Latest Genetic Engineering Jobs

Director, AI/ML MIDD Oncology Clinical Pharmacology, Modeling and Simulation

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late pre-candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work across small molecules, biologics and antibody drug conjugates, applying AI/ML and quantitative systems pharmacology methods. Presents and defends modelling outcomes to governance boards and regulators, and contributes to protocols, analysis plans and submissions.

GSK Stevenage £119,250 – £198,750 pa

Hybrid

Director, Real World Data Platform and Portfolio Lead

Accountable for the strategic execution and coordination of internal and external real-world data platform partnerships, ensuring RWD delivers insights, models and evidence into R&D and portfolio decisions. Leads above-therapy-area data partnerships across regions, informs data linkage, governance and AI readiness, and works with engineering, DevOps and translational teams on data product roadmaps and trusted research environments.

GSK Stevenage

Associate Director, CMC Regulatory Science - UK

Lead CMC regulatory strategy for UK-manufactured and UK-licensed mRNA products across development, registration and post-approval lifecycle. Act as primary point of contact with the MHRA, oversee submissions and manufacturing change assessments, and shape global regulatory approaches across cross-functional matrix teams.

Moderna London

Hybrid Clearance Required

Associate Director, CMC Regulatory Science - UK

Lead CMC regulatory strategy for UK-manufactured and UK-licensed mRNA products across development, registration and post-approval lifecycle. Act as primary point of contact with the MHRA, oversee CMC submissions and manufacturing change assessments, and shape global regulatory approaches. Based in London or Harwell with regular travel, working in a 70/30 in-office model.

Moderna Clinical Development

Hybrid Clearance Required

Vertex Summer Intern, International Supply Chain (10 weeks)

Internship within the International Supply Chain team, supporting Commercial Supply Operations to ensure medicines reach patients globally. The role offers hands-on exposure to pharmaceutical supply chain operations, with mentorship, networking and career development. Requires full-time availability for 40 hours per week from 24th May to 30th July 2027.

Vertex Pharmaceuticals London

Hybrid Internship

Real World Principal Biostatistician

Leads statistical work for post-marketing clinical trials, observational studies and real world data investigations, serving as Statistics lead on assigned projects. Develops protocols, analysis plans and TFL specifications, collaborating with clinical development, medical affairs, health economics and real world evidence teams. Requires strong SAS and R skills with a drug developer mindset.

Vertex Pharmaceuticals London

Hybrid

Director, Global Real-World Evidence & Health Outcomes Scientist, Oncology

Leads the design and execution of real-world evidence and health outcomes studies for oncology assets, managing timelines, budgets and quality of protocols, analyses and publications. Advises internal medical, market access and commercial teams and external experts on evidence strategy for HTA submissions, reimbursement and value-based pricing. Requires deep knowledge of RWD sources and payer evidence needs.

GSK Baar Onyx US$204,000 – US$340,000 pa

Hybrid

Senior Medical Director, Oncology Clinical Development - Lung

Senior physician leader providing medical oversight, safety monitoring and clinical insight across lung cancer studies, from protocol design through data interpretation. Serves on the Clinical Matrix Team, contributes to regulatory interactions and external scientific engagement, and mentors Medical Directors within the programme. Requires deep lung cancer drug development expertise, including early phase trials.

GSK USA - Pennsylvania - Upper Providence US$242,550 – US$404,250 pa

On-site

Medical Director, Oncology Clinical Development - Lung & Head/Neck Cancers

Serves as the physician within oncology clinical programme teams for lung and head/neck cancers, leading medical monitoring, safety oversight and clinical data interpretation across Phase I–III studies. Partners with a Senior Scientist and cross-functional matrix teams on protocol development, regulatory interactions and investigator engagement, with on-site presence 2–3 days per week.

GSK USA - Pennsylvania - Upper Providence US$222,750 – US$371,250 pa

On-site

Senior Medical Director, Oncology Clinical Development - GU

Leads clinical development of GU oncology assets, designing and executing Phase 1-3 interventional trials and serving as a core member of the Clinical Matrix Team. Provides real-time medical monitoring, safety data review with pharmacovigilance, and authors clinical study reports and regulatory responses. Builds key external expert relationships and contributes to business development diligence.

GSK USA - Pennsylvania - Upper Providence US$284,250 – US$473,750 pa

On-site

Executive Medical Director, Clinical Development Lead - Oncology GU

Owns the clinical strategy, scientific narrative and benefit-risk framework for a genitourinary oncology asset, acting as the senior clinical authority on the Medicine Development Team core quad. Sets asset-level evidence-generation and governance strategy while study-level delivery is led by Senior Scientists, and represents Clinical Development in health authority interactions, advisory boards and alliance partnerships. Also mentors clinical development talent and applies AI-enabled analytics to sharpen development decisions.

GSK USA - Pennsylvania - Upper Providence US$284,250 – US$473,750 pa

Hybrid

Clinical Development Medical Director- Hepatology

Leads clinical development strategy for hepatology assets within the Respiratory, Immunology & Inflammation Research Unit, from target identification through proof-of-concept studies. Accountable for clinical matrix team leadership, protocol design, medical monitoring and safety governance, and regulatory interactions across all development phases.

GSK Upper Providence US$202,500 – US$371,250 pa

Hybrid

Medical Director, Oncology Clinical Development - GU

Serves as the physician within a clinical program team, leading medical monitoring and safety oversight for genitourinary oncology studies. Interprets clinical and safety data, contributes to protocol development and regulatory interactions, and acts as a core member of the Clinical Matrix Team. May guide other physicians on complex multi-study programs.

GSK USA - Pennsylvania - Upper Providence US$189,750 – US$316,250 pa

Hybrid

Medical Director Clinical Development- Aging

Provides clinical and scientific leadership across translational and clinical studies within GSK's Respiratory, Immunology & Inflammation Research Unit, focusing on aging. Leads the Clinical Matrix Team, designs clinical development plans and protocols, oversees medical monitoring and safety, and drives regulatory interactions. Works cross-functionally with biology, regulatory, commercial and statistics to advance assets from early development.

GSK USA - Pennsylvania - Upper Providence US$189,750 – US$316,250 pa

Hybrid

Medical Director-Oncology Clinical Development - GI

Serves as the physician within an oncology clinical programme team, leading medical monitoring and safety oversight for GI cancer studies. Interprets clinical and safety data, contributes to protocol development, and engages investigators, KEEs and health authorities. A core member of the Clinical Matrix Team, providing medical guidance within a matrixed pharma R&D environment.

GSK USA - Pennsylvania - Upper Providence US$222,750 – US$371,250 pa

On-site