Biotechnology Jobs

Senior Clinical Trial Manager, Cambridge, MA

The role involves end-to-end management of clinical trials within a fast-paced, AI-driven drug discovery environment. The Senior Clinical Trial Manager will lead cross-functional teams, oversee trial start-up through close-out, ensure compliance with ICH/GCP standards, and integrate AI innovations into clinical operations. Key responsibilities include vendor and budget management, clinical documentation, data oversight, and supporting regulatory readiness and audits.

Isomorphic Labs Cambridge, United Kingdom

Hybrid Permanent

Senior Medical Director Early Clinical Respiratory

This role involves leading early-phase clinical development in respiratory therapeutics, designing and overseeing Phase 1 and 2a trials, and translating scientific innovation into clinical proof-of-concept. The individual will act as a medical expert, shaping clinical strategies, guiding regulatory interactions, and mentoring teams within a global, collaborative environment. Emphasis is placed on biomarker use, translational research, and engagement with external scientific leaders.

AstraZeneca Cambridge, United Kingdom

Pathology Director

Leads medical and technical oversight of an accredited diagnostic laboratory supporting clinical trials and biomarker development. Provides expert interpretation of pathology and biomarker data, ensures regulatory compliance, and drives innovation in digital pathology and companion diagnostics. Works cross-functionally to integrate advanced diagnostic methods into drug development programs.

AstraZeneca Cambridge, United Kingdom

Director of Clinical Pharmacology, Cambridge, MA

Lead clinical pharmacology strategy for small molecule programs in oncology and non-oncology areas, designing and executing studies from Phase 1 through late development. Utilize AI-driven models for PK/PD prediction, dose optimization, and regulatory submissions, while managing CROs and translating preclinical data into human dosing strategies.

Isomorphic Labs Cambridge, United Kingdom

12 Month University Industrial Placement Student: Biologics Engineering

This 12-month industrial placement offers hands-on laboratory experience in biologics engineering, focusing on protein engineering, molecular biology, and cell-based technologies to advance therapies like monoclonal and bispecific antibodies. You'll contribute to drug discovery projects in respiratory, oncology, and immunology, gaining real-world research experience within a supportive, international R&D team.

AstraZeneca Cambridge, United Kingdom £28,000 pa

Senior Scientist - Cell Therapy Safety

The role involves developing and validating in vitro models to assess the pre-clinical safety of cellular therapeutics, including autologous, allogeneic, and in vivo CAR-T. The scientist will apply molecular biology and immunology techniques to evaluate toxicity, immunogenicity, and tumorigenicity, while collaborating across disciplines to inform safety strategies. The position emphasizes innovation, external scientific engagement, and contributing to non-clinical toxicology packages for novel cell therapies.

AstraZeneca Cambridge, United Kingdom

On-site Permanent

12 Month University Industrial Placement Student: Computational Chemistry

This 12-month industrial placement offers hands-on experience in computational chemistry within AstraZeneca’s Oncology Medicinal Chemistry Department in Cambridge. The role involves applying machine learning, generative AI, and physics-based modelling to support drug discovery, including structure- and ligand-based design, cheminformatics workflows, and molecular dynamics simulations. The student will work alongside experienced scientists in a collaborative, innovation-driven environment at one of the world’s leading biopharma R&D centres.

AstraZeneca Cambridge, United Kingdom £28,000 pa

12 Month University Industrial Placement Student: Oncology DMPK

This 12-month industrial placement involves conducting DMPK bioanalysis and in vitro ADME studies to evaluate drug candidates in oncology. The role includes training in mass spectrometry, supporting pharmacokinetic research, and working within a cross-disciplinary matrix team across the UK and US. It offers hands-on experience in drug discovery within a leading biopharmaceutical R&D environment.

AstraZeneca Cambridge, United Kingdom £28,000 pa

Senior Scientist, Research Informatics & Data Science

This role involves developing data, software, and automation solutions to transform biologics engineering workflows. The scientist will integrate laboratory systems, build FAIR data foundations in Snowflake, and apply AI to enhance drug discovery. Collaboration with scientists, engineers, and IT teams is central to delivering scalable, user-centric digital products that improve data quality and research efficiency.

AstraZeneca Cambridge, United Kingdom

Research Scientist – In vitro display, Biologics discovery

This role involves the discovery and optimisation of peptides and biologics using in vitro display platforms such as phage, yeast, mRNA, and ribosome display. The scientist will design and execute experiments, analyse data, and collaborate with multidisciplinary teams to advance therapeutic programmes. The position emphasizes hands-on molecular biology, library generation, and selection techniques within a cutting-edge, AI-informed drug discovery environment.

AstraZeneca Cambridge, United Kingdom

Hybrid Permanent

Executive Director, Strategy, Oncology R&D

This role involves leading the global Oncology R&D strategy at AstraZeneca, shaping high-impact therapeutic area strategies by integrating clinical, scientific, and commercial insights. The individual will advise senior leadership, drive portfolio optimization, and influence strategic investment decisions with a focus on patient outcomes and innovation. It requires deep scientific and strategic expertise, strong analytical rigor, and the ability to lead cross-functionally in a complex, matrixed environment.

AstraZeneca Cambridge, United Kingdom

On-site Permanent

Director, Translational Data Enablement

Leads the transformation of translational and biomarker data into standardized, AI-ready data products to accelerate drug discovery. Manages a distributed team of data professionals and drives cross-functional alignment on data standards, FAIR principles, and automation. Focuses on scalable data product delivery, semantic integration, and emerging technologies like agentic AI to enable precision medicine and biomarker research across therapeutic areas.

AstraZeneca Cambridge, United Kingdom

Hybrid Permanent

Senior Director Project Toxicologist

This role involves leading regulatory toxicology strategies for late-stage clinical and marketed products across multiple therapy areas, with a focus on safety risk assessment and global marketing applications. The Senior Project Toxicologist provides non-clinical safety expertise, supports regulatory submissions, and mentors teams through the drug development lifecycle. Based in Cambridge, the position operates within a collaborative R&D environment, requiring deep scientific and regulatory knowledge in toxicology.

AstraZeneca Cambridge, United Kingdom

Senior Research Scientist - Omics, Bioscience, Oncology Targeted Delivery

This role involves hands-on laboratory work and data analysis in genomics, transcriptomics, and single-cell sequencing to support oncology drug discovery. The scientist will develop and optimise NGS workflows, process and interpret complex omics datasets, and collaborate across disciplines to translate findings into scientific insights. Emphasis is placed on integrating experimental and computational approaches, with opportunities to apply AI-enabled tools for enhanced data interpretation and workflow efficiency.

AstraZeneca Cambridge, United Kingdom

12 Month University Industrial Placement Student (UIPS): Discovery Sciences

This 12-month industrial placement offers hands-on experience in drug discovery within AstraZeneca’s Discovery Sciences team in Cambridge. You’ll work on laboratory-based projects involving assay development, automation, advanced cell models, and data analysis using tools like GraphPad Prism and AI-enabled platforms. The role emphasizes collaboration, scientific communication, and contributing to innovative research in a global, inclusive environment.

AstraZeneca Cambridge, United Kingdom £28,000 pa