39 jobs for “Protein Engineer”
Isomorphic Labs London
Lead pharmacology and translational biology strategy for large molecule therapeutics, designing in vivo efficacy and complex in vitro functional assays. Act as Biology Lead on projects, coordinating internal workflows and external CROs, and collaborate with ML and computational biology teams to feed data into generative AI design loops.
Evotec Abingdon
Leads Evotec's consolidated AI Accelerator, owning machine learning, generative and agentic AI, and therapeutic hypothesis groups. Sets the AI vision and roadmap, makes build/buy/partner decisions for the AI stack, and turns proprietary multi-omics and experimental data into predictive models and reusable IP. Acts as the senior external technical voice for AI in drug discovery.
Basecamp Research London
Owns R&D extraction workflow development, adapting and optimising metagenomic DNA/RNA extraction methods across diverse, low-biomass and inhibitor-rich sample types, including HMW extractions for long-read sequencing. Designs controlled experiments, transfers validated methods to production and a global partner network, and works in a data-first lab environment feeding a large gene atlas.
Evotec Macclesfield
Designs and executes work plans for early drug discovery projects within a Protein Sciences team, supporting multiple projects and presenting results to clients. Hands-on role focused on recombinant protein expression using insect cell systems such as BEVS, S2 and Sf9, including construct design, baculovirus generation and troubleshooting difficult targets like membrane proteins.
Nuclera Cambridge
Formulate, dispense and quality-control reagents for a protein discovery platform, operating lab equipment such as pipettes, centrifuges and UPLC systems. The role covers batch documentation, inventory management via ERP and troubleshooting production deviations, working closely with R&D, QA and Supply Chain in a fast-paced lab environment.
Nexus Life Sciences Belfast £50,000 – £60,000 pa
Leads a Clinical Method Development and Validation team, overseeing bioanalytical method delivery for a New Product Development programme. Provides technical leadership in a GLP-compliant lab, acting as expert in extraction techniques and optimising HPLC, UPLC and LCMSMS systems while mentoring the team.
CSL Maidenhead US$212,000 – US$251,000 pa
Leads the full statistical contribution to a clinical development programme, defining statistical strategy for trial design, analysis and regulatory submissions, and representing Biostatistics in interactions with the FDA, EMA and PMDA. Also manages outsourcing to CROs/FSPs and contributes to governance and development-plan decisions across therapeutic areas.
CSL Breda, Netherlands US$212,000 – US$251,000 pa
Leads the full scope of statistical contribution to a clinical development programme, defining statistical strategy and methodologies for trial design, analysis and regulatory submissions. Represents Biostatistics in interactions with authorities such as FDA, EMA and PMDA, and manages outsourcing or internal statistical programmers. Two positions support multiple therapeutic areas.
Isomorphic Labs London
Contribute to the design of novel large-molecule therapeutics by applying computational and machine learning methods to predict biologics properties such as affinity, developability and immunogenicity from sequence. Work within an interdisciplinary computational sciences team alongside ML and biologics discovery experts, benchmarking models, analysing lab data and shaping data-generation strategies for active learning.
Vertex Pharmaceuticals Oxford
Lead the DMPK team at Vertex's Oxford site, shaping strategy and operations while sitting on both the Global DMPK and Oxford Site leadership teams. The role directs ADME science across discovery and development programmes, partners with Medicinal Chemistry, Biology, Preclinical Safety and Clinical Pharmacology, and oversees regulatory documentation such as INDs and marketing applications. It combines deep small-molecule DMPK expertise with hiring, mentoring and resource planning.
IQVIA Cambridge
A senior scientific leadership role shaping and delivering a drug discovery strategy, driving adoption of AI-assisted design, predictive modelling, automation and computational science across a diverse portfolio. The post-holder mentors multidisciplinary teams spanning biology, chemistry, protein design, pharmacology and translational sciences, and acts as a scientific ambassador in client engagements, proposals and partnerships.
Moderna Oxford
Develops, validates and runs ligand-binding and cell-based bioanalytical assays generating pharmacodynamic and immunogenicity data for clinical mRNA programmes. Works in a GcLP-regulated lab using Thermo Watson LIMS and electronic notebooks, handling clinical samples, critical reagents, SOPs and validation reports while partnering with Clinical Operations and Sample Management.
