Biotechnology Jobs

• Oxford
• On-site
• Permanent

Develop and apply computational methods to analyse complex plant genomes, building pipelines for genome assembly, annotation and variant analysis. Work closely with bioinformatics engineers and research scientists to translate biological questions into reproducible workflows and prioritise targets for crop engineering.

• Oxford
• On-site
• Senior
• Permanent

Designs and engineers plant specialised metabolism in cell cultures to produce high-value natural products for health and medicine, applying synthetic biology to optimise biosynthetic pathway flux and product tolerance. Works with AI and robotics teams on model-driven engineering and stage-gated milestones, with a focus on IP generation and translating research into commercial solutions.

• United Kingdom
• Remote
• Senior

Clinical Research Associate role within PPD's Functional Service Provider division, dedicated to a client and embedded in multi-national project teams. You perform and coordinate all aspects of clinical monitoring, conducting monitoring activities independently across challenging projects. Requires ICH-GCP, EU and FDA knowledge, with award-winning training provided.

• United Kingdom
• Remote
• Director · manages people

Senior physician role providing metabolic therapeutic and drug-development expertise to a clinical research organisation, supporting major proposals and bid defences, client peer-to-peer engagement, and protocol design. Also trains and mentors internal clinical teams, authors regulatory documents, and liaises with investigators and KOLs. Requires an MD with metabolic subspecialty certification and fluency in English and Mandarin, with travel to China.

• Sheffield
• £39,560 – £48,337 pa
• Entry level
• Contract

Lead the design, assembly and clinical validation of a novel dialyser prototype within the Thermofluids Group, testing with blood-mimicking fluids and human blood to assess cleaning efficiency, clotting risk and biocompatibility. Work alongside two other Research Associates covering numerical simulation and experimental fluid dynamics, in collaboration with the Medical School and Sheffield Teaching Hospitals.

• Leeds
• On-site
• Senior

Lead early-phase clinical trials as Principal Investigator or Project Physician, taking studies from start-up through closeout and the Clinical Study Report. Work across first-in-human studies, multiple therapeutic areas and an NHS Trust collaboration, with on-call cover and mentoring of less experienced physicians.

MHRA · cGMP · NHS Trust

• Cambridge
• On-site
• Entry level
• Contract

Hands-on laboratory role supporting a state-of-the-art multiomics facility, running Illumina and Nanopore sequencing, bulk RNA/DNA library prep and single-cell workflows such as 10x Genomics and Parse Bio. The post also covers lab automation, instrument maintenance, SOPs, purchasing and advising researchers on experimental design within a collaborative core-facility team.

Illumina · Nanopore · 10x Genomics +3

• Cambridge, United States
• Hybrid · 3 days in office
• Senior · manages people

Lead in vitro and cellular pharmacology strategy for small-molecule drug design programs, defining screening cascades and guiding biophysical, biochemical and cell-based assays from hit identification to candidate selection. Bridge computational AI/ML predictions with laboratory validation, managing CRO partnerships and collaborating with chemistry, structural biology and translational teams.

SPR · ITC · CRO

• Cambridge, United States
• Hybrid · 3 days in office
• Senior · manages people

Designs and implements translational strategies for small molecule oncology and immunology programs, from early discovery through candidate selection and clinical phase. Oversees CRO activities, PK/PD and safety assessments, and biomarker strategies, bridging computational predictions with laboratory validation. Some roles include managing 2-3 in vivo pharmacologists.

Machine Learning · AlphaFold

• Mitcham
• £40,000 – £45,000 pa
• Mid-level
• Permanent

Servicing a wide range of biomedical devices, including high-complexity medical lasers, across a London patch with occasional UK travel and 2-3 overnight stays per month. The role offers manufacturer-funded certification, a progression plan toward senior positions, and time off in lieu for excess hours, with limited overtime supporting work-life balance.

Medical Lasers · Biomedical Devices

• London
• On-site
• Senior
• Permanent

Owns R&D extraction workflow development, adapting and optimising metagenomic DNA/RNA extraction methods across diverse, low-biomass and inhibitor-rich sample types, including HMW extractions for long-read sequencing. Designs controlled experiments, transfers validated methods to production and a global partner network, and works in a data-first lab environment feeding a large gene atlas.

DoE

• Norwich
• On-site
• £21,805 pa
• Entry level
• Contract

Investigates the repeated evolution of mimicry in Neotropical Corydoradinae catfishes using comparative and population genomics. The project analyses chromosome-level genomes, RNA-seq and whole-genome resequencing data to find signatures of divergent selection, selective sweeps and rapid pigmentation gene evolution, with training in bioinformatics, UNIX/Linux, HPC and R/Python.

RNA-seq · Whole-Genome Resequencing

• Oxford
• Hybrid
• Entry level
• Internship

Embedded within multidisciplinary research teams at a fast-paced Oxfordshire site, contributing to drug discovery from target validation through small molecule discovery and optimisation. The placement offers hands-on laboratory work, disease biology exposure and development of practical scientific skills alongside other students.

• Cambridge
• Senior

Acts as subject matter expert for stem cell culture technologies, leading development, optimisation and delivery of cellular systems for drug discovery. Manages multiple cell culture programmes, supplies high-quality cell batches for high-throughput screening, and troubleshoots assays while ensuring biological safety compliance. Collaborates with multidisciplinary teams and external partners across global sites.

Automated Liquid Handling Platforms · High-Throughput Screening

• Leeds
• Hybrid
• Senior
• Permanent

Leads data management activities across early phase trials, including healthy volunteer and patient populations, multi-site studies and reduced timelines. Accountable for all DM deliverables, resource allocation, client relationships and scope changes, while mentoring the internal study team and adopting new DM technologies.