Biotechnology Jobs

• London
• On-site
• US$284,250 – US$473,750 pa
• Director · manages people

Senior physician leader providing medical oversight, safety evaluation and clinical data interpretation across sarcoma oncology studies, from protocol design through regulatory interactions. Serves on the Clinical Matrix Team, mentors Medical Directors and engages external experts, with a minimum two days a week on-site presence.

Real World Evidence

• Waltham, United States
• On-site
• US$284,250 – US$473,750 pa
• Director · manages people

Senior physician leader providing medical oversight, safety evaluation and clinical data interpretation across sarcoma oncology studies, from protocol design through regulatory interactions. Sits on the Clinical Matrix Team, mentors Medical Directors and engages external experts, KEEs and advisory boards. Requires deep soft tissue sarcoma and osteosarcoma drug development expertise.

GCP · ICH Guidelines · Real World Evidence

• London
• Hybrid
• Director

Lead CMC regulatory strategy for UK-manufactured and UK-licensed mRNA products across development, registration and post-approval lifecycle. Act as primary point of contact with the MHRA, oversee submissions and manufacturing change assessments, and shape global regulatory approaches across cross-functional matrix teams.

MHRA · Generative AI

• Oxford
• On-site
• Mid-level

Performs routine environmental monitoring and critical utility sampling, plus water testing for TOC, conductivity, bioburden and endotoxin in a GMP manufacturing facility. Executes QC microbiology methods including sterility, bioburden and endotoxin testing, supports method transfers and qualifications, and authors quality records such as deviations and CAPAs. Site-based role working closely with AS&T groups and contract labs on mRNA products.

Vitek · Isolator Technology · LIMS

• Stevenage
• Hybrid · 2 days in office
• US$222,750 – US$371,250 pa
• Director

Provides clinical and scientific leadership across early and late-stage respiratory programmes, shaping clinical development plans, study designs and regulatory documents. Leads a cross-functional Clinical Matrix Team, oversees medical monitoring and safety governance, and partners with biology, regulatory, commercial and statistics groups to advance differentiated medicines.

• USA - Pennsylvania - Upper Providence
• Hybrid · 2 days in office
• US$222,750 – US$371,250 pa
• Director

Provides clinical and scientific leadership across early and late-stage respiratory programs, designing clinical development plans, protocols and regulatory documents while overseeing medical monitoring and participant safety. Leads a cross-functional Clinical Matrix Team, shaping translational strategy, target validation and evidence generation in partnership with biology, regulatory and commercial groups.

• Waltham, United States
• Hybrid
• US$222,750 – US$371,250 pa
• Director

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Coordinates CPMS activities across assets, approves study designs and regulatory documents, and works with cross-functional partners in digital medicine, translational imaging and systems modelling. Based in the newly established Clinical Pharmacology and Quantitative Medicine organisation.

MIDD · QSP · AI/ML

• London
• Hybrid
• US$222,750 – US$371,250 pa
• Director

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Coordinates CPMS activities across assets, approves study designs and regulatory documents, and works with digital medicine, imaging, modelling and data science partners. Reports into the Respiratory, Immunology & Inflammation Research Unit.

AI/ML · Digital Medicine · Translational Imaging +3

• Stevenage
• Hybrid
• US$222,750 – US$371,250 pa
• Director

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Coordinates CPMS activities across assets, approves study designs and regulatory documents, and works with digital medicine, translational imaging and modelling specialists. Based in Stevenage with a planned relocation to Cambridge, UK by early 2029.

MIDD · QSP · AI/ML

• Durham, United States
• Hybrid
• US$222,750 – US$371,250 pa
• Director

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Coordinates CPMS activities across assets, approves study designs and regulatory documents, and partners with digital medicine, translational imaging, biostatistics and AI/ML teams. Reports into the Respiratory, Immunology & Inflammation Research Unit within the new Clinical Pharmacology and Quantitative Medicine organisation.

MIDD · QSP · AI/ML

• Waltham, United States
• US$188,100 – US$313,500 pa
• Director

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Drafts regulatory content for FDA, EMA, CDE, PMDA and ICH submissions, and partners with digital medicine, translational imaging, modelling and data science teams to embed quantitative approaches into asset-level decisions.

MIDD · QSP · AI/ML

• London
• US$188,100 – US$313,500 pa
• Director

Leads end-to-end Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Sits in the Clinical Pharmacology and Quantitative Medicine organisation, partnering with digital medicine, translational imaging, modelling and data science teams, and drafting regulatory content for FDA, EMA and ICH submissions.

MIDD · QSP · AI/ML

• Stevenage
• US$188,100 – US$313,500 pa
• Director

Lead end-to-end application of Model-Informed Drug Development across the drug development lifecycle, from first-in-human studies through filing and lifecycle management, providing clinical pharmacology strategy and evidence generation. Draft and review regulatory content for FDA, EMA, CDE, PMDA and ICH, and build cross-functional partnerships across digital medicine, translational imaging, AI/ML and biostatistics. The role sits in the newly established Clinical Pharmacology and Quantitative Medicine organisation, reporting into the Respiratory, Immunology & Inflammation Research Unit.

MIDD · QSP · AI/ML

• Durham, United States
• US$188,100 – US$313,500 pa
• Director

Leads end-to-end application of Model-Informed Drug Development and clinical pharmacology strategy across the drug development lifecycle, from first-in-human studies through filing and lifecycle management. Partners with digital medicine, translational imaging, modelling and biostatistics teams, and drafts regulatory content for FDA, EMA, CDE, PMDA and ICH submissions. Based in the newly formed Clinical Pharmacology and Quantitative Medicine organisation, with a strong publication and scientific leadership remit.

MIDD · QSP · AI/ML

• Stevenage
• Director

Leads Quantitative Systems Pharmacology and QST modelling within GSK's Clinical Pharmacology and Quantitative Medicine group, building mechanistic mathematical models of disease, drug action and trial design. Defines clinical pharmacology strategy across the Respiratory, Immunology and Inflammation portfolio, working with biologists, clinicians, statisticians and AI/ML colleagues. The role sits in a newly formed Centre of Excellence for Model-Informed Drug Development, initially in Stevenage with a planned move to Cambridge.