross-functional clinical matrix teams, escalates emerging safety issues to governance bodies and mentors junior staff within a global matrix.

• Siena, Italy
• €124,500 – €207,500 pa
• Director

Provides advanced scientific expertise in safety evaluation and risk management for key oncology assets in clinical development, leading signal detection, benefit-risk assessment and regulatory safety submissions. Represents SERM on cross-functional clinical matrix teams, escalates emerging safety issues to governance bodies and mentors junior staff within a global matrix environment.

• Waltham, United States
• Hybrid · 2 days in office
• US$242,250 – US$403,750 pa
• Director · manages people

Owns the clinical strategy, scientific narrative and benefit-risk framework for a genitourinary oncology asset, acting as the senior clinical voice on the Medicine Development Team core quad. Leads governance and investment discussions, Health Authority interactions and evidence-generation strategy, while directing Senior Scientists who handle study-level delivery. Hybrid role with at least two days per week on-site.

AI-enabled Insights · Data Platforms

• Stevenage
• Hybrid · 2 days in office
• US$242,250 – US$403,750 pa
• Director · manages people

Owns the clinical strategy, scientific narrative and benefit-risk framework for a genitourinary oncology asset, acting as the senior clinical voice on the Medicine Development Team core quad. Leads governance and health authority interactions while directing Senior Scientists who handle study-level delivery, and mentors clinical development talent.

AI