Jobs in Cambridge

Director of Clinical Pharmacology, Cambridge, MA

Lead clinical pharmacology strategy for small molecule programs in oncology and non-oncology areas, designing and executing studies from Phase 1 through late development. Utilize AI-driven models for PK/PD prediction, dose optimization, and regulatory submissions, while managing CROs and translating preclinical data into human dosing strategies.

Isomorphic Labs Cambridge, United Kingdom

Director of Nonclinical Safety, Cambridge, MA

Lead the development and execution of nonclinical safety strategies for small molecule drug candidates in oncology and non-oncology programs, integrating AI-driven predictive models with traditional toxicology. Build and scale the nonclinical safety function within an AI-first drug discovery environment, ensuring high-quality data feedback to refine computational models. Collaborate across preclinical, clinical, and regulatory teams to advance compounds through IND and NDA/MAA-enabling studies.

Isomorphic Labs Cambridge, United Kingdom

Senior Scientist - Cell Therapy Safety

The role involves developing and validating in vitro models to assess the pre-clinical safety of cellular therapeutics, including autologous, allogeneic, and in vivo CAR-T. The scientist will apply molecular biology and immunology techniques to evaluate toxicity, immunogenicity, and tumorigenicity, while collaborating across disciplines to inform safety strategies. The position emphasizes innovation, external scientific engagement, and contributing to non-clinical toxicology packages for novel cell therapies.

AstraZeneca Cambridge, United Kingdom

On-site Permanent

Senior Director Project Toxicologist

This role involves leading regulatory toxicology strategies for late-stage clinical and marketed products across multiple therapy areas, with a focus on safety risk assessment and global marketing applications. The Senior Project Toxicologist provides non-clinical safety expertise, supports regulatory submissions, and mentors teams through the drug development lifecycle. Based in Cambridge, the position operates within a collaborative R&D environment, requiring deep scientific and regulatory knowledge in toxicology.

AstraZeneca Cambridge, United Kingdom

Medical Director, Clinical Development, Hepatology

Lead clinical development activities for hepatology-focused drug programs, contributing to clinical trial design, regulatory submissions, and cross-functional strategy. Provide medical oversight and scientific leadership within project teams, ensuring patient safety and regulatory compliance. Engage with regulators, payors, and external experts to advance GSK’s pipeline in liver diseases.

GSK London, United Kingdom

Director, AI/ML MIDD Oncology Clinical Pharmacology, Modeling and Simulation

Lead and execute model-informed drug development strategies in oncology, applying advanced pharmacometric and AI/ML techniques to optimize clinical trial design, dose selection, and regulatory submissions. Drive innovation in exposure-response analysis, population PK/PD, and quantitative systems pharmacology within a cross-functional R&D environment.

GSK Stevenage, United Kingdom £119,250 – £198,750 pa

Innovation, Data & Analytics Team, Senior Data Scientist (AI Lead)

This role involves leading the analytical methodology and evaluation rigor for AI-based workflows within Pfizer's Innovation, Data & Analytics team. The Senior Data Scientist (AI Lead) will design model selection frameworks, define cohort and segmentation strategies using real-world healthcare data, and direct the logic behind agentic decision systems. Collaboration with engineering, governance, and data architecture teams is central, along with mentoring junior scientists and driving innovation in AI/ML applications across the pharmaceutical lifecycle.

Pfizer

Hybrid Permanent

Innovation, Data & Analytics Team, Senior Data Scientist (AI Lead)

Lead the design and evaluation of AI-driven workflows, focusing on model selection, cohort segmentation, and agent decision logic using real-world healthcare data. Collaborate with engineering and governance teams to translate advanced methodologies into production systems while mentoring junior scientists. Focus on rigorous, defensible analytics within the pharmaceutical domain, leveraging LLMs and agentic systems in a regulated environment.

Pfizer US$162,900 – US$271,500 pa

Head of Computer-Aided Drug Discovery (CADD)

Lead a computational drug discovery team focused on structure- and fragment-based design, integrating AI/ML, cheminformatics, and advanced simulation methods into multidisciplinary drug discovery programmes. Drive computational strategy while maintaining hands-on involvement in projects from hit identification through to candidate nomination. Collaborate closely with medicinal chemistry, structural biology, and biophysics teams to deliver innovative therapeutics.

VRS UK Cambridge, Cambridgeshire, United Kingdom

Field Sales Agent

Act as a self-employed field sales agent promoting point-of-care diagnostic solutions to healthcare providers including care homes, pharmacies, and GP practices. Leverage existing relationships to sell diagnostic devices and reagent cartridges, supported by full training and biomedical expertise. Generate income through upfront and recurring commissions from consumable sales.

Sales Agents Plus Birmingham, West Midlands (county), United Kingdom

Senior Scientist, Automated Diagnostic Systems - Pathogen

This role involves developing and optimizing automated workflows for a sample-to-answer diagnostic platform using whole genome sequencing. The scientist will translate molecular biology processes into integrated fluidic systems, focusing on nucleic acid extraction, library preparation, and assay robustness. Collaboration with engineers and chemists is central to advancing the platform from concept to prototype.

Ellison Institute of Technology Oxford, United Kingdom

On-site Permanent

Director - Immunoassay Development

Lead the development and optimisation of quantitative immunoassays for at-home diagnostic tests, from initial design through validation and commercialisation. This hands-on leadership role involves managing scientific collaborators, ensuring regulatory compliance, and translating lab-based assays into point-of-care formats such as lateral flow and microfluidic cartridges. Work with human biological samples and drive assay performance in sensitivity, precision, and stability.

Talentmark Stevenage, Hertfordshire, United Kingdom £75,000 – £100,000 pa

Fluidic System Engineer - Pathogen

Design and develop microfluidic systems for a point-of-care diagnostic device that enables metagenomic sequencing through a cartridge-based interface. Work closely with cross-functional teams to integrate microfluidics with instrumentation, electronics, and firmware, focusing on robustness, automation compatibility, and real-world performance. Conduct prototyping, testing, and validation using techniques like soft lithography and rapid prototyping to advance decentralized infectious disease diagnostics.

Ellison Institute of Technology Oxford, United Kingdom

On-site