Biotechnology Jobs

493 jobs for “Clinical Data Manager - Early Phase”

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GSK logo

GSK · 10000+ people · Public

VP, Medicine Development Leader- Cancer Vaccines, Oncology Research Unit

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  • Zug, Switzerland
  • Hybrid · 2 days in office
  • US$340,500 – US$567,500 pa
  • Director · manages people

Leads global development of a cancer vaccine asset from late-stage transition through approval and launch, acting as single point of accountability across major markets. Builds and directs a matrix Medicine Development Team spanning clinical development, immunology/biomarkers, manufacturing, regulatory, safety, medical affairs and commercial, and serves as asset spokesperson to senior governance boards.

mRNA · Checkpoint Inhibitors

2 weeks ago
GSK logo

GSK · 10000+ people · Public

VP, Medicine Development Leader- Cancer Vaccines, Oncology Research Unit

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  • Upper Providence
  • Hybrid · 2 days in office
  • US$340,500 – US$567,500 pa
  • Director · manages people

Leads global development of a cancer vaccine asset from late-stage transition through approval and launch, acting as single point of accountability. Builds and leads a matrix Medicine Development Team spanning clinical development, immunology, manufacturing, regulatory, safety, medical affairs and commercial, and drives strategy, go/no-go decisions and lifecycle planning.

mRNA · Checkpoint Inhibitors

2 weeks ago

IQVIA

Research Nurse

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  • Manchester
  • On-site
  • Entry level

Perform complex clinical procedures such as ECG, phlebotomy, spirometry, cannulation and cardiac telemetry on trial volunteers, and collect and report data per protocol. Support Phase I-IV studies at a hospital-based research facility, ensuring compliance with GCP and SOPs while orienting volunteers and assisting nursing colleagues.

Microsoft Word · Microsoft Excel · Microsoft PowerPoint

2 weeks ago

IQVIA

PK/PD Statistical Programmer (m/w/d) - homebased

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  • Reading
  • Remote
  • Senior
  • Permanent

Supports Pharmacometrics by programming, validating and delivering NONMEM-ready PK/PD datasets from SDTM/ADaM sources using advanced R, covering pre-lock and post-lock clinical data. Includes QC of datasets from external partners and of custom R packages, plus liaison with Data Management, Biostatistics and Bioanalytical teams and regulatory submission deliverables.

R · NONMEM · SDTM +1

Last month
Novartis logo

Novartis

Regulatory Writer

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  • Home Worker
  • Remote
  • £49,140 – £91,260 pa

Author and manage high-quality regulatory documents for medicines, working with cross-functional clinical and submission teams. Advise on regulatory writing standards, lead writing plans and timelines, and apply AI tools to improve quality and efficiency. Requires strong biostatistics understanding and global regulatory knowledge.

Artificial Intelligence

Today

Imperial College London

Bioinformatics Research Associate

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  • London
  • Hybrid
  • £50,733 – £59,484 pa
  • Mid-level
  • Contract

Lead the harmonisation, integration and analysis of large-scale multi-omics datasets including single-cell transcriptomics, epigenomics and proteomics, building reproducible Nextflow or Snakemake pipelines on HPC or cloud infrastructure. Work with AI and mathematical modelling teams within a multidisciplinary consortium spanning Imperial, UCL and industry partners on an ARIA-funded programme studying innate immune protection against respiratory viral infections.

Nextflow · Snakemake · Unix +3

3 weeks ago

Autolus · 101–500 people · Series C

Associate Director, Apheresis & Infusion Operations

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  • Stevenage
  • Hybrid
  • Director · manages people

Accountable for onboarding and ongoing performance management of apheresis and treatment centres supporting clinical and commercial CAR T-cell therapies across the UK and Rest of World. Serves as the technical operations single point of contact, conducting site assessments, training centre staff, supporting quality systems and deviations, and managing process change rollouts. Involves up to 50% travel and possible management of contract employees.

