Latest Drug Discovery Jobs

Computational Drug Designer, London

As a Computational Drug Designer, you will work on cutting-edge drug discovery projects, applying AI and computational chemistry to design novel molecules. You will collaborate with interdisciplinary teams, contribute to scientific proposals, and mentor junior colleagues in a fast-paced, innovative environment.

Isomorphic Labs United Kingdom

Hybrid Permanent

Senior Computational Biologist – Early Discovery Immunology

A Senior Computational Biologist will lead target discovery and validation in immunology and inflammatory diseases by integrating multimodal biological data from Recursion’s platform. The role involves developing computational methods, collaborating across disciplines, and driving data-informed decisions to advance drug programs. The scientist will work closely with biologists, chemists, and engineers in a fast-paced, AI-driven environment focused on accelerating therapeutic development.

Recursion United Kingdom £151,800 – £220,660 pa

Hybrid Permanent

Senior Computational Biologist - Early Discovery Oncology

This role involves driving target discovery in precision oncology by integrating large-scale biological datasets such as phenomics, transcriptomics, and genomics to identify and validate novel therapeutic targets. The computational biologist will develop and scale innovative analysis methods, collaborate across multidisciplinary teams, and translate findings into actionable drug discovery programs. Emphasis is placed on using advanced computational techniques to support early translational strategies and accelerate the nomination of precision oncology therapies.

Recursion United Kingdom £151,800 – £220,660 pa

Hybrid Permanent

Medicinal Drug Design Lead, London

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.The future is coming. A future enabled and enriched by the incredible power of machine learning. A...

Isomorphic Labs London, United Kingdom

Machine Learning Scientist - Small Molecule Drug Design

Develop and apply machine learning models to accelerate small-molecule drug discovery with a focus on protein–ligand interactions, binding affinity, and molecular properties. Collaborate closely with computational chemists, structural biologists, and experimental researchers to validate and refine ML-generated hypotheses. Contribute to scientific impact through publications, open-source contributions, and conference engagement.

Roche Welwyn Hatfield, United Kingdom

Hybrid Permanent

Machine Learning Scientist - Small Molecule Drug Design

Develop and apply machine learning models for small-molecule drug design with a focus on protein–ligand interactions, binding affinity, and molecular properties. Collaborate with computational chemists, structural biologists, and medicinal chemists to validate and refine ML-generated hypotheses. Work within a multidisciplinary team to drive innovation in drug discovery using structure-driven approaches and foundation models.

Roche Switzerland

Hybrid Permanent

VP & Global Head, Discovery Chemistry and DMPK, Oncology Targeted Delivery

This role involves leading the global Discovery Chemistry and DMPK function within AstraZeneca's Oncology Targeted Delivery (OTD) organization. Responsibilities include setting strategic direction, driving innovation in small molecules, ADCs, and RCs, and fostering a high-performing, collaborative culture across R&D sites in Cambridge (UK), Cambridge (MA), and Gaithersburg (US).

AstraZeneca Cambridge, United Kingdom

On-site Permanent

VP & Global Head, Discovery Chemistry and DMPK, Oncology Targeted Delivery

This role involves leading the global Discovery Chemistry and DMPK function within AstraZeneca's Oncology Targeted Delivery (OTD) organization. Responsibilities include setting strategic direction, driving innovation in small molecules, ADCs, and RCs, and fostering a high-performing, collaborative culture across R&D sites.

AstraZeneca United States

On-site Permanent

Medical Director, Gastroenterology, Early Clinical Development

This role involves leading global clinical trial teams through phase 1 and 2 development, drafting early clinical development plans, and serving as a medical lead for early clinical studies. The Medical Director will collaborate with biomarker experts, research scientists, and key opinion leaders to identify and implement strategies for preclinical and clinical support of gastroenterology programs.

Novartis London, United Kingdom

Hybrid Permanent

Product Manager - Antibody Applications

Nuclera is a venture-backed biotech company headquartered in Cambridge, UK with significant operations in Boston, USA. Nuclera’s mission is to accelerate discovery by enabling rapid, easy access to functional proteins essential for drug discovery research. Our eProtein Discovery™ benchtop system...

Nuclera Cambridge, United Kingdom

Hybrid Permanent

Field Service Engineer

This role involves installing, commissioning, and maintaining electromechanical laboratory instrumentation at customer sites across the UK. The engineer provides technical support, performs preventative maintenance and calibration, and trains end-users in system setup and optimisation. The position requires strong troubleshooting skills, customer-facing abilities, and occasional travel with overnight stays.

Taylorollinson East Midlands, United Kingdom £35,000 – £40,000 pa

Hybrid Permanent

Metabolite Identification Specialist

This role involves leading metabolite identification and biotransformation studies to determine the metabolic fate of drug candidates. The specialist will design and interpret advanced analytical data using techniques like high-resolution mass spectrometry, support drug discovery and development programmes, and provide scientific guidance to project teams and junior scientists. The position emphasizes technical leadership, problem-solving in complex metabolic pathways, and direct contribution to the progression of pharmaceutical candidates.

SRG Sandwich, United Kingdom

On-site Permanent

Senior Director Translational Data Sciences

This role involves developing and executing a translational data strategy that bridges the gap between disease biology and clinical outcomes. The Senior Director will lead a team in integrating multi-omics data with AI-driven analytics, forming strategic partnerships, and ensuring clinical relevance in all analytical platforms.

GSK Stevenage, United Kingdom

On-site Permanent

Senior Director Translational Data Sciences

This role involves developing and executing a translational data strategy that bridges the gap between disease biology and clinical outcomes. The Senior Director will lead a team in integrating multi-omics data with AI-driven analytics, forming strategic partnerships, and ensuring clinical relevance in all analytical platforms.

GSK

On-site Permanent

Forward Deployed AI Engineer

This role involves working directly with end clients to deploy an AI platform from trial to production, leading technical delivery, designing AI-driven workflows, and integrating knowledge graph data. The position requires a strong engineering background, experience with LLMs, and the ability to communicate with both technical and non-technical stakeholders.

Harnham - Data & Analytics Recruitment London, United Kingdom £80,000 – £130,000 pa

Hybrid Permanent Flexible