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Senior Clinical Trial Case Manager

Manages clinical trial case management activities, ensuring compliance with international and national regulations including GxP and pharmacovigilance standards. Oversees safety reporting, vendor performance, and case processing for serious adverse events, while acting as a key liaison for inspections and audits. Provides training, supports database enhancements, and ensures accurate coding and consistency in safety data analysis.

CSL

Hybrid Permanent

Senior Scientist (In vitro / Cellular Pharmacology), Cambridge, MA

This role involves designing and executing biological screening cascades to validate computational predictions in drug discovery. The scientist will lead biophysical, biochemical, and cellular assay development, collaborate with CROs, and bridge AI-driven insights with experimental validation across oncology and immunology programs. Close collaboration with medicinal chemistry, structural biology, and machine learning teams ensures data informs rational drug design.

Isomorphic Labs

England

Hybrid Permanent

Principal Scientist Predictive Agentic Target Biology

Lead the development and application of predictive computational models and agentic workflows to evaluate the tractability and safety of biological targets for drug discovery. Integrate multimodal data including genomics, proteomics, and functional screens to inform target prioritisation and mechanism of action. Collaborate with biologists, data scientists, and project teams to translate biological questions into robust, reproducible pipelines that guide go/no-go decisions in early drug development.

GSK

Stevenage, United Kingdom

On-site Contract

(Fixed Term) Scientist, Immunogenicity, Bioanalytical and Molecular Assays

This role involves designing and executing bioanalytical and immunogenicity strategies to support mRNA-based therapeutic development. The scientist will lead assay development for clinical programmes using platforms like ELISA, MSD, and cell-based methods, ensuring regulatory compliance and robust data generation. The position emphasizes collaboration across multidisciplinary teams and integration of digital tools and AI to advance Moderna's pipeline.

Moderna

Oxford, United Kingdom

Pathology Director

Leads medical and technical oversight of an accredited diagnostic laboratory supporting clinical trials and biomarker development. Provides expert interpretation of pathology and biomarker data, ensures regulatory compliance, and drives innovation in digital pathology and companion diagnostics. Works cross-functionally to integrate advanced diagnostic methods into drug development programs.

AstraZeneca

Cambridge, United Kingdom

£297,000 – £356,400 pa

Executive Director, Asset Strategy Leadership

Leads strategic positioning of clinical assets in oncology and immunology, leveraging AI-driven insights from the Recursion OS to inform go/no-go decisions, competitive differentiation, and portfolio prioritization. Works cross-functionally with clinical, platform, and business development teams to align resource allocation and advance transformative medicines. Focuses on integrating mechanistic, biomarker, and market data to build compelling narratives for internal and external stakeholders.

Recursion

North Tyneside, NE29 8EP, United Kingdom