Electronic Data Management Systems

3 weeks ago

University of Oxford

Postdoctoral Research Assistant in Immunology

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  • Oxford
  • On-site
  • £39,424 – £46,476 pa
  • Mid-level
  • Contract

Carry out research in spatial immunometabolism focused on the germinal centre reaction within the Clarke group at the Kennedy Institute of Rheumatology. The role involves developing new scientific techniques and experimental protocols, testing hypotheses, analysing data, contributing ideas for new projects, and providing guidance to postdocs, technicians and PhD students.

Last month

Pfizer · 10000+ people · Public

Pharmacology Undergraduate

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  • London
  • On-site
  • Entry level
  • Internship

A 12-month industrial placement supporting in vivo pharmacology research within Pfizer's Internal Medicine Innovation Centre. Day-to-day work includes rodent husbandry and welfare, non-surgical procedures under a Home Office licence, ELISAs and in vitro potency assays for biologics, all under an experienced Research Director. Distinct for its strong focus on animal welfare and the 3Rs.

ELISA

Today

Basecamp Research

Senior Research Scientist, AI Safety and Biosecurity

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  • London
  • On-site
  • Senior
  • Permanent

Lead research on the capabilities and risks of biological AI systems, designing evaluations, red-teaming studies and threat models, and developing safeguards across training, model behaviour and access. Work within the frontier model team with access to proprietary genomic data and biological expertise, shaping research priorities and publishing where appropriate.

EDEN · BaseData

Last week

Basecamp Research

Laboratory Technician

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  • London
  • On-site
  • Permanent

Runs a high-throughput sample processing pipeline, performing DNA extraction, normalisation and library preparation on soil, faecal and other environmental samples. Operates automated liquid handling platforms such as Myra9, logs everything in Benchling LIMS, and carries out QC checks while supporting R&D protocol testing in a CL2 lab.

Benchling · Myra9 · Hamilton +2

2 months ago

Wellcome Sanger Institute

cfDNA Postdoctoral Fellow / Senior Postdoctoral Fellow in statistical genomics

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  • Saffron Walden
  • Hybrid
  • £38,570 – £49,893 pa
  • Senior
  • Contract

Develop and apply statistical and deep learning methods to cell-free DNA from pregnant women, calling fetal and maternal genotypes from high-coverage sequence data and building methylation-aware biomarkers for pregnancy complications. Work spans methods development, large cohort application and collaboration with international partners in a statistical genomics group.

Python · R · Unix +6

3 weeks ago
Isomorphic Labs logo

Isomorphic Labs · 201–500 people · Series A

Research Leader (DMPK), Cambridge, MA

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  • Cambridge, United States
  • Hybrid · 3 days in office
  • Lead

Lead DMPK strategy across drug discovery projects, designing screening cascades and mechanistic experiments while integrating DMPK, PD and toxicology data for dose and safety predictions. Work closely with AI/ML platform teams to optimise computational ADME models and author regulatory sections, in a hybrid Cambridge, MA role.

Python · R

2 months ago
Isomorphic Labs logo

Isomorphic Labs · 201–500 people · Series A

Research Leader / Senior Scientist (Computational Drug Design), Cambridge, MA

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  • Cambridge, United States
  • Hybrid · 3 days in office
  • Senior · manages people

Lead computational drug design programs from hit identification through candidate selection, applying AI/ML to cheminformatics workflows and shaping the internal drug design engine. Roles span Program Lead or Computational Chemistry Lead, with some positions managing 2-3 computational chemists in a hybrid Cambridge, MA team.

REINVENT · AlphaFold

2 months ago
Novartis logo

Novartis

Expert Regulatory Writer

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  • London
  • Hybrid
  • £67,900 – £126,100 pa
  • Senior

Lead the authoring of high-complexity regulatory documents and act as Program Writer for complex programmes, overseeing writing strategy, coordination, planning and resourcing. Partner with clinical trial and submission teams, shape data analysis planning, and champion AI tools to improve regulatory writing quality and efficiency.

Artificial Intelligence

Today

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