Jobs in Cambridge

Senior Scientist (In vitro / Cellular Pharmacology), Cambridge, MA

This role involves designing and executing biological screening cascades to validate computational predictions in drug discovery. The scientist will lead biophysical, biochemical, and cellular assay development, collaborate with CROs, and bridge AI-driven insights with experimental validation across oncology and immunology programs. Close collaboration with medicinal chemistry, structural biology, and machine learning teams ensures data informs rational drug design.

Isomorphic Labs England

Hybrid Permanent

Senior Scientist (In vivo Pharmacology & Translational Sciences), Cambridge, MA

Lead translational strategies for oncology and immunology programs by designing in vivo pharmacology and PK/PD studies to validate AI-designed drug candidates. Bridge computational predictions with experimental validation through CRO partnerships and biomarker-driven approaches. Drive preclinical data generation to inform clinical trial design and regulatory filings.

Isomorphic Labs England

Hybrid Permanent

Associate Director, Management - Scientific Services

This role involves managing outsourced scientific services across laboratory equipment maintenance, support, and waste services at AstraZeneca’s Cambridge site. The individual will provide strategic contract oversight, ensure supplier compliance with service agreements and regulatory standards (SHE/GxP), and collaborate with procurement and lab leaders. Key responsibilities include performance monitoring, risk management, budget contribution, and resolving operational escalations within the scientific services delivery chain.

AstraZeneca Cambridge, United Kingdom

Contract

Associate Principal Scientist, AI and Computational Tools, Oncology R&D (1-year

This role involves designing and deploying AI-powered tools and computational workflows to accelerate oncology drug discovery, with a focus on immuno-oncology. The scientist will build scalable data infrastructure, develop agentic AI and LLM-integrated solutions, and act as a technical leader across dry-lab and wet-lab teams. The position emphasizes translating complex biological data—such as single-cell and spatial transcriptomics—into reproducible, insight-generating systems while mentoring others in AI adoption and best practices.

AstraZeneca Cambridge, United Kingdom

On-site Contract

Medical Director, Clinical Development, Hepatology

A Medical Director in Clinical Development for Hepatology will lead clinical strategy and execution for liver disease programs, contributing to clinical development plans, study design, and regulatory submissions. This role involves cross-functional collaboration, medical oversight of clinical trials, and integration of scientific and regulatory insights to advance GSK’s pipeline. The position plays a key part in driving transformative medicines from development through to approval, with a focus on scientific rigor and patient impact.

GSK United States

Medical Director, Clinical Development, Hepatology

A Medical Director in Clinical Development for Hepatology will lead clinical strategy and execution for liver disease assets, contributing to clinical development plans, study design, and regulatory submissions. The role involves cross-functional leadership, medical oversight of trials, and integration of scientific and clinical insights to advance drug development. It operates within a hybrid model, requiring on-site presence several days a week.

GSK US$222,750 – US$371,250 pa

Innovation, Data & Analytics Team, Senior Data Scientist (AI Lead)

This role involves leading the analytical methodology and evaluation rigor for AI-based workflows within Pfizer's Innovation, Data & Analytics team. The Senior Data Scientist will direct model selection, cohort/segmentation science, and agent decision logic, working closely with engineering and governance teams. They will also mentor junior colleagues and drive innovation in agentic systems using real-world healthcare data sources such as EHR and claims.

Pfizer US$162,900 – US$271,500 pa

Innovation, Data & Analytics Team, Senior Data Scientist (AI Lead)

Lead the methodological direction of AI-driven workflows, designing model selection frameworks, cohort segmentation, and agent decision logic using real-world healthcare data. Partner with engineering and governance teams to translate analytical rigor into production systems, while mentoring junior scientists and advancing AI innovation across medical and commercial use cases in a regulated pharma environment.

Pfizer US$162,900 – US$271,500 pa

Innovation, Data & Analytics Team, Senior Manager, Data Scientist

A Senior Manager, Data Scientist role within Pfizer's Innovation, Data & Analytics (IDA) Team, focused on designing and applying advanced analytical and AI-driven methods to support data-informed decision-making in Medical Affairs. The role involves leading model development, cohort segmentation, and evaluation frameworks while collaborating with engineering, governance, and business stakeholders. It emphasizes methodological rigor, responsible AI use, and translating complex medical and business questions into scalable analytical solutions.

Pfizer US$124,400 – US$207,400 pa

Innovation, Data & Analytics Team, Senior Manager, Data Scientist

A Senior Manager, Data Scientist role in Pfizer's Innovation, Data & Analytics (IDA) team, focused on designing and applying advanced analytical and AI-driven methods to support Medical Affairs. The role involves leading model development, cohort segmentation, and validation frameworks while collaborating with engineering, governance, and business stakeholders. It emphasizes responsible AI use, real-world healthcare data analysis, and translating complex medical questions into scalable data solutions.

Pfizer £124,400 – £207,400 pa