Biotechnology Jobs

• United Kingdom
• Remote
• Director · manages people

Senior physician role providing metabolic therapeutic and drug-development expertise to a clinical research organisation, supporting major proposals and bid defences, client peer-to-peer engagement, and protocol design. Also trains and mentors internal clinical teams, authors regulatory documents, and liaises with investigators and KOLs. Requires an MD with metabolic subspecialty certification and fluency in English and Mandarin, with travel to China.

• United Kingdom
• Remote
• Director · manages people

Senior physician role leading medical science and strategy for oncology across a clinical research business, shaping RFP responses, bid defences and protocol design while engaging client medical leadership. Also provides therapeutic training, mentoring and regulatory document input, working in a matrixed global team with international travel.

• Oxford
• On-site
• Mid-level
• Permanent

Designs and runs quantitative genetics experiments to assess polygenic traits in field environments, managing multi-location field sites and identifying germplasm for trait variation analysis. Works within the Photosynthesis and Yield programme, taking a plants-down approach to build discovery pipelines from natural variation and evolutionary signals, with scope to contribute to publications, IP and commercial translation.

• Oxford
• Hybrid · 4 days in office
• Permanent

Hands-on mechatronics role spanning mechanical design, electrical integration, software and control, turning scientific requirements and prototypes into reliable laboratory machines. Works with automation scientists and specialist engineers across requirements, build, commissioning and operational use, applying iterative hardware development and systems engineering to productionise prototypes with safety and configuration controls.

• Sheffield
• £39,560 – £48,337 pa
• Entry level
• Contract

Lead the design, assembly and clinical validation of a novel dialyser prototype within the Thermofluids Group, testing with blood-mimicking fluids and human blood to assess cleaning efficiency, clotting risk and biocompatibility. Work alongside two other Research Associates covering numerical simulation and experimental fluid dynamics, in collaboration with the Medical School and Sheffield Teaching Hospitals.

• Exeter
• Entry level
• Contract

A cross-institutional PhD studentship analysing whole genome sequencing data from millions of individuals across UK Biobank, All of Us and Our Future Health to identify rare causal variants for musculoskeletal disorders, then functionally validating them in human cell and tissue models using CRISPR-Cas9, transcriptomics and cellular phenotyping. Split between computational genomics at Exeter and laboratory work at Oxford, it develops a dual skill set in statistical genetics and experimental validation.

UK Biobank · All of Us · Our Future Health +4

• Cambridge, United States
• Hybrid · 3 days in office
• Senior · manages people

Designs and implements translational strategies for small molecule oncology and immunology programs, from early discovery through candidate selection and clinical phase. Oversees CRO activities, PK/PD and safety assessments, and biomarker strategies, bridging computational predictions with laboratory validation. Some roles include managing 2-3 in vivo pharmacologists.

Machine Learning · AlphaFold

• London
• On-site
• £47,500 pa
• Entry level
• Contract

Investigates how protein machines remodel microtubules using cryo-electron microscopy, protein reconstitution and fluorescence microscopy. As an early member of a new lab, you will shape the research programme, establish experimental approaches and develop scientific independence while working closely with the group leader.

Cryo-EM

• Liverpool
• On-site
• Permanent

Perform routine, non-routine and stability testing on finished pharmaceutical products at a client site, using HPLC, Dissolution, Karl Fischer and UV techniques. The role also covers technology transfers, analytical validation, GMP data review and OOS investigations, working within a managed services team embedded at the client's facility.

HPLC · Dissolution · Karl Fischer +4

• London
• £47,500 pa
• Entry level
• Contract

Lead a computational project studying how driver mutation clones interact with their microenvironment in chronic liver disease and liver cancer. Develop graph neural networks, transformers and generative AI methods on large-scale spatial genomics, single-cell and imaging data, embedded across the Crick and Wellcome Sanger Institute with joint supervision.

PyTorch · JAX · NumPy +2

• Norwich
• On-site
• £21,805 pa
• Entry level
• Contract

Investigates the repeated evolution of mimicry in Neotropical Corydoradinae catfishes using comparative and population genomics. The project analyses chromosome-level genomes, RNA-seq and whole-genome resequencing data to find signatures of divergent selection, selective sweeps and rapid pigmentation gene evolution, with training in bioinformatics, UNIX/Linux, HPC and R/Python.

RNA-seq · Whole-Genome Resequencing

• Addlestone
• On-site
• £47,557 – £52,010 pa
• Senior · manages people
• Permanent

Lead a UKRI-funded Next Generation Veterinary Vaccines programme, investigating influenza, coronaviruses and zoonotic Disease X threats. Work across multidisciplinary teams using in vitro and in vivo approaches to design and optimise plug-and-play vaccine platforms, assessing immunogenicity, efficacy and antigenic variation. Includes line management, project coordination and work in SAPO4/ACDP3 containment facilities.

SAPO4 · ACDP3

• Liverpool
• On-site
• Permanent

Perform method development and proof-of-concept validation on pharmaceutical raw materials, intermediates and drug substances, mainly APIs, using HPLC, GC and MS. Support technology transfers for novel substances, review data for compliance, investigate OOS/OOE results and document work to client procedures. Based on-site at a client facility as a managed PSS scientist, liaising with client representatives and supporting audits and continuous improvement.

HPLC · GC · MS +7

• Oxford
• Hybrid
• Senior

Perform bioanalytical assays using molecular and cellular techniques such as ddPCR, qPCR, RT-qPCR and gel electrophoresis to quantify RNA in biological matrices. Support phase-appropriate assay development, qualification and validation within a GCLP-compliant clinical framework, partnering with internal and external labs and cross-functional teams. The role blends basic science research, bioanalysis and clinical development, with exposure to digital and automation tools.

Droplet Digital PCR · qPCR · RT-qPCR +2

• Leeds
• Hybrid
• Senior
• Permanent

Leads data management activities across early phase trials, including healthy volunteer and patient populations, multi-site studies and reduced timelines. Accountable for all DM deliverables, resource allocation, client relationships and scope changes, while mentoring the internal study team and adopting new DM technologies.