Latest Genetic Engineering Jobs

Director, AI/ML MIDD Oncology Clinical Pharmacology, Modeling and Simulation

Leads model-informed drug development for oncology programs, defining and executing model-based strategies from late discovery through lifecycle management. Conducts population PK, exposure-response, simulation-based trial design and dose selection, applying AI/ML, quantitative systems pharmacology and model-based meta-analysis. Presents to governance boards and regulators and works across matrix teams on small molecules, biologics and antibody drug conjugates.

GSK Waltham, United States £188,100 – £313,500 pa

Hybrid

Director, AI/ML MIDD Oncology Clinical Pharmacology, Modeling and Simulation

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work, applying AI/ML and quantitative systems pharmacology methods, and defends results to governance boards and regulators. Sits within Oncology Translational Medicine's Clinical Pharmacology Modelling and Simulation group, working across small molecules, biologics and antibody drug conjugates.

GSK London £119,250 – £198,750 pa

Hybrid

(Fixed-Term) Manufacturing Associate

Hands-on individual contributor operating production equipment for mRNA vaccine manufacturing under cGMP, following SOPs and safety requirements. Involves troubleshooting equipment and digital issues, basic maintenance, documentation with Quality Assurance, and RCA/CAPA investigations. Based fully onsite at Harwell, with exposure to continuous improvement and emerging digital and Generative AI tools.

Moderna Drug Manufacturing

On-site Temporary Clearance Required

(Fixed Term) Scientist, Immunogenicity, Bioanalytical and Molecular Assays

Designs and delivers immunogenicity and bioanalytical strategies for regulated clinical programmes, developing ADA, nAb, PK and PD assays using ELISA, MSD and cell culture. Works with multidisciplinary teams to validate assays, manage reagents and SOPs, and integrate digital and AI-enabled tools. Site-based at Harwell within a growing mRNA-focused team.

Moderna Oxford

On-site Contract Clearance Required

Structural Biology & Biophysics - Industrial Placement (12 Months)

A 12-month laboratory-based industrial placement within the Structural Biology & Biophysics department, working at the interface with Biology on a collaborative project. The role involves membrane protein preparation and reconstitution into lipid-based model systems, functional characterisation using electrophysiology, and interpreting biochemical and biophysical data to support early drug discovery.

Vertex Pharmaceuticals Oxford

Hybrid Internship

Executive Medical Director, Clinical Development Lead - Oncology GU

Enterprise-level clinical strategy leader for a genitourinary oncology asset, owning the clinical roadmap, benefit-risk framework and governance/investment decisions across the lifecycle. Sits on the Medicine Development Team core quad, represents Clinical Development in Health Authority interactions and external engagements, and directs Senior Scientists who handle study-level delivery. Distinct for its asset-level strategic accountability and emphasis on AI-enabled insights and advanced analytics.

GSK Grimsby US$284,250 – US$473,750 pa

Hybrid

Clinical Development Medical Director- Hepatology

Leads clinical development strategy for hepatology assets within the Respiratory, Immunology & Inflammation Research Unit, overseeing study design, medical monitoring, and regulatory interactions. Accountable for the Clinical Matrix Team, target validation, translational plans, and Go/No Go decision criteria across early-phase programs. Hybrid role requiring on-site presence at least two days per week.

GSK Boston, United States US$222,750 – US$371,250 pa

Hybrid

Clinical Development Medical Director- Hepatology

Leads clinical development strategy for hepatology assets within the Respiratory, Immunology & Inflammation Research Unit, identifying next-generation liver disease targets and progressing them to proof-of-concept. Accountable for clinical development plans, study protocols, medical monitoring and safety governance, and chairs the Clinical Matrix Team. Hybrid role with at least two days per week on-site.

GSK Stevenage US$202,500 – US$371,250 pa

Hybrid

Executive Medical Director, Clinical Development Lead - Oncology GU

Owns the clinical strategy, scientific narrative and benefit-risk framework for a genitourinary oncology asset, acting as the senior clinical authority on the Medicine Development Team core quad. Sets asset-level evidence generation and governance direction while study-level delivery is led by Senior Scientists, and represents Clinical Development in Health Authority interactions, advisory boards and alliance partnerships. Uses AI-enabled insights and advanced analytics to sharpen development decisions and mentors clinical development talent.

GSK Stevenage

Hybrid

Medical Director, Oncology Clinical Development - GU

Serves as the physician within an oncology clinical program team, leading medical monitoring and safety oversight for genitourinary cancer studies. Interprets clinical and safety data, contributes to protocol development and regulatory interactions, and acts as a core member of the Clinical Matrix Team. Hybrid role requiring on-site presence at least two days per week.

GSK Zug, Switzerland US$189,750 – US$316,250 pa

Hybrid

Medical Director, Oncology Clinical Development - GU

Serves as the physician within a clinical program team, leading medical monitoring and safety oversight for genitourinary oncology studies. Interprets clinical and safety data, contributes to protocol development and regulatory interactions, and acts as a core member of the Clinical Matrix Team. Hybrid role requiring on-site presence at least two days per week.

GSK Waltham, United States US$189,750 – US$316,250 pa

Hybrid

Medical Director Clinical Development- Aging

Provides clinical and scientific leadership across early-phase clinical development programs in GSK's Respiratory, Immunology & Inflammation Research Unit, focusing on aging. Leads the Clinical Matrix Team, designs clinical development plans and study protocols, oversees medical monitoring and safety, and represents programs in regulatory interactions. Works cross-functionally with biology, translational sciences, commercial, and regulatory partners.

GSK Waltham, United States US$189,750 – US$316,250 pa

Hybrid

Medical Director, Oncology Clinical Development - GU

Serves as the physician within a clinical program team, leading medical monitoring and safety oversight for genitourinary oncology studies. Interprets clinical and safety data, contributes to protocol development and regulatory interactions, and acts as a core member of the Clinical Matrix Team. Hybrid role with at least two days per week on-site.

GSK Stevenage

Hybrid

Medical Director Clinical Development- Aging

Provides clinical and scientific leadership across translational and clinical studies within GSK's Respiratory, Immunology & Inflammation Research Unit, with a focus on aging. Leads a Clinical Matrix Team, designs clinical development plans and protocols, and oversees medical monitoring, safety and regulatory interactions. Hybrid working with at least two days per week on-site, initially in Stevenage before a planned relocation to Cambridge, UK.

GSK Stevenage US$189,750 – US$316,250 pa

Hybrid

Medical Director, Oncology Clinical Development - GU

Serves as the physician within oncology clinical program teams, leading medical monitoring, safety oversight and clinical data interpretation for genitourinary cancer studies. Partners with the Senior Scientist and cross-functional Clinical Matrix Team on protocol development, investigator engagement and regulatory interactions, with hybrid working of at least two days on-site per week.

GSK London

Hybrid