Biotechnology Jobs

• Waltham, United States
• On-site
• US$284,250 – US$473,750 pa
• Director

Leads clinical development of GU oncology assets, designing and executing Phase 1-3 interventional trials and serving as a core member of the Clinical Matrix Team. Provides real-time medical monitoring, safety review with pharmacovigilance, and authors clinical study reports and regulatory responses. Builds relationships with key external experts and represents the company at advisory boards and medical meetings.

• Stevenage
• On-site
• US$284,250 – US$473,750 pa
• Director

Leads clinical development of GU oncology assets, designing and executing Phase 1-3 interventional trials and serving as a core member of the Clinical Matrix Team. Provides real-time medical monitoring, safety review with pharmacovigilance, and authors clinical study reports and regulatory responses. Builds external expert relationships and represents the company at advisory boards and medical meetings.

• Cambridge, United States
• Hybrid · 3 days in office
• Senior · manages people

Lead computational drug design programs from hit identification through candidate selection, applying AI/ML to cheminformatics workflows and shaping the internal drug design engine. Roles span Program Lead or Computational Chemistry Lead, with some positions managing 2-3 computational chemists in a hybrid Cambridge, MA team.

REINVENT · AlphaFold

• London
• Hybrid · 3 days in office
• Lead · manages people

Lead a team of biologists in the Exploratory Sciences group, owning in vitro pharmacology strategy for novel modalities such as TPD, molecular glues and peptides. Design screening cascades and quantitative assays, manage CRO studies, and champion LLM agentic workflows and in silico hypothesis building alongside ML and engineering colleagues.

SPR · GCI · nanoDSF +5

• Basel, Switzerland
• Hybrid
• Senior
• Permanent

Build physics-grounded machine learning models that combine quantum chemistry with ML to predict small-molecule energetics, conformation, reactivity, binding affinity and free energy. Work in a small-molecule team within AI for Drug Discovery, creating synthetic QM datasets and deployable, scalable pipelines that feed molecular-design tools across Roche, alongside computational and experimental scientists.

PyTorch · JAX · Psi4 +5

• Home Worker
• Remote
• £47,540 – £88,289 pa
• Mid-level

Manages regulatory activities for clinical trial applications across an assigned portfolio, leading high-quality submissions and coordinating responses to Health Authority queries. Works closely with study teams, country leads and cross-functional partners to identify regulatory risks early and secure timely approvals, while contributing to simplification and automation initiatives across Regulatory Affairs.

• Field Force (England / Wales)
• Hybrid
• £32,690 – £60,710 pa

Site-facing role managing Phase I–IV clinical trial sites, acting as the primary contact between the sponsor and sites. Responsibilities include site initiation visits, training, on-site and remote monitoring, risk assessment and mitigation, and closeout activities, working closely with cross-functional teams to ensure data integrity and compliance.

• Leeds
• Hybrid
• Senior
• Permanent

Leads data management activities across early phase trials, including healthy volunteer and patient populations, multi-site studies and reduced timelines. Accountable for all DM deliverables, resource allocation, client relationships and scope changes, while mentoring the internal study team and adopting new DM technologies.

• High Wycombe
• Hybrid
• Mid-level

Independent clinical quality-risk leadership role translating risk signals into proactive mitigation, escalation and inspection readiness across trials and programs. Involves maintaining Clinical Quality Plans, driving risk monitoring reviews, advising on CAPA plans, and leading pre-submission quality portfolio reviews and mock inspections. Combines hands-on risk ownership with cross-functional influence and coaching of team members.

Microsoft Office · Tableau · Spotfire

• Uxbridge
• Hybrid
• Director

Serves as scientific authority for clinical studies across an assigned asset or indication, from protocol development through CSR review and regulatory submission. Leads clinical oversight of study data with Data Management and Programming, may act as Trial Lead on complex global studies, and presents to investigators, KOLs and senior leadership. Also supports process improvement, training and mentoring within the Clinical Capabilities function